Parvovirus B19 infection in a liver transplant recipient: case report and review in organ transplant recipients.

Abstract:

:We report an adult liver transplant recipient with parvovirus B19 infection, presenting as chronic transfusion-dependent anemia ensuing 1 month post-transplantation. Both serum and bone marrow cells were positive for parvovirus B19 DNA detected by polymerase chain reaction. The bone marrow biopsy revealed erythroid hypoplasia with a selective decrease of nucleated red cell precursors, and giant pronormoblasts with prominent intranuclear inclusions, characteristic of parvovirus B19 infection. Anemia and viremia resolved shortly after administration of immunoglobulin, suggesting a therapeutic role. This case and several similar ones in the literature provide justification for a controlled clinical trial of immunoglobulin for parvovirus-induced anemia in transplant recipients.

journal_name

Clin Transplant

journal_title

Clinical transplantation

authors

Chang FY,Singh N,Gayowski T,Marino IR

subject

Has Abstract

pub_date

1996-06-01 00:00:00

pages

243-7

issue

3

eissn

0902-0063

issn

1399-0012

journal_volume

10

pub_type

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