Psoriasis and pregnancy: hormone and immune system interaction.


BACKGROUND:Various hormonal states are known to be associated with the waxing and waning of psoriasis. Patients with psoriasis commonly experience changes in their cutaneous disease during pregnancy or post partum. OBJECTIVE:We evaluated 100 women with psoriasis by questionnaire and interview. The women had been seen at the Baylor Psoriasis Center, Dallas, and had experienced a pregnancy while having psoriasis. The answers were sorted and tabulated. In addition, we reviewed the literature to ascertain possible causes of clinical changes in psoriasis during pregnancy. RESULTS:Ninety questionnaires were completed. Sixty-nine women (76.7%) described a change in their psoriasis during pregnancy with 57 (63.3%) noting improvement. Seventy-nine patients (87.7%) had a postpartum flare, most within 4 months of delivery. CONCLUSIONS:The majority of women with psoriasis, who become pregnant, experience a change, usually an improvement, in their cutaneous disease. Pregnancy is associated with hormonal changes in estrogens and progesterone resulting in a state of altered immune surveillance.


Int J Dermatol


Boyd AS,Morris LF,Phillips CM,Menter MA




Has Abstract


1996-03-01 00:00:00












  • Contact dermatitis due to budesonide: report of five cases and review of the Japanese literature.

    abstract:BACKGROUND:Contact allergy to corticosteroids has recently gained increased attention. METHODS:Five cases of contact dermatitis due to budesonide, a nonhalogenated steroid, are described. The Japanese literature was reviewed for reports on this allergy, and the occurrence due to budesonide was compared with that of ot...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Okano M

    更新日期:1994-10-01 00:00:00

  • Senile erythroderma with serum hyper IgE.

    abstract::Eight patients with senile erythroderma with serum hyper IgE were studied. Characteristic laboratory findings were persistently elevated IgE levels, high peripheral-blood eosinophils, and high lactic dehydrogenase (LDH). Immunologic analysis using immunoglobulin antibodies showed frozen sections of inguinal lymph node...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Asai T,Horiuchi Y

    更新日期:1989-05-01 00:00:00

  • Adapalene vs. metronidazole gel for the treatment of rosacea.

    abstract:BACKGROUND:Rosacea is a common, chronic dermatosis that requires long-term therapy. Oral isotretinoin and topical and/or oral antibiotics are effective, but their usage may be limited due to side-effects. OBJECTIVE:The goal of the study was to compare the efficacy of topical adapalene gel (0.1%) and topical metronidaz...

    journal_title:International journal of dermatology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Altinyazar HC,Koca R,Tekin NS,Eştürk E

    更新日期:2005-03-01 00:00:00

  • Superficial thrombophlebitic tuberculide.

    abstract:BACKGROUND:Tuberculides are the result of immunologic reactions to hematogenously spread antigenic components of Mycobacterium tuberculosis. There are three recognized tuberculides--papulonecrotic tuberculide, erythema induratum of Bazin, and lichen scrofulosorum. In 1997, in Japan, Hara and coworkers reported five pat...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Motswaledi HM,Schulz EJ

    更新日期:2006-11-01 00:00:00

  • Are tattoos associated with negative health-related outcomes and risky behaviors?

    abstract:BACKGROUND:Tattoos have reached broadening mainstream acceptance. Medical professional societies have noted that tattoos may co-occur with high risk behaviors. METHODS:Using a variety of statistical models applied to a sample of 2,008 adults residing in the United States via Amazon's Mechanical Turk, we estimate the a...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Mortensen K,French MT,Timming AR

    更新日期:2019-07-01 00:00:00

  • Oral photochemotherapy in vitiligo: follow-up, patient compliance.

    abstract:BACKGROUND:Vitiligo is a common, acquired condition of unknown etiology. The only practical treatment for patients with vitiligo is psoralen ultraviolet A (PUVA). No satisfactory method is available to measure the influence of certain factors on the therapeutic response. METHODS:Twenty-nine patients with generalized v...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: al-Aboosi MM,Ajam ZA

    更新日期:1995-03-01 00:00:00

  • Dermatologic infestations.

    abstract::Head lice are transmitted by head to head contact. Optimal therapy includes malathion lotion 0.5% repeated in one week left on for 30 minutes to 8 hours. Spinosad topical suspension 0.9% repeated in one week left on for 10 minutes is another option. Scabies is transmitted mainly by direct contact but also via heavily ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Shmidt E,Levitt J

    更新日期:2012-02-01 00:00:00

  • Epidemiological studies on head lice infestation in Israel. I. Parasitological examination of children.

    abstract::Of 3,079 children in a medium-sized community near Jerusalem, 11.2% were found to be infested with living lice and eggs and another 23.4% had only nits. Boys and girls were equally infested. The incidence of infestation was highest among children 4-11 years of age. About 78% of the infested children had from one to te...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Mumcuoglu KY,Miller J,Gofin R,Adler B,Ben-Ishai F,Almog R,Kafka D,Klaus S

    更新日期:1990-09-01 00:00:00

  • The risk of malignancy or progression of existing malignancy in patients with psoriasis treated with biologics: case report and review of the literature.

    abstract::There is some debate regarding the risk of developing malignancy and progression of malignancy in patients with psoriasis treated with biologics. The lack of extensive, long-term, and large studies, including patients with psoriasis, to assess these aforementioned risks makes it difficult to ascertain the safety profi...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Patel S,Patel T,Kerdel FA

    更新日期:2016-05-01 00:00:00

  • A clinical and histological comparison between acute cutaneous graft-versus-host disease and other maculopapular eruptions following hematopoietic stem cell transplantation: a retrospective cohort.

    abstract:BACKGROUND:Prompt management of acute graft-versus-host disease (GVHD) may prevent its morbidity and mortality. Maculopapular (MP) eruption is a presenting sign of acute GVHD, but differentiation from other causes of MP rash is challenging. METHODS:A retrospective study was conducted among patients developing MP erupt...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Chanprapaph K,Leerunyakul K,Niparuck P,Rutnin S

    更新日期:2021-01-01 00:00:00

  • Neuropathic ulcers: a focused review.

    abstract::Neuropathic ulcers or diabetic foot ulcers are preventable ulcers associated with diabetes mellitus. These ulcers occur in the setting of unrecognized trauma, peripheral neuropathy, and foot deformities; however, they are often complicated by peripheral arterial disease and infection. Approximately 15% of individuals ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Urso B,Ghias M,John A,Khachemoune A

    更新日期:2020-12-17 00:00:00

  • The epidemiology of scabies in Turkey.

    abstract::The epidemiology of scabies for the last twelve years has been studied in Turkey. Information was obtained from three regions (Istanbul, Ankara and Erzurum) having different climates. There has been an increase in scabies in the years following 1969 in Ankara and Erzurum and from 1967 on in Istanbul. It reached its ma...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Tüzün Y,Kotoğyan A,Cenesizoğlu E,Baransü O,Ozarmağan G,Ural A,Cilara A,Gürler A,Tat AL

    更新日期:1980-01-01 00:00:00

  • Huntingtin interacting protein 1 as a histopathologic adjunct in the diagnosis of Merkel cell carcinoma.

    abstract:BACKGROUND:Huntington interacting protein 1 (HIP1), an antiapoptotic protein normally expressed in the brain, is highly expressed in Merkel cell carcinomas (MCCs). Given this, the aim of the current study was to ascertain the value of HIP1 as a histopathologic adjunct in the diagnosis of MCC. METHODS:In this retrospec...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Marghalani S,Feller JK,Mahalingam M,Mirzabeigi M

    更新日期:2015-06-01 00:00:00

  • Immunochemotherapy for cutaneous leishmaniasis: a controlled trial using killed Leishmania (Leishmania) amazonensis vaccine plus antimonial.

    abstract:BACKGROUND:Leishmaniasis is endemic in 88 countries in the world, and 350 million individuals are at risk of acquiring the disease. Treatment for American cutaneous leishmaniasis (ACL) is long, expensive, and associated with important side-effects. METHODS:In this double-blind, placebo-controlled study, we treated 102...

    journal_title:International journal of dermatology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Machado-Pinto J,Pinto J,da Costa CA,Genaro O,Marques MJ,Modabber F,Mayrink W

    更新日期:2002-02-01 00:00:00

  • Role of vascular endothelial growth factor in keloids: a clinicopathologic study.

    abstract:BACKGROUND:Despite their benign nature, keloids are usually associated with considerable cosmetic effects and may lead to functional problems. Recently, it has been reported that vascular endothelial growth factor (VEGF), a potent angiogenic factor, is overexpressed in keloid tissue and may have a potential role in its...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Salem A,Assaf M,Helmy A,Nofal A,Ibrahim S,Eldeeb F,Youssef C

    更新日期:2009-10-01 00:00:00

  • Tinea capitis in a dermatology center in the city of Fortaleza, Brazil: the role of Trichophyton tonsurans.

    abstract:BACKGROUND:Over a 3-year period (March 1999 to March 2002), 944 patients with scalp lesions attended a dermatology reference center in the city of Fortaleza, Ceará, Brazil. Clinical specimens were examined at the Specialized Medical Mycology Center, Federal University of Ceará, Fortaleza-CE, Brazil, to detect patients ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Brilhante RS,Cordeiro RA,Rocha MF,Monteiro AJ,Meireles TE,Sidrim JJ

    更新日期:2004-08-01 00:00:00

  • Cytodiagnosis of cutaneous basal and squamous cell carcinoma.

    abstract:OBJECTIVE:We performed a prospective study to evaluate the diagnostic accuracy of cytologic examination in basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs), in order to assess its clinical value. Study design Samples were taken by the "scraping" technique which involves scraping with a scalpel blade dir...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Vega-Memije E,De Larios NM,Waxtein LM,Dominguez-Soto L

    更新日期:2000-02-01 00:00:00

  • Topical zinc therapy for acne vulgaris.

    abstract::A double-blind study of 30 patients with mild to moderate acne vulgaris was conducted to evaluate the efficacy of a topically applied 2% zinc sulfate solution for acne therapy. Over a 12-week period, no difference was noted between placebo- and zinc-treated participants in regard to either the number or type of acne l...

    journal_title:International journal of dermatology

    pub_type: 临床试验,杂志文章


    authors: Cochran RJ,Tucker SB,Flannigan SA

    更新日期:1985-04-01 00:00:00

  • Cutaneous angiosarcoma in a site of healed herpes zoster.

    abstract::A 57-year-old woman presented with an erythematous plaque of the left postauricular area that was diagnosed as metastatic carcinoma on clinical and histologic bases. It was revealed that herpes zoster had been diagnosed in the same dermatomal distribution 10 years previously. The lesion recurred 2 years after irradiat...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Hudson CP,Hanno R,Callen JP

    更新日期:1984-07-01 00:00:00

  • Treatment of herpes zoster and postzoster neuralgia by subcutaneous injection of triamcinolone.

    abstract::Based on a study of 400 patients (272 patients with herpes zoster and 128 with postzoster neuralgia), the subcutaneous injection of triamcinolone in saline is concluded to be a safe and effective measure for reducing pain. The acute eruption and symptoms of herpes zoster cleared in an average of less than four days. P...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Epstein E

    更新日期:1981-01-01 00:00:00

  • The application of virtual microscopy in a dermatopathology educational setting: assessment of attitudes among dermatopathologists.

    abstract:OBJECTIVES:Whole-slide imaging with virtual microscopy is increasingly used as a tool in resident education and training, board certification and maintenance of certification examinations, and diagnostic evaluation. The objective of this study was to determine attitudes toward virtual microscopy compared with tradition...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Brick KE,Comfere NI,Broeren MD,Gibson LE,Wieland CN

    更新日期:2014-02-01 00:00:00

  • Premycotic poikiloderma, mycosis fungoides and cutaneous squamous cell carcinoma. Two cases and a discussion of their relevance.

    abstract::Two patients with premycotic poikiloderma developed one squamous cell carcinoma each. A review of the literature reveals 28 reported cases of this association, but in 26 of these the patient had been exposed to carcinogens. Our patients had no history of exposure to carcinogenic agents. In both our cases, the squamous...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Colver G,Mortimer P,Dawber R

    更新日期:1986-07-01 00:00:00

  • PTCH1 gene mutations in exon 17 and loss of heterozygosity on D9S180 microsatellite in sporadic and inherited human basal cell carcinomas.

    abstract:BACKGROUND:Basal cell carcinomas (BCCs) are the most frequent human cancer that results from malignant transformation of basal cells in the epidermis. Gorlin syndrome is a rare inherited autosomal dominant disease that predisposes with multiple BCCs and other birth defects. Both sporadic and inherited BCCs are associat...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Santos DC,Zaphiropoulos PG,Neto CF,Pimentel ER,Sanches JA Jr,Ruiz IR

    更新日期:2011-07-01 00:00:00

  • Helicobacter pylori and idiopathic chronic urticaria.

    abstract:BACKGROUND:Different studies have shown a high prevalence of Helicobacter pylori (HP) infection in patients with chronic urticaria (CU), and occasional remission of the skin lesions after eradication therapy. Recent investigations, however, have failed to find a significant relationship between the two conditions. We d...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Daudén E,Jiménez-Alonso I,García-Díez A

    更新日期:2000-06-01 00:00:00

  • Pseudopelade: an inherited alopecia.

    abstract:BACKGROUND:Pseudopelade is a rare idiopathic progressive alopecia that has no initial inflammatory phase. Even so, pseudopelade has been classified as scarring alopecia with postinflammatory alopecias. Atrophy rather than true scarring is the cardinal feature of pseudopelade. MATERIALS AND METHODS:A review of reported...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Sahl WJ

    更新日期:1996-10-01 00:00:00

  • Evaluating serum prolactin and serum dehydroepiandrosterone sulfate levels in patients with pemphigus.

    abstract:BACKGROUND:Altered levels of sex hormones have been observed in many autoimmune disorders, but there is no considerable data about pemphigus. The aim of this study is to compare serum total and free prolactin and dehydroepiandrosterone sulfate (DHEAS) levels between patients with pemphigus and healthy controls and to d...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Yousefi M,Mozafari N,Hosseini MS,Gholamin S,Razavi SM,Namazi MR,Younespour S

    更新日期:2016-06-01 00:00:00

  • Coincidence of cutaneous follicle center lymphoma and diffuse large B-cell lymphoma.

    abstract::Primary cutaneous follicle center lymphoma (PCFCL) is a neoplasm with differentiation of centrocytes and centroblasts presenting in the skin. At the time of initial manifestation, extracutaneous involvement is absent. PCFCL is considered as an indolent variant of primary cutaneous B-cell lymphomas since dissemination ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: van Tuyll van Serooskerken AM,Mosterd K,Veraart JC,Vermeer MH,Frank J,van Marion AM

    更新日期:2008-11-01 00:00:00

  • Cost-efficacy of biologic therapies for moderate to severe psoriasis from the perspective of the Taiwanese healthcare system.

    abstract:BACKGROUND:Biologic therapies are more effective than conventional therapies in the treatment of psoriasis, but they are also more costly. OBJECTIVES:The aim of this study was to compare the cost-efficacy of etanercept, adalimumab, and ustekinumab therapies in the treatment of moderate to severe psoriasis in a Taiwane...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,meta分析,评审


    authors: Wang SH,Chi CC,Hu S

    更新日期:2014-09-01 00:00:00

  • Clinical study of a new preparation of 8-methoxypsoralen in photochemotherapy.

    abstract:BACKGROUND:Oral 8-methoxypsoralen is the drug of choice in photochemotherapy of several dermatoses, e.g., vitiligo and psoriasis. The aim of this trial is to produce a new preparation of the drug, which is able to overcome the difficulties met with the oral use of the older preparations. METHODS:A new preparation cont...

    journal_title:International journal of dermatology

    pub_type: 临床试验,杂志文章


    authors: el-Mofty AM,el-Sawalhy H,el-Mofty M

    更新日期:1994-08-01 00:00:00

  • Pityriasis in dermatology: an updated review.

    abstract::Dermatology has a very distinctive lexicon. The term pityriasis refers to several dermatologic conditions which all feature scaling of the skin. According to the Merriam-Webster dictionary, the term pityriasis was first used in print in 1684. Although the diseases beginning with the name pityriasis are of diverse caus...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Chin LD,Parvinnejad N,Haber RM

    更新日期:2020-08-11 00:00:00