Abstract：
:Advances in the understanding of chondrocytes and the synovial membrane as targets of and participants in the inflammatory process in articular joints have provided insights into the role of inflammation in cartilage and subchondral bone injury in rheumatic diseases. Reports that describe the inflammatory cellular infiltration of synovial membranes in patients with osteoarthritis, studies that associate cartilage structural injury with synovial membrane inflammatory status, the development of new imaging modalities that quantitatively measure synovial membrane inflammation and basic science advances that explore inflammatory pathways in the synovial cavity all suggest that inflammation plays an important role in cartilage injury in osteoarthritis. As a result there is a shift in the notion that osteoarthritis is a disease caused merely by mechanical forces that increase joint loading. In response to this change in the current paradigm, innovative treatments involving the use of medications that modify the body's immune response (i.e., biologic and disease- modifying agents) are being studied. Implications for the population of Puerto Rico are discussed herein.
journal_name
P R Health Sci Jjournal_title
Puerto Rico health sciences journalauthors
Vilá Ssubject
Has Abstractpub_date
2017-09-01 00:00:00pages
123-129issue
3eissn
0738-0658issn
2373-6011journal_volume
36pub_type
杂志文章,评审abstract：OBJECTIVE:To describe the respiratory pathogens found in the bronchoalveolar lavage of a Puerto Rican population infected with the human immunodeficiency virus (HIV). BACKGROUND:Empirical treatment is an accepted strategy for management of HIV-related pneumonia, but it is usually recommended for countries that have kn...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVE:This study intends to determine the prevalence of multidrug resistant (MDR) infections by A. baumannii, K. pneumoniae and P. aeruginosa in a tertiary care teaching hospital intensive care unit (ICU) in San Juan, PR, estimate the mortality rate and compare the morbidity and mortality differences among those tr...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVE:To evaluate and compare the efficacy in obtaining an adequate endocervical sampling using the endocervical brush and the endocervical curettage. METHODS:Analysis of the cytology and histology of samples obtained from patients referred to the University of Puerto Rico School of Medicine Tertiary Care Center A...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：:Osteoporosis in men was not recognized as a major health problem until recently, and increased research in this area resulted in the approval of alendronate for the treatment of osteoporosis in men at the beginning of this decade. Low bone mineral density (BMD) has been demonstrated to be a strong predictor of fractur...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2005-06-01 00:00:00
abstract：:Endothelial cell proliferation and differentiation into blood capillaries (i.e., angiogenesis) are essential for growth and development, wound healing, osetogenesis, etc. But abnormal angiogenesis during tumor progression could lead to serious consequences. Angiogenesis is a complex biochemical process, and is often d...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:Surveillance for emerging diseases is critically dependent on four factors: reporting methods, case definition, laboratory diagnosis, and knowledge of the disease among health-care professionals. The dengue hemorrhagic fever (DHF) surveillance system in Puerto Rico collects patient data from three sources: dengue case...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：:Renal cell carcinoma is the most common cancer of the kidney and is among the tumors that are the most resistant to systemic therapy. Until recently, long term survival of this disease when it was not confined to the kidney was dismal, with the use of drugs such as interleukin-2 resulting in a 5-year survival rate of ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2011-06-01 00:00:00
abstract：:Although regeneration in the peripheral nervous system (PNS) after injury is robust, regeneration in the central nervous system (CNS) is abortive. The results from differences in the balance of regeneration inhibiting and promoting factors, which in the CNS is skewed toward inhibition while in the PNS it is skewed tow...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2000-09-01 00:00:00
abstract：:This is a case report of a patient who developed a nodule in one foot, which upon biopsy, was diagnosed as tungiasis, a cutaneous infestation caused by a human flea. The natural life cycle, clinical and pathological expressions are discussed. ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2007-12-01 00:00:00
abstract：:We tested a dietary supplement formulated with a synergistic combination of vitamins, minerals, herbals in a group of 15 patients with uncontrolled diabetes type II. The supplement was given for 30 days. Fasting blood glucose was measured prior to the supplementation and at the end of the 30 days treatment period. Blo...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND:The etiology of Inflammatory Bowel Diseases, Crohn's disease (CD) and ulcerative colitis (UC), is unknown. These diseases have a higher incidence in industrialized countries and their pathogenesis involves an over-reaction of the immune system. A genetic factor is believed to predispose to the development of...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：OBJECTIVE:To determine the frequency of pediatric brain tumors treated at the University Pediatric Hospital of Puerto Rico over a 6-year period and examine the demographic data and tumor histology of patients in different age groups. METHODS:A retrospective study was undertaken at the University Pediatric Hospital. We...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：:Hypokalemic periodic paralysis (hypoKPP) is a clinical entity characterized by recurrent skeletal muscle paralysis due to a decrease in serum potassium levels; hypoKPP can have either a primary (familial) or a secondary cause. One of the secondary causes of hypoKPP is distal renal tubular acidosis (dRTA). Distal renal...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2017-12-01 00:00:00
abstract：:Primary hepatic actinomycosis is an uncommon entity. We report the case of a young man with past history of an appendectomy who presented with fever, weight loss and a liver mass that was initially suspected to be neoplastic. Percutaneous liver biopsy revealed actinomyces-like organisms. The patient was treated with i...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：1992-04-01 00:00:00
abstract：OBJECTIVE:Burnout exerts a significant negative influence on job performance, especially in such difficult jobs as those to be found in the health care industry. This research aimed to evaluate the association between 3 dimensions of burnout and demographic factors among the medical staff working in all of the hospital...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2015-12-01 00:00:00
abstract：INTRODUCTION:Incidental adrenal tumors are commonly benign, but reports demonstrate that if the characteristics of the tumor are not clear, on images surgery is the procedure of choice. Our objective through this case is to show that laparoscopic adrenalectomy is a safe approach for adrenal incidental tumor regardless ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：:We have studied the spontaneous interaction with small, inedible objects by group-living Saimiri. Twenty-one animals living in a large outdoor enclosure were presented with a set of 10 novel objects of diverse materials, colors, sizes, and shapes. We have used a sampling technique to record the number of monkeys inter...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1985-12-01 00:00:00
abstract：:DNA microarray is a technology that simultaneously evaluates quantitative measurements for the expression of thousands of genes. DNA microarrays have been used to assess gene expression between groups of cells of different organs or different populations. In order to understand the role and function of the genes, one ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2009-06-01 00:00:00
abstract：:Candida is the fourth most common cause of nosocomial bloodstream infections (BSI), being Candida albicans the most common species. This study evaluated the distribution of Candida spp isolates at a tertiary care medical center. The associated factors and outcome of patients with candidemia at the Puerto Rico Medical ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
abstract：:Alzheimer's Disease. The untold story. After considering the potential relationship between amyloid deposits and myxedematous infiltrations, the hypothesis is formulated that Alzheimer's disease may be due to functional hypothyroidism and may thus respond to thyroid therapy. ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：OBJECTIVE:The present study was performed to detect cancer risk of the midwifes and nurses playing central role in raising awareness in the society using Gail's model. MATERIALS AND METHODS:Sample of the present cross sectional study consists of 750 volunteer midwifes and nurses in 2016. Breast cancer risk was calcula...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2018-06-01 00:00:00
abstract：:Hypopharyngeal carcinoma as a subsite of head and neck cancer, carries with it the lowest 5-year relative survival rate. Treatment of hypopharyngeal cancer relies on single therapy or multimodality treatment: surgery, radiation and/or chemotherapy. When surgical intervention is chosen, the type of operation depends on...
journal_title：Puerto Rico health sciences journal
pub_type：
doi：
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:Dental caries is one of the most prevalent chronic diseases in children. Currently, no data are available on dental caries prevalence in the Dominican Republic. The purpose of this study was to estimate the prevalence of dental caries in schoolattending 12-year-olds in San Pedro de Macorís, Dominican Republic...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2020-06-01 00:00:00
abstract：:Breastfeeding has experienced a surge in Puerto Rico thanks to the efforts of many women, as well as governmental, non-governmental and private organizations. Among the aspects which can affect the initiation, establishment and maintenance of successful breastfeeding one finds potential ethical conflicts among health ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：:Atherosclerosis is the most frequent cause of ischemic heart disease and cerebrovascular disorders. The condition is the leading cause of death in Western societies. At the core of this condition is the atherosclerotic plaque. It is within the structure of this lesion that multiple biochemical and cellular processes i...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:to estimate the prevalence of pit and fissure sealants on first permanent molars in twelve year olds living in Puerto Rico and to further evaluate dental sealant prevalence by (1) urban/rural and public/private school status as well as (2) gender; DESIGN:population-based, cross-sectional study. SETTING:publ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
abstract：:The type of glass used to fabricate patch pipettes influences the kinetic properties of single-channel currents activated by acetylcholine in Xenopus myocytes. In patches formed with hard glass pipettes, the opening rate decreased in a time-dependent manner. Such decrease was most pronounced for the low conductance ch...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1988-08-01 00:00:00
abstract：:Insulin-dependent diabetes mellitus (IDDM) is a chronic health condition that affects 18 of every 100,000 Puerto Rican youth. Few research studies have been performed on the problems that youth with diabetes encounter and how they are related to adherence to treatment and adequate metabolic control. Adequate metabolic...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2006-12-01 00:00:00
abstract：OBJECTIVE:Breast asymmetries have a high prevalence among women requesting breast augmentation. However, the prevalence of breast asymmetries in women undergoing other types of breast surgeries is not known. METHODS:The breast measurements of consecutively women evaluated for plastic surgery of the breast, but without...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2018-12-01 00:00:00
abstract：:The physical parameters of nuclear size and granularity, and the biological parameters of nuclear protein and DNA content were simultaneously measured by the flow cytometric analysis of mitogen-activated Rhesus monkey lymphocytes. These experiments were performed with the purpose of establishing baseline values for mi...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
