Changes in the lymphoreticular system of Swiss mice subjected to antigenic stimulation, immunosuppression, or both.

Abstract:

:The influence of chronic antigenic stimulation, immunosuppression with azathioprine, or both acting simultaneously on the lymphoreticular system in Swiss mice was studied. The response consisted of abnormal hyperplasia of the lymphoreticular system with the character of malignant lymphoma. On the basis of the microscopic pattern of the changes, three types were distinguished. Chronic immunization by humoral-cellular dysregulation, can cause abnormal hyperplasia of the lymphatic system.

authors

Maniszewska B

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

227-33

issue

2

eissn

0004-069X

issn

1661-4917

journal_volume

25

pub_type

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