Impact of the ratio of graft kidney volume to recipient body surface area on graft function after live donor kidney transplantation.

Abstract:

:Functioning nephron mass is a determinant of the graft function of kidney transplant recipients. The graft kidney volume and its weight have been reported to be surrogates of the nephron mass. To investigate the impact of the ratios of the surrogates to recipient body surface area (BSA) and body weight on the graft function within six months post-transplantation, we measured the graft kidney volume, using computed tomography with 3-dimensional reconstruction before transplantation, and measured the graft kidney weight during surgery. Ninety-four cases of live donor kidney transplants were included in this study. The graft kidney volume/recipient BSA ratio was correlated with the glomerular filtration rate (GFR) of recipients at one and six months post-transplantation (r = 0.416, p < 0.001 and r = 0.381, p < 0.001, respectively). We found a difference in the graft function between recipients with a graft kidney volume/recipient BSA ratio of ≥90.9 mL/m(2) and those with a ratio of <90.9 mL/m(2) (p < 0.001). Multivariate analysis demonstrated that the graft kidney volume/recipient BSA ratio and donor age are independent predictors of recipient GFR at one and six months post-transplantation (p < 0.05). During living donor and recipient matching, both the potential volume of the donated kidney and the body size of recipient should be considered.

journal_name

Clin Transplant

journal_title

Clinical transplantation

authors

Lee JH,Won JH,Oh CK

doi

10.1111/j.1399-0012.2011.01502.x

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

E647-55

issue

6

eissn

0902-0063

issn

1399-0012

journal_volume

25

pub_type

杂志文章
  • Outcomes after simultaneous kidney-pancreas versus pancreas after kidney transplantation in the current era.

    abstract::Simultaneous pancreas and kidney (SPK) and pancreas after kidney (PAK) transplant are both potential options for diabetic ESRD patients. Historically, PAK pancreas graft outcomes were felt to be inferior to SPK pancreas graft outcomes. Little is known about outcomes in the modern era of transplantation. We analyzed ou...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/ctr.13732

    authors: Parajuli S,Arunachalam A,Swanson KJ,Aziz F,Garg N,Redfield RR,Kaufman D,Djamali A,Odorico J,Mandelbrot DA

    更新日期:2019-12-01 00:00:00

  • Kidney donor risk index is a good prognostic tool for graft outcomes in deceased donor kidney transplantation with short, cold ischemic time.

    abstract:BACKGROUND:We performed a retrospective cohort study to determine the prognostic value of standard criteria donor/expanded criteria donor (SCD/ECD) designation, with regard to one-yr GFR and graft survival rate, in a region with short, cold ischemic time (CIT), and how this designation compares with the kidney donor ri...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12318

    authors: Han M,Jeong JC,Koo TY,Jeon HJ,Kwon HY,Kim YJ,Ryu HJ,Ahn C,Yang J

    更新日期:2014-03-01 00:00:00

  • Risk factors for acute rejection in renal transplant recipients experiencing delayed graft function.

    abstract::Acute rejection (AR) superimposed upon delayed graft function (DGF) following renal transplantation worsens graft outcomes. However, risk factors for AR in patients displaying DGF remain unclear. In this study, 71 patients displaying DGF >/= 5 d were investigated. All received cyclosporine, adjunctive azathioprine or ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2008.00837.x

    authors: Moore J,Tan K,Cockwell P,Krishnan H,McPake D,Ready A,Mellor S,Hamsho A,Ball S,Lipkin G,Borrows R

    更新日期:2008-09-01 00:00:00

  • Multidetector CT angiography in living donor renal transplantation: accuracy and discrepancies in right venous anatomy.

    abstract::Multidetector computed tomography (MDCT) angiography is a reliable technique for assessing pre-operative renal anatomy in living kidney donors. The method has largely evolved into protocols that eliminate dedicated venous phase and instead utilize a combined arterial/venous phase to delineate arterial and venous anato...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2009.01193.x

    authors: Kulkarni S,Emre S,Arvelakis A,Asch W,Bia M,Formica R,Israel G

    更新日期:2011-01-01 00:00:00

  • Conundrums with FlowPRA beads.

    abstract::In 1969, a study by Patel and Terasaki persuaded the renal transplant community that a pre-transplant cross-match should always be performed between donor and recipient to detect HLA antibodies and prevent hyperacute allograft rejection. Although the role of the cross-match among nonsensitized patients is controversia...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.16.s7.3.x

    authors: Gebel HM,Harris SB,Zibari G,Bray RA

    更新日期:2002-01-01 00:00:00

  • Survival benefit of renal transplantation in octogenarians.

    abstract:BACKGROUND:Elderly patients are the fastest growing population requiring renal replacement therapy. As previous studies have shown a survival benefit of kidney transplantation compared to dialysis for end-stage renal disease, we sought to evaluate if this survival benefit extends to octogenarians. METHODS:This was a s...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.14074

    authors: Ravichandran BR,Sparkes TM,Masters BM,Thomas B,Demehin M,Bromberg JS,Haririan A

    更新日期:2020-11-01 00:00:00

  • The significance of subclinical rejection.

    abstract::Subclinical rejection (SCR) is quite common early following renal transplantation and decreases progressively with time. The immunological profile of the recipient, the immunosuppressive regimen used, and the occurrence of prior episodes of clinical acute rejection (AR) are all risk factors for SCR. SCR, in turn, is a...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-0012.2008.00888.x

    authors: El-Amm JM,Gruber SA

    更新日期:2009-03-01 00:00:00

  • Living donor evaluation and exclusion: the Stanford experience.

    abstract:BACKGROUND:The proportion of prospective living donors disqualified for medical reasons is unknown. The objective of this study is to delineate and quantify specific reasons for exclusion of prospective living donors from kidney donation. METHODS:All adult prospective kidney donors who contacted our transplant program...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1399-0012.2010.01336.x

    authors: Lapasia JB,Kong SY,Busque S,Scandling JD,Chertow GM,Tan JC

    更新日期:2011-09-01 00:00:00

  • Optimal timing for living-related liver transplantation in children.

    abstract:BACKGROUND:The pediatric end stage liver disease (PELD) score has been used widely to prioritize children awaiting cadaveric liver transplantation (LTx). To establish the objective parameter for optimal timing of living-related LTx (LRLTx), we have assessed our cases using the PELD score. METHODS:From 1997 to 2002, 24...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2004.00194.x

    authors: Kimura T,Hasegawa T,Sasaki T,Shimizu Y,Mushiake S,Fukuzawa M,Okada A

    更新日期:2004-10-01 00:00:00

  • Conversion from sirolimus to everolimus in kidney transplant recipients receiving a calcineurin-free regimen.

    abstract:BACKGROUND:Everolimus (EVL) and sirolimus (SRL) were introduced into immunosuppressive regimens, in an attempt to replace or reduce the dose of the nephrotoxic calcineurin inhibitors (CNI). In our institution, due to an administrative decision, conversion from SRL to EVL, was carried out, providing us the opportunity t...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2011.01446.x

    authors: Carvalho C,Coentrão L,Bustorff M,Patrício E,Sampaio S,Santos J,Oliveira G,Pestana M

    更新日期:2011-07-01 00:00:00

  • Blood glutathione as a marker of cardiac allograft vasculopathy in heart transplant recipients.

    abstract:BACKGROUND:Cardiac allograft vasculopathy (CAV) limits survival after heart transplantation (HTx). Between immunologic and non-immunologic factors, reactive oxygen species generation has been proposed as pathogenetic mechanism. This study was aimed at evaluating redox status in HTx recipients and verifying whether it c...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2005.00352.x

    authors: De Chiara B,Bigi R,Campolo J,Parolini M,Turazza F,Masciocco G,Frigerio M,Fiorentini C,Parodi O

    更新日期:2005-06-01 00:00:00

  • The effect of calcineurin inhibitors on endothelial function in renal transplant recipients.

    abstract::Endothelial dysfunction is of vital importance, as it may cause ischemia and dysfunction in various organs. Despite, this problem has been well documented in patients with end-stage renal disease (ESRD), there is not enough data considering this issue following renal transplantation. One of the potential causes of end...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2003.00030.x

    authors: Oflaz H,Turkmen A,Kazancioglu R,Kayacan SM,Bunyak B,Genchallac H,Erol B,Mercanoglu F,Umman S,Sever MS

    更新日期:2003-06-01 00:00:00

  • An analysis of pancreas transplantation outcomes based on age groupings--an update of the UNOS database.

    abstract:INTRODUCTION:Previously, increasing age has been a part of the exclusion criteria used when determining eligibility for a pancreas transplant. However, the analysis of pancreas transplantation outcomes based on age groupings has largely been based on single-center reports. METHODS:A UNOS database review of all adult p...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12407

    authors: Siskind E,Maloney C,Akerman M,Alex A,Ashburn S,Barlow M,Siskind T,Bhaskaran M,Ali N,Basu A,Molmenti E,Ortiz J

    更新日期:2014-09-01 00:00:00

  • Renal allograft loss due to proximal extension of ileofemoral deep venous thrombosis.

    abstract::Renal allograft recipients with thrombophilic (hypercoagulable) states are at higher risk for early allograft loss. Presumably, the combination of endothelial injury at surgery and thrombophilia predisposes to arterial or venous thrombosis. Of 270 consecutive renal transplants at our center one allograft failed second...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2002.02006.x

    authors: Ramirez PJ,Gohh RY,Kestin A,Monaco AP,Morrissey PE

    更新日期:2002-08-01 00:00:00

  • Orthotopic liver transplantation for adult-onset type II citrullinaemia.

    abstract::Citrullinaemia is a rare autosomal recessive disorder due to a deficiency of argininosuccinate synthetase (ASS). While the clinical course of the adult onset form (Type II) is unpredictable, many patients undergo sudden deterioration with progressive cerebral oedema. Two patients with Type II citrullinaemia were refer...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Kawamoto S,Strong RW,Kerlin P,Lynch SV,Steadman C,Kobayashi K,Nakagawa S,Matsunami H,Akatsu T,Saheki T

    更新日期:1997-10-01 00:00:00

  • Association between increased-risk donor social behaviors and recipient outcomes after heart transplantation.

    abstract:BACKGROUND:This study aims to investigate the association between social behaviors of increased-risk donors (IRD) and recipient outcomes after heart transplantation. METHODS:The United Network for Organ Sharing (UNOS) database was queried to identify patients who received a heart transplant between 2004 and 2015. Pati...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13787

    authors: Okoh AK,Chan O,Schultheis M,Gupta M,Shah A,Gold J,Russo MJ,Lee LY,Camacho M

    更新日期:2020-03-01 00:00:00

  • Pseudoaneurysm of the superior mesenteric artery with an arteriovenous fistula after simultaneous kidney-pancreas transplantation.

    abstract::Vascular complications remain a significant source of morbidity after pancreatic transplantation. We describe a pseudoaneurysm of the superior mesenteric artery (SMA) with an arteriovenous fistula (AVF) involving the SMA and the superior mesenteric vein (SMV) discovered and treated surgically in the second week after ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.1999.130310.x

    authors: Khan TF,Ciancio G,Burke GW 3rd,Sfakianakis GN,Miller J

    更新日期:1999-06-01 00:00:00

  • Interstitial alterations in renal cortex in acute tubular necrosis (ATN) post-renal transplantation and in patients with ATN not related to renal transplant.

    abstract:BACKGROUND:Abnormalities of renal function with long-term implications can persist after acute tubular necrosis (ATN), probably because of permanent loss of nephrons. Residual areas of fibrosis are also observed in the renal cortex post-ATN. In this study, we investigate the interstitial alterations post-ATN using hist...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1046/j.1399-0012.2003.00140.x

    authors: Moyses Neto M,Costa RS,Volpini RA,Garcia TM,Rodrigues FF,Coimbra TM

    更新日期:2004-04-01 00:00:00

  • Growth of a nation part I: impact of organ donor obesity on whole-organ pancreas transplantation.

    abstract::Obesity has reached epidemic proportions in the USA. Consequently, there are an increasing number of potential organ donors that are obese, but would otherwise be appropriate donors for pancreas transplantation (PTx). This is a retrospective study of all PTx performed at Indiana University between 2003 and 2009 (n = 3...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2011.01419.x

    authors: Fridell JA,Mangus RS,Taber TE,Goble ML,Milgrom ML,Good J,Vetor R,Powelson JA

    更新日期:2011-05-01 00:00:00

  • Eliminating international normalized ratio threshold for transfusion in pediatric patients with acute liver failure.

    abstract:INTRODUCTION:Transfusion protocols are not well-studied for pediatric patients with acute liver failure (ALF). This study evaluates the utility of an international normalized ratio (INR)-based transfusion threshold for these patients. METHODS:Forty-four ALF pediatric patients from 2009 to 2018 were reviewed and divide...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13819

    authors: Lee A,Mendoza J,Brubaker AL,Stoltz DJ,McKenzie R,Bonham CA,Esquivel CO,Gallo AE

    更新日期:2020-04-01 00:00:00

  • Attenuated early inflammatory response in solid organ recipients with COVID-19.

    abstract::Immunosuppression leaves transplanted patients at particular risk for severe acute respiratory syndrome 2 (SARS-CoV-2) infection. The specific features of coronavirus disease 2019 (COVID-19) in immunosuppressed patients are largely unknown and therapeutic experience is lacking. Seven transplanted patients (two liver, ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.14027

    authors: Bösch F,Börner N,Kemmner S,Lampert C,Jacob S,Koliogiannis D,Stangl M,Michel S,Kneidinger N,Schneider C,Fischereder M,Irlbeck M,Denk G,Werner J,Angele MK,Guba MO

    更新日期:2020-10-01 00:00:00

  • Significance of serial real-time PCR monitoring of EBV genome load in living donor liver transplantation.

    abstract:BACKGROUND:Quantitative analysis of the Epstein-Barr virus (EBV) genome has been recently reported to be helpful for early identification of EBV viremia which could reduce the risk of post-transplantation lymphoproliferative disorder (PTLD). AIM:To demonstrate the significance of serial monitoring of EBV genome load b...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2002.1o112.x

    authors: Matsukura T,Yokoi A,Egawa H,Kudo T,Kawashima M,Hirata Y,Tanaka H,Kagajo K,Wada H,Tanaka K

    更新日期:2002-04-01 00:00:00

  • Caring for the pregnant kidney transplant recipient.

    abstract::As fertility can be restored to normal soon after a kidney transplant, it is important for physicians caring for recipients to be able to inform the patient about the potential risks of pregnancy. Current opinion is that pregnancy can be successful if carried out under optimal circumstances, including stable allograft...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-0012.2011.01492.x

    authors: Concepcion BP,Schaefer HM

    更新日期:2011-11-01 00:00:00

  • Pediatric transplantation in Europe during the COVID-19 pandemic: Early impact on activity and healthcare.

    abstract::The current pandemic SARS-CoV-2 has required an unusual allocation of resources that can negatively impact chronically ill patients and high-complexity procedures. Across the European Reference Network on Pediatric Transplantation (ERN TransplantChild), we conducted a survey to investigate the impact of the COVID-19 o...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ctr.14063

    authors: Doná D,Torres Canizales J,Benetti E,Cananzi M,De Corti F,Calore E,Hierro L,Ramos Boluda E,Melgosa Hijosa M,Garcia Guereta L,Pérez Martínez A,Barrios M,Costa Reis P,Teixeira A,Lopes MF,Kaliciński P,Branchereau S,Boyer O

    更新日期:2020-10-01 00:00:00

  • A calcineurin antagonist-free induction/maintenance strategy for immunosuppression in elderly recipients of renal allografts from elderly cadaver donors: long-term results from a prospective single centre trial.

    abstract:BACKGROUND:With the aim to improve the inferior outcomes in elderly recipients of kidneys from elderly cadaver donors, we applied and investigated a therapeutic regimen consisting of calcineurin inhibitor (CNI)-free, mycophenolate mofetil (MMF)-based immunosuppressive (i.s.) induction/maintenance protocol. In this arti...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1399-0012.2005.00309.x

    authors: Arbogast H,Hückelheim H,Schneeberger H,Illner WD,Tarabichi A,Fertmann J,Wimmer CD,Hillebrand GF,Mistry-Burchardi N,Thomae R,Acikgöz A,Land W

    更新日期:2005-06-01 00:00:00

  • Predicting and preventing readmissions in kidney transplant recipients.

    abstract::A lack of research exploring post-transplant process optimization to reduce readmissions and increasing readmission rates at our center from 2009 to 2013 led to this study, aimed at assessing the effect of patient and process factors on 30-d readmission rates after kidney transplantation. This was a retrospective case...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12748

    authors: Covert KL,Fleming JN,Staino C,Casale JP,Boyle KM,Pilch NA,Meadows HB,Mardis CR,McGillicuddy JW,Nadig S,Bratton CF,Chavin KD,Baliga PK,Taber DJ

    更新日期:2016-07-01 00:00:00

  • Microemulsion technology in the reformulation of cyclosporine: the reason behind the pharmacokinetic properties of Neoral.

    abstract::Management of transplant patients receiving cyclosporine therapy is complicated by interpatient and intrapatient variability in pharmacokinetic parameters caused by the drug's unpredictable bioavailability. Cyclosporine, a highly lipophilic cyclic polypeptide, has recently been reformulated using a microemulsion deliv...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:

    authors: Ritschel WA

    更新日期:1996-08-01 00:00:00

  • No apparent impact of increased post-operative blood glucose levels on clinical outcome in kidney transplant recipients.

    abstract:BACKGROUND:Our objective is to evaluate whether hyperglycemia in the first 48 h after renal transplantation is independently associated with rejection, post-operative infection and post-transplant diabetes mellitus (PTDM) in a retrospective cohort study. METHODS:Patients who received a renal transplant in our hospital...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2008.00910.x

    authors: van den Berg TJ,Bogers H,Vriesendorp TM,Surachno JS,DeVries JH,ten Berge IJ,Hoekstra JB

    更新日期:2009-03-01 00:00:00

  • Liver transplantation without isoniazid prophylaxis for recipients with a history of tuberculosis.

    abstract::Tuberculosis remains one of the most serious infections after organ transplantation. Isoniazid prophylaxis for liver transplant recipients with a history of tuberculosis is generally recommended. However, its benefit is controversial because of potential hepatotoxicity of isoniazid. It is crucial to determine appropri...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2006.00630.x

    authors: Nagai S,Fujimoto Y,Taira K,Egawa H,Takada Y,Kiuchi T,Tanaka K

    更新日期:2007-03-01 00:00:00

  • Itraconazole for the treatment of pulmonary aspergillosis in heart transplant recipients.

    abstract::The objective of this study was to evaluate the effects of itraconazole as a first choice drug in the treatment of pulmonary aspergillosis in heart transplant recipients. Heart transplant recipients suffering from invasive pulmonary aspergillosis were included in this study. Group 1 included 4 patients treated with i....

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Nanas JN,Saroglou G,Anastasiou-Nana MI,Kostis EB,Petrochilou-Paschou VP,Kontoyannis DA,Stamatelopoulos SF,Moulopoulos SD

    更新日期:1998-02-01 00:00:00