Abstract:
:Folate deficiency is one of today's most common vitamin deficiencies in women. Women who consume a low level of folate during pregnancy are at risk for poor pregnancy outcomes including neural tube defects (NTD). However, other factors such as heredity, social class, maternal age, birth order, maternal diet, length of time between pregnancies, maternal zinc deficiency, use of anticonvulsant drugs, abnormal homocysteine metabolism and the use of oral contraceptives, have also been implicated as causes of NTD. Animal studies have shown that fetuses are highly dependent on the folate status of the mother. In addition, several retrospective and prospective human studies have provided evidence that folate lowers the incidence of NTD.
journal_name
P R Health Sci Jjournal_title
Puerto Rico health sciences journalauthors
González MJ,Schmitz KJ,Matos MI,López D,Rodríguez JR,Gorrín JJsubject
Has Abstractpub_date
1997-12-01 00:00:00pages
387-93issue
4eissn
0738-0658issn
2373-6011journal_volume
16pub_type
杂志文章,评审abstract::DNA microarray is a technology that simultaneously evaluates quantitative measurements for the expression of thousands of genes. DNA microarrays have been used to assess gene expression between groups of cells of different organs or different populations. In order to understand the role and function of the genes, one ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2009-06-01 00:00:00
abstract::This is the case of an 11-year-old girl who presented with a right adnexal mass and vague abdominal symptoms since seven months prior to her hospital admission for surgery. CT-scan and sonographic images were those of a benign lesion, probably ovarian torsion or infarction. Serum tumoral markers were normal. A right s...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:People with type 1 diabetes (T1D) may experience significant changes in their daily routines due to this condition, which frequently results in depressive symptoms and the deterioration of their quality of life. We examined the factors associated with suicidal ideation (SI) and diabetes-related quality of lif...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2018-03-01 00:00:00
abstract::The University of Puerto Rico School of Pharmacy was initially established as the Department of Pharmacy at the Río Piedras Campus on September 22, 1913, being the first healthcare program founded in Puerto Rico. The history of the School of Pharmacy reveals a remarkable evolution over a 100 years period in order to r...
journal_title:Puerto Rico health sciences journal
pub_type: 历史文章,杂志文章
doi:
更新日期:2013-12-01 00:00:00
abstract::Atrial fibrillation (AF) is the most common sustained arrhythmia in adults. It is a significant public health problem in the United States where it affects 2.2 million Americans and almost 10% of the population older than 80 years. It should be emphasized that the prevalence of AF increases with advancing age and with...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2004-12-01 00:00:00
abstract::A retrospective review was performed from November 2011 through June 2012 in 49 stable patients receiving ambulatory hemodialysis at the dialysis unit of the University Hospital in San Juan. Measurements of serum phosphate, serum calcium (corrected to albumin levels), intact parathyroid hormone (PTH), and pulse pressu...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:Present evidence-based recommendations on the use of biochemical markers of bone turnover in the management of osteoporosis. METHODS:The English literature from 1999 to 2005 was reviewed by using data sources from MEDLINE. RESULTS:Measurement of biochemical markers of bone turnover helps us identify a high ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2007-06-01 00:00:00
abstract::Although injection drug use (IDU) is the major risk category for HIV infection in Puerto Rico and injection drug users start their drug injection careers very young, there is little information related to drug injection patterns of young IDUs. In this paper we report on factors found to be associated with HIV seroposi...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::Breastfeeding mothers need orientation and help in order to succeed with breastfeeding. Lack of support from health professionals and societal barriers result in a median duration of breastfeeding in Puerto Rico of only 3 weeks. A telephone warm line at our breastfeeding clinic tries to provide some much-needed suppor...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of hypothyroidism in an adult female population in Puerto Rico and to determine the relationship between hypothyroidism, bone mineral density and vertebral and non-vertebral fractures in this population. METHODS:Data from the 400 subjects' database of the Latin American Vertebral ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2013-06-01 00:00:00
abstract::The therapy of chronic myeloid leukemia (CML), characterized by the presence of the Philadelphia chromosome in the clonal hematopoietic stem cells, has changed dramatically in the last year with the development of a specific inhibitor of the BCR-ABL tyrosine kinase. This medication, STI571 or imatinib, was recently ap...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:This study aimed to assess the demographic, behavioral, and clinical factors associated with HIV and syphilis infection among a sample of men attending a sexually transmitted infection clinic during 2009 to 2010 in San Juan, Puerto Rico (PR). METHODS:A sample of 350 clinical records from men visiting the cli...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2013-03-01 00:00:00
abstract::Candida is the fourth most common cause of nosocomial bloodstream infections (BSI), being Candida albicans the most common species. This study evaluated the distribution of Candida spp isolates at a tertiary care medical center. The associated factors and outcome of patients with candidemia at the Puerto Rico Medical ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:Peripartum cardiomyopathy is a rare type of heart failure to which only pregnant women are susceptible. In Puerto Rico there is a paucity of information regarding this condition. In this report we describe our experience with peripartum cardiomyopathy. METHODS:This was a descriptive retrospective study. We c...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:Due to advances in the care of people living with HIV/AIDS (PLWHA), life expectancy significantly increased, putting this group vulnerable to age-related comorbidities, such as cancer. The objective of this study was to describe the knowledge of cancer screening (cervical, breast, anal, colon, prostate) and o...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To determine the frequency of pediatric brain tumors treated at the University Pediatric Hospital of Puerto Rico over a 6-year period and examine the demographic data and tumor histology of patients in different age groups. METHODS:A retrospective study was undertaken at the University Pediatric Hospital. We...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::The type of glass used to fabricate patch pipettes influences the kinetic properties of single-channel currents activated by acetylcholine in Xenopus myocytes. In patches formed with hard glass pipettes, the opening rate decreased in a time-dependent manner. Such decrease was most pronounced for the low conductance ch...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract::Thymidine kinase is a key enzyme responsible for the activation of several anticancer and antiviral drugs. As the first enzyme in the salvage pathway of thymidine, it is regulated by the feedback inhibition exerted by the end-product of the pathway, namely thymidine 5'-triphosphate. 5'-Aminothymidine is a non-toxic an...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:1994-03-01 00:00:00
abstract::Breastfeeding has experienced a surge in Puerto Rico thanks to the efforts of many women, as well as governmental, non-governmental and private organizations. Among the aspects which can affect the initiation, establishment and maintenance of successful breastfeeding one finds potential ethical conflicts among health ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::Hypokalemic periodic paralysis (hypoKPP) is a clinical entity characterized by recurrent skeletal muscle paralysis due to a decrease in serum potassium levels; hypoKPP can have either a primary (familial) or a secondary cause. One of the secondary causes of hypoKPP is distal renal tubular acidosis (dRTA). Distal renal...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2017-12-01 00:00:00
abstract::The development of new drugs for the pharmacological treatment of diseases is a costly and time-consuming process. The pharmaceutical industry has traditionally played the main role in the discovery, development, manufacturing and marketing of new drugs. However, in recent years, the role of academia in the process of...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract::In studying the process of protein synthesis of a silk-producing organism we have found that several macromolecules must be synthesized in order for the process to occur. Through time course studies, we have found that small RNAs may play a paramount role in directing the finely orchestrated process. Alanine tRNA, U1 ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00
abstract:BACKGROUND:Plant materials represent promising sources of anti-cancer agents. We developed and tested a novel extract from the ubiquitous plant Convolvulus arvensis. MATERIALS AND METHODS:Convolvulus arvensis components were extracted in boiling water, and small molecules were removed by high-pressure filtration. The ...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract::Aspiration of foreign bodies is more common in children than adults. The clinical and radiological findings between these two age groups are different. It is a clinical diagnosis often overlooked in adults. We hereby present an elderly male patient who was referred to us due to a one year history of hemoptysis. He was...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract::Genital human papillomavirus (HPV) infection is one of the most commonly diagnosed sexually transmitted infections world-wide. Over the last two decades, research has established a strong causal link between specific types of HPV infection and cancer, particularly cervical, anal, vulvar/vaginal, penile, and oropharyng...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章,评审
doi:
更新日期:2010-09-01 00:00:00
abstract::113 rhesus monkeys, representing 4 age classes, 3 matrilines, and immigrant adult males in a 161-member Cayo Santiago-derived troop living in a 2-acre enclosure, were sampled for levels of plasma ACTH and cortisol during a period of capture and brief cage confinement for routine veterinary examination. ACTH levels sho...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract:OBJECTIVE:To evaluate and compare the efficacy in obtaining an adequate endocervical sampling using the endocervical brush and the endocervical curettage. METHODS:Analysis of the cytology and histology of samples obtained from patients referred to the University of Puerto Rico School of Medicine Tertiary Care Center A...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the utility of the substituted judgement standard in terminally ill patients by determining agreement between patients, family proxies and physicians. BACKGROUND:Several studies have addressed the utility of substituted judgement, showing conflicting data whether surrogates are accurate predictin...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:A cross-sectional study was conducted (2012-2013) to evaluate the prevalence of 1) malocclusion and 2) occlusal characteristics in 13- to 18-yearold adolescents in San Juan, Puerto Rico (PR) from selected high schools in the municipality of San Juan. METHODS:The study sample consisted of 155 adolescents. The...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To describe the respiratory pathogens found in the bronchoalveolar lavage of a Puerto Rican population infected with the human immunodeficiency virus (HIV). BACKGROUND:Empirical treatment is an accepted strategy for management of HIV-related pneumonia, but it is usually recommended for countries that have kn...
journal_title:Puerto Rico health sciences journal
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00