Abstract:
:1,4-Dichlorobenzene (1,4-DCB) is a wide-spread environmental contaminant and well-described hepatotoxicant for rats and mice. The prolonged oral or inhalation exposure to 1,4-DCB is associated with an increased frequency of hepatic tumors in mice, but not in rats. Evidence is lacking of direct genotoxicity with 1,4-DCB or its metabolites, and no generally accepted mechanism has been found to account for the increased numbers of 1,4-DCB-induced hepatic tumors in mice. No information is available on the carcinogenic effects of 1,4-DCB in humans. Here we consider evidence that the biotransformation of 1,4-DCB to substituted hydroquinone species contributes to hepatic adenoma and carcinoma formation in mouse liver. This phenomenon has implications for human carcinogenesis.
journal_name
Rev Environ Healthjournal_title
Reviews on environmental healthauthors
Muller Mdoi
10.1515/reveh.2002.17.4.279subject
Has Abstractpub_date
2002-10-01 00:00:00pages
279-90issue
4eissn
0048-7554issn
2191-0308journal_volume
17pub_type
杂志文章,评审abstract::The indoor environment is a major source of human exposure to pollutants. Some pollutants can have concentrations that are several times higher indoors than outdoors. Prolonged exposure may lead to adverse biologic effects, even at low concentrations. Several studies done in Malaysia had underlined the role of indoor ...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2014-0065
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journal_title:Reviews on environmental health
pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2019-0012
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journal_title:Reviews on environmental health
pub_type: 杂志文章
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更新日期:2004-07-01 00:00:00
abstract::Protecting the public from waterborne diseases is an environmental health responsibility that every government worldwide must deal with. Canada's recent experience with waterborne outbreaks has brought the effectiveness of its water-monitoring and treatment systems under scrutiny. This paper focuses on microbial water...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
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更新日期:2008-04-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2018-0058
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journal_title:Reviews on environmental health
pub_type: 杂志文章
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abstract::Pesticides having a high adverse effect on the health and environment of inhabitants of the Mexican Republic were studied to establish the main parameters to bear in mind for their use and application. The investigation showed that Mexico is the agricultural zone with the highest health damage to its population from p...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.2000.15.4.399
更新日期:2000-10-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2015-0036
更新日期:2016-03-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2015-0061
更新日期:2016-03-01 00:00:00
abstract::Population explosion, to the tune of -7.2 billion, along with excessive use of natural resources and a variety of anthropogenic activities, has resulted in large-scale contamination of the environment, especially the soil and groundwater.Contamination in the environment is an ever-increasing phenomenon, and often, reg...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2012-0028
更新日期:2012-01-01 00:00:00
abstract::The toxicity of water pollutants to aquatic animals is reviewed, with particular emphasis on methods for measuring lethal toxicity, factors influencing toxicity, the measurement of chronic and sublethal toxicity, and the role of toxicological data in formulating water quality standards. Methods for measuring lethal to...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-1989-1-407
更新日期:1989-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2016-0040
更新日期:2016-12-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2015-0003
更新日期:2015-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.2001.16.2.81
更新日期:2001-04-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2016-0039
更新日期:2017-03-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2019-0049
更新日期:2019-12-18 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.1997.12.1.43
更新日期:1997-01-01 00:00:00
abstract::Mercury (Hg), also known as quick silver, is an essential constituent of dental amalgam. It is a toxic substance of global concern. Children are more at risk from mercury poisoning which affects their neurological development and brain. In the past, a number of studies at dental sites in many countries have been carri...
journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2014-0010
更新日期:2014-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2012-0035
更新日期:2013-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2015-0049
更新日期:2016-03-01 00:00:00
abstract::Exposure to extremely low frequency magnetic fields (ELF-MF) and electric shocks occurs in many workplaces and occupations but it is unclear whether any of these exposures cause Amyotrophic lateral sclerosis (ALS). The aim of this systematic review and meta-analysis is to explore whether occupational exposure to ELF-M...
journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2020-0041
更新日期:2020-09-18 00:00:00
abstract::Lead exposure is associated with impaired neurodevelopment among children. House dust is recognized as one of the important secondary sources of lead exposure in children. We assessed the relationship between lead contamination in house dust and blood lead level in Pakistani children. We investigated lead contaminatio...
journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2020-0020
更新日期:2020-09-25 00:00:00
abstract::Purpose Endocrine-related diseases and disorders are on the rise globally. Synthetically produced environmental chemicals (endocrine-disrupting chemicals (EDCs)) mimic hormones like oestrogen and alter signalling pathways. Endometriosis is an oestrogen-dependent condition, affecting 10-15% of women of the reproductive...
journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2020-0046
更新日期:2020-09-09 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.2007.22.4.313
更新日期:2007-10-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2014-0016
更新日期:2014-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:
更新日期:1980-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh.2008.23.1.83
更新日期:2008-01-01 00:00:00
abstract::Phytoremediation is the direct use of living green plants to degrade, contain, or render harmless various environmental contaminants, including recalcitrant organic compounds or heavy metals. The methods involved include phytoextraction, direct phytodegradation, rhizofiltration, phytovolatilization or formation of art...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:
更新日期:2004-01-01 00:00:00