The stoichiometry of expression of protein components of the stimulatory adenylyl cyclase cascade and the regulation of information transfer.

Abstract:

:Quantitative analysis of the proteins which compromise the stimulatory arm of the adenylyl cyclase cascade indicate that the adenylyl cyclase catalytic component is usually the least highly expressed. The effects on both potency of agonist ligands and maximal output resulting from targetted alterations in expression levels of each element of this cascade are discussed.

journal_name

Cell Signal

journal_title

Cellular signalling

authors

Milligan G

doi

10.1016/0898-6568(95)02034-9

subject

Has Abstract

pub_date

1996-02-01 00:00:00

pages

87-95

issue

2

eissn

0898-6568

issn

1873-3913

pii

0898656895020349

journal_volume

8

pub_type

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