Abstract:
:The purpose of the study was to assess the relation between the simultaneous exposure to alcohol and consumption of micronutrients that have protective properties against colorectal cancer. A hospital-based case-control study of colorectal cancer was carried out between January 1998 and November 1999 at the University Hospital in Krakow, Poland. In total, 180 incident cases of colorectal cancer, confirmed by histopathology, were recruited and an equal number of controls, individually matched by gender and age (+/-5 y), were chosen amongst patients with no history of cancer. A food-frequency questionnaire for 148 food items, combined with the quantity of foods eaten, was used to assess the normal dietary pattern. The data confirmed the reported inverse association between the intake of retinol, thiamine, or antioxidant micronutrients (vitamins C, E) and the occurrence of colorectal cancer. Alcohol intake was found to be an important risk factor for this cancer site, and the risk escalated in parallel with increased intake of retinol, carotene, vitamins C and E, but with high consumption of alcohol ran a noticeably high risk of colorectal cancer (OR= 6.79; 95% CI: 2.08-22.18). The risk was markedly lower, however, among alcohol drinkers who reported a high intake of micronutrients (OR = 1.35; 95% CI: 0.39-4.67). The data suggest that a combination of high consumption of alcohol and low intake of retinol and antioxidant vitamins may considerably increase the risk of colorectal cancer.
journal_name
Rev Environ Healthjournal_title
Reviews on environmental healthauthors
Jedrychowski W,Steindorf K,Popiela T,Wahrendorf J,Tobiasz-Adamczyk B,Kulig J,Penar Adoi
10.1515/reveh.2001.16.3.213subject
Has Abstractpub_date
2001-07-01 00:00:00pages
213-22issue
3eissn
0048-7554issn
2191-0308journal_volume
16pub_type
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pub_type: 杂志文章,评审
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2015-0017
更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1515/reveh-2020-0041
更新日期:2020-09-18 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2012-0028
更新日期:2012-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.2001.16.4.233
更新日期:2001-07-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2015-0036
更新日期:2016-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1515/reveh-2015-0049
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2015-0042
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pub_type: 杂志文章,评审
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2014-0010
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2020-0020
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh.1996.11.1-2.85
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2016-0030
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journal_title:Reviews on environmental health
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doi:10.1515/reveh-2015-0011
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doi:10.1515/reveh-2015-0077
更新日期:2016-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1515/reveh-2015-0003
更新日期:2015-01-01 00:00:00