Abstract：
BACKGROUND:The etiology of Inflammatory Bowel Diseases, Crohn's disease (CD) and ulcerative colitis (UC), is unknown. These diseases have a higher incidence in industrialized countries and their pathogenesis involves an over-reaction of the immune system. A genetic factor is believed to predispose to the development of chronic inflammation in response to an unidentified stimulus. Exposure to infections in childhood may modulate future immune responses. Parasitosis, particularly Schistosomiasis, stimulate Th2 immune responses. It has been hypothesized that the absence of these parasitic infections, as seen in economically developed countries, favors a Th1 response that may result in the clinical appearance of Crohn's disease later in life. OBJECTIVE:To determine the prevalence of Schistosoma mansoni antibodies in Puerto Ricans with Inflammatory Bowel Disease and controls. METHODS:Serum from 92 Puerto Ricans with IBD and 106 controls was screened for S. mansoni adult microsomal antigens (MAMA) using the FAST:ELISA assay. Those positive were confirmed with an enzyme-linked immunoelectrotransfer blot test. RESULTS:Seven serum samples (3 UC and 4 controls) were positive for S. mansoni antibodies. There was no significant difference between groups in gender, municipality of origin or seroprevalence of Schistosomiasis. The control group was slightly older than the IBD group. CONCLUSIONS:Our study did not demonstrate an inverse relation between Schistosomiasis and IBD. However, the decreasing prevalence of Schistosomiasis in the general population of Puerto Rico may account for this result.
journal_name
P R Health Sci Jjournal_title
Puerto Rico health sciences journalauthors
Torres EA,Acosta H,Cruz M,Weinstock J,Hillyer GVsubject
Has Abstractpub_date
2001-09-01 00:00:00pages
211-4issue
3eissn
0738-0658issn
2373-6011journal_volume
20pub_type
杂志文章abstract：:DNA microarray is a technology that simultaneously evaluates quantitative measurements for the expression of thousands of genes. DNA microarrays have been used to assess gene expression between groups of cells of different organs or different populations. In order to understand the role and function of the genes, one ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2009-06-01 00:00:00
abstract：:Exposure to lead in children living on a former landfill in Vega Baja-Puerto Rico, a United States Environmental Protection Agency (USEPA) designated Superfund Site, is a major health concern. Direct contact with lead-contaminated soil is considered a major exposure source. However, there is a lack of information rega...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2003-06-01 00:00:00
abstract：:This brief celebration of the work of Francisco Guerra (1916-2011) highlights his role as mentor for an international community, his study of local events in the context of global developments, and his contributions to the understanding of the medical history of Puerto Rico. A selective review of Francisco Guerra's me...
journal_title：Puerto Rico health sciences journal
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2012-06-01 00:00:00
abstract：:Insulin-dependent diabetes mellitus (IDDM) is a chronic health condition that affects 18 of every 100,000 Puerto Rican youth. Few research studies have been performed on the problems that youth with diabetes encounter and how they are related to adherence to treatment and adequate metabolic control. Adequate metabolic...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2006-12-01 00:00:00
abstract：:Seventy two partial subperiosteal implants were inserted in 52 patients. Thirty six of these implants had a classical design in which the submerged structure had thick primary and secondary connectors. Thirty six implants had a newly designed submerged structure consisting of long and thin primary connectors with groo...
journal_title：Puerto Rico health sciences journal
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：BACKGROUND:Low back pain is one of the most frequent work related injuries in all occupations. Back school programs are therapeutic interventions directed towards treatment, prevention and rehabilitation of backaches. The purpose of this study was to (1) evaluate the test-retest reliability of the modified version of t...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
abstract：:Diagnosing cancer using microarray analysis to study differential gene expression has been a recent focus of intense research Although several very sophisticated analysis tools have been developed with this aim in mind, it still remains a challenge to keep these methods free of parametric adjustments as well as mainta...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：:The therapy of chronic myeloid leukemia (CML), characterized by the presence of the Philadelphia chromosome in the clonal hematopoietic stem cells, has changed dramatically in the last year with the development of a specific inhibitor of the BCR-ABL tyrosine kinase. This medication, STI571 or imatinib, was recently ap...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVE:This study aimed to assess the role of gender on HIV/AIDS stigma among 507 medical students in Puerto Rico. METHODS:A secondary data analysis was performed with baseline measurements of a controlled randomized study. RESULTS:Unadjusted analyses showed that the overall multivariate test for gender was signif...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：:Folate deficiency is one of today's most common vitamin deficiencies in women. Women who consume a low level of folate during pregnancy are at risk for poor pregnancy outcomes including neural tube defects (NTD). However, other factors such as heredity, social class, maternal age, birth order, maternal diet, length of...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：1997-12-01 00:00:00
abstract：OBJECTIVE:Colorectal cancer (CRC) is among the most common cancers in Puerto Rico. Few studies have correlated clinical and pathological variables with the overall survival of CRC patients in Puerto Rico. We report the clinical and pathological characteristics of patients who underwent surgical resection at a community...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:To determine the IgE reactivity against recombinant protein Blo t 1 from the dust mite Blomia tropicalis (Bt) using serum from patients with positive skin test to this mite and to investigate the cross-reactivity between Bt and Dermatophagoides pteronyssinus. BACKGROUND:Dust mites have an important role as i...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2003-12-01 00:00:00
abstract：:Deficient mydriasis of diverse etiology renders extracapsular cataract extraction and posterior chamber intraocular lens implantation technically difficult. Several techniques are available to improve surgical results when this problem is present. We have used multiple sphincterotomies in 6 patients with narrow pupils...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:Advances in the understanding of chondrocytes and the synovial membrane as targets of and participants in the inflammatory process in articular joints have provided insights into the role of inflammation in cartilage and subchondral bone injury in rheumatic diseases. Reports that describe the inflammatory cellular inf...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2017-09-01 00:00:00
abstract：:Genital human papillomavirus (HPV) infection is one of the most commonly diagnosed sexually transmitted infections world-wide. Over the last two decades, research has established a strong causal link between specific types of HPV infection and cancer, particularly cervical, anal, vulvar/vaginal, penile, and oropharyng...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2010-09-01 00:00:00
abstract：:Hypokalemic periodic paralysis (hypoKPP) is a clinical entity characterized by recurrent skeletal muscle paralysis due to a decrease in serum potassium levels; hypoKPP can have either a primary (familial) or a secondary cause. One of the secondary causes of hypoKPP is distal renal tubular acidosis (dRTA). Distal renal...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2017-12-01 00:00:00
abstract：:This paper examines the characteristics of youngsters in drug treatment who volunteer for AIDS testing in comparison to those who do not. HIV Antibodies testing was offered on a voluntary basis to a sample of 250 Puerto Rican youngsters enrolled in three ambulatory drug treatment centers in 1991. Sixty-six percent of ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：:Thymidine kinase is a key enzyme responsible for the activation of several anticancer and antiviral drugs. As the first enzyme in the salvage pathway of thymidine, it is regulated by the feedback inhibition exerted by the end-product of the pathway, namely thymidine 5'-triphosphate. 5'-Aminothymidine is a non-toxic an...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：1994-03-01 00:00:00
abstract：OBJECTIVE:Burnout exerts a significant negative influence on job performance, especially in such difficult jobs as those to be found in the health care industry. This research aimed to evaluate the association between 3 dimensions of burnout and demographic factors among the medical staff working in all of the hospital...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:The present study was performed to detect cancer risk of the midwifes and nurses playing central role in raising awareness in the society using Gail's model. MATERIALS AND METHODS:Sample of the present cross sectional study consists of 750 volunteer midwifes and nurses in 2016. Breast cancer risk was calcula...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2018-06-01 00:00:00
abstract：:Hypopharyngeal carcinoma as a subsite of head and neck cancer, carries with it the lowest 5-year relative survival rate. Treatment of hypopharyngeal cancer relies on single therapy or multimodality treatment: surgery, radiation and/or chemotherapy. When surgical intervention is chosen, the type of operation depends on...
journal_title：Puerto Rico health sciences journal
pub_type：
doi：
更新日期：2020-03-01 00:00:00
abstract：:Aspiration of foreign bodies is more common in children than adults. The clinical and radiological findings between these two age groups are different. It is a clinical diagnosis often overlooked in adults. We hereby present an elderly male patient who was referred to us due to a one year history of hemoptysis. He was...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：:Although regeneration in the peripheral nervous system (PNS) after injury is robust, regeneration in the central nervous system (CNS) is abortive. The results from differences in the balance of regeneration inhibiting and promoting factors, which in the CNS is skewed toward inhibition while in the PNS it is skewed tow...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2000-09-01 00:00:00
abstract：:Rat gene 33 (g33) mRNA has a widespread tissue distribution. Insulin and various agents such as glucocorticoids, phorbol esters and plant lectins regulate G33 expression in rat hepatoma cells. The regulation of g33 by insulin and a phorbol ester was examined in two Chinese Hamster ovary (CHO) cell lines, CHO-T cells (...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:This study aims to determine the prevalence of Mycobacterium tuberculosis infection and its association with HIV and other health risk factors among drug users. A sample of 716 IDUs and crack users were enrolled from community sites. Consenting subjects were tested for HIV serum antibody status. Drug users with an unk...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:Renal cell carcinoma is the most common cancer of the kidney and is among the tumors that are the most resistant to systemic therapy. Until recently, long term survival of this disease when it was not confined to the kidney was dismal, with the use of drugs such as interleukin-2 resulting in a 5-year survival rate of ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:A cross-sectional study was conducted (2012-2013) to evaluate the prevalence of 1) malocclusion and 2) occlusal characteristics in 13- to 18-yearold adolescents in San Juan, Puerto Rico (PR) from selected high schools in the municipality of San Juan. METHODS:The study sample consisted of 155 adolescents. The...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2017-06-01 00:00:00
abstract：:The University of Puerto Rico School of Pharmacy was initially established as the Department of Pharmacy at the Río Piedras Campus on September 22, 1913, being the first healthcare program founded in Puerto Rico. The history of the School of Pharmacy reveals a remarkable evolution over a 100 years period in order to r...
journal_title：Puerto Rico health sciences journal
pub_type： 历史文章,杂志文章
doi：
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:The recent FDA approval of non-prescription sales of Plan B, an emergency contraceptive method to those 18 years old and over, gives a prominent role to pharmacists in providing timely access to emergency contraception (EC). While this decision affects Puerto Rico, no studies on non-prescription EC in Puerto...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：:Candida is the fourth most common cause of nosocomial bloodstream infections (BSI), being Candida albicans the most common species. This study evaluated the distribution of Candida spp isolates at a tertiary care medical center. The associated factors and outcome of patients with candidemia at the Puerto Rico Medical ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
