Post-kala-azar dermal leishmaniasis in Nepal.

Abstract:

BACKGROUND:Post-kala-azar dermal leishmaniasis (PKDL) manifests as a skin eruption after healing of visceral leishmaniasis (VL), either spontaneously or as a result of treatment. This study was undertaken to describe the demographic, clinical, and histopathologic features of PKDL in Nepal. METHODS:Demographic, clinical, microbiologic, and histopathologic features and response to treatment were studied in 22 patients with PKDL from April 1998 to March 2000. RESULTS:PKDL accounted for 0.13% of all new dermatologic cases. There were 13 (59.1%) males and nine (40.9%) females. A past history of kala-azar was present in all but one patient. A family history of kala-azar was noted in eight (36.4%) patients. All patients presented with multiple types of lesion, except for two in whom only macular lesions were seen. Oral lesions in the form of nodules and plaques were seen in four patients. Generalized lymphadenopathy was present in five patients. Slit skin smears revealed Leishman-Donovan bodies (LDBs) in nine (40.9%) patients. In macular lesions, there was a sparse infiltrate of plasma cells, lymphocytes, or histiocytes in the upper dermis. There was a dense chronic inflammatory infiltrate comprising plasma cells, lymphocytes, histiocytes, and epithelioid cells in the entire dermis from papules, plaques, or nodules. Giemsa staining of biopsy specimens revealed LDBs in seven (38.9%) patients only. Fine needle aspiration from epitrochlear lymph nodes in two patients demonstrated LDBs. All patients responded well to treatment with minimal side-effects. CONCLUSIONS:This study emphasizes the need to be aware of the possibility of cases of PKDL in endemic regions of leprosy, as the conditions may be difficult to distinguish clinically and histopathologically.

journal_name

Int J Dermatol

authors

Garg VK,Agrawal S,Rani S,Joshi A,Agarwalla A,Das ML,Koirala S

doi

10.1046/j.1365-4362.2001.01198.x

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

179-84

issue

3

eissn

0011-9059

issn

1365-4632

pii

ijd1198

journal_volume

40

pub_type

杂志文章
  • A histopathologic study of mechanic's hands associated with dermatomyositis: a report of five cases.

    abstract:BACKGROUND:Mechanic's hand is a defined specific skin eruption associated with dermatomyositis; there are few reports concerning its histopathology. As mechanic's hand clinically resembles hand eczema, it is important to distinguish between these two conditions. AIM:To determine the characteristic clinical and histopa...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2009.04164.x

    authors: Mii S,Kobayashi R,Nakano T,Harada H,Okada M,Matsui Y,Fujii T,Eto H

    更新日期:2009-11-01 00:00:00

  • Caspase-9 expression is increased in endothelial cells of active Behçet's disease patients.

    abstract:BACKGROUND:Behçet's disease is a multisystem disease of unknown etiology. Caspase-9 is responsible for initiating the caspase activation cascade during apoptosis. The aim of this study was to examine caspase-9 expression in both endothelial and perivascular infiltrates of patients with active Behçet's disease. METHODS...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2007.03209.x

    authors: Oztaş P,Lortlar N,Polat M,Alli N,Omeroğlu S,Basman A

    更新日期:2007-02-01 00:00:00

  • Leg ulcer in a patient associated with hydroxyurea therapy.

    abstract::Hydroxyurea is a hydroxylated derivate of urea commonly used in the treatment of various hematologic disorders. Cutaneous side-effects such as alopecia, diffuse hyperpigmentation, scaling, poikiloderma, atrophy of the skin and subcutaneous tissues or nail changes can develop after long-term treatment with hydroxyurea....

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2004.02450.x

    authors: Dissemond J,Hoeft D,Knab J,Franckson T,Kroger K,Goos M

    更新日期:2006-02-01 00:00:00

  • Molluscum contagiosum in Greek children: a case series.

    abstract:BACKGROUND:Epidemiological studies of molluscum contagiosum (MC) in children are limited. PATIENTS AND METHOD:Between 1997 and 1999, 110 children with MC (60 boys, 50 girls, mean age: 4.8 years) were studied. Treatment consisted of removal of all MC lesions in a single session by sterilized tweezers. RESULTS:In child...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2004.02074.x

    authors: Kakourou T,Zachariades A,Anastasiou T,Architectonidou E,Georgala S,Theodoridou M

    更新日期:2005-03-01 00:00:00

  • Behçet's disease and surgical intervention.

    abstract::Behçet's Disease (BD) is a systemic disorder with an unknown etiopathogenesis. The need for clinical criteria in the establishment of diagnosis is of great importance. We present the case of a 27-year-old man with BD, who had a surgical operation during the active period of his disease and experienced subsequent compl...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1992.tb02722.x

    authors: Bozkurt M,Torin G,Aksakal B,Ataoglu O

    更新日期:1992-08-01 00:00:00

  • Role of vascular endothelial growth factor in keloids: a clinicopathologic study.

    abstract:BACKGROUND:Despite their benign nature, keloids are usually associated with considerable cosmetic effects and may lead to functional problems. Recently, it has been reported that vascular endothelial growth factor (VEGF), a potent angiogenic factor, is overexpressed in keloid tissue and may have a potential role in its...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2009.04143.x

    authors: Salem A,Assaf M,Helmy A,Nofal A,Ibrahim S,Eldeeb F,Youssef C

    更新日期:2009-10-01 00:00:00

  • Clinicodermoscopic study of histoid leprosy: a case series.

    abstract:BACKGROUND:Histoid leprosy (HL) is a highly bacilliferous form of leprosy which requires early diagnosis and management. Dermoscopy is a noninvasive diagnostic method for various malignant and nonmalignant disorders. The aim of this study was to describe the dermoscopic patterns of various types of HL lesions over diff...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.14731

    authors: Acharya P,Mathur MC

    更新日期:2020-03-01 00:00:00

  • Sudden onset of Multiple nevi after administration of 6-mercaptopurine in an adult with Crohn's disease: a case report.

    abstract::The correlation between combined chemotherapy, including 6-mercaptopurine, and development of excessive number of melanocytic nevi in childhood has been previously reported and studied. As of yet, no such relation has been reported in adults. We recently observed a 27-year-old female patient who developed numerous ben...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2005.02086.x

    authors: Kakrida M,Orengo I,Markus R

    更新日期:2005-04-01 00:00:00

  • Mycetoma.

    abstract::We have reviewed the outstanding facts about mycetoma, including the history, first reports in India, the different causal agents according to their geographic distribution, mycologic characteristics, pathology, microbiology, behavior, evolution, immunology, experimental inoculations, associated bacterial complication...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-4362.1984.tb01238.x

    authors: Magana M

    更新日期:1984-05-01 00:00:00

  • Acupuncture in dermatology: an historical perspective.

    abstract::Classical acupuncture focuses primarily on treating the person, and secondarily treating the illness. The "symptoms" are regarded as "branch" expressions of a "root" (constitutional) imbalance. Different root imbalances can produce the same symptoms. Five patients with eczema, for example, may reveal five distinct roo...

    journal_title:International journal of dermatology

    pub_type: 历史文章,杂志文章

    doi:10.1111/j.1365-4632.2009.03899.x

    authors: Tan EK,Millington GW,Levell NJ

    更新日期:2009-06-01 00:00:00

  • Teaching & Learning Tips 1: Teaching perspectives - an introduction.

    abstract::Challenge: Clinical and research responsibilities often leave little or no time to plan thoughtful teaching encounters with trainees. This "Teaching & Learning Tips" series is designed to be an accessible guide for dermatologists who want to improve their teaching skills. It is comprised of 12 articles about how to en...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/ijd.13751

    authors: Rana J,Burgin S

    更新日期:2017-11-01 00:00:00

  • Bazex-Dupré-Christol syndrome: review of clinical and molecular aspects.

    abstract::Bazex-Dupré-Christol syndrome is a rare genodermatosis that manifests with the classical triad of basal cell carcinoma, follicular atrophoderma, and hypotrichosis; yet it may be accompanied by milia, ichthyosis, neurological symptoms, and visceral malignancies. Symptom onset is nonsimultaneous, and hence the diagnosis...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/ijd.14065

    authors: AlSabbagh MM,Baqi MA

    更新日期:2018-09-01 00:00:00

  • CO2 laser therapy in a case of steatocystoma multiplex with prominent nodules on the face and neck.

    abstract:BACKGROUND:Steatocystoma multiplex is an uncommon disorder which usually begins in adolescence or early adult life. The condition can be hereditary, as an autosomal dominant trait, or nonhereditary, as in this case. METHODS:A 40-year-old woman presented with a history of asymptomatic nodules that began around puberty ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-4362.2003.01309.x

    authors: Rossi R,Cappugi P,Battini M,Mavilia L,Campolmi P

    更新日期:2003-04-01 00:00:00

  • Cutaneous manifestations of Castleman disease.

    abstract:BACKGROUND:Castleman disease (CD) is a lymphoproliferative B-cell disease that is diagnosed from lymphoid hyperplasia with vascular proliferation. Symptoms may include fever, night sweats, and weight loss. Cutaneous manifestations often may go unnoticed since little has been described in the literature regarding them. ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.15043

    authors: Chavez-Alvarez S,Villarreal-Martinez A,Ocampo-Candiani J,Gomez-Flores M,Vazquez-Martinez O,Gonzalez-Saldivar G,Herz-Ruelas ME

    更新日期:2020-10-01 00:00:00

  • Brooke-Spiegler syndrome complicated by unilateral hearing loss.

    abstract::Brooke-Spiegler syndrome is an autosomal dominant tumor predisposition disorder. The disease is characterized by the occurrence of multiple skin appendage tumors, including cylindroma, trichoepithelioma, and spiradenoma. In some patients, tumors cover the entire head circumference, thereby causing disfigurement and ot...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2008.03963.x

    authors: Parren LJ,Bauer B,Hamm H,Frank J

    更新日期:2008-11-01 00:00:00

  • Seborrheic keratoses: a study comparing the standard cryosurgery with topical calcipotriene, topical tazarotene, and topical imiquimod.

    abstract:BACKGROUND:Patients with seborrheic keratoses frequently desire an effective topical therapy for seborrheic keratoses. OBJECTIVE:To compare topical calcipotriene, topical tazarotene, and topical imiquimod with standard cryosurgery in the treatment of seborrheic keratoses. METHODS:Fifteen patients with numerous seborr...

    journal_title:International journal of dermatology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1365-4632.2004.02282.x

    authors: Herron MD,Bowen AR,Krueger GG

    更新日期:2004-04-01 00:00:00

  • Is narrowband ultraviolet B monotherapy effective in the treatment of pityriasis lichenoides?

    abstract:BACKGROUND:Pityriasis lichenoides (PL) is a self-limiting papulosquamous disease that may persist for years and is associated with a high relapse rate. To date, few comparative studies have investigated the efficacy of narrowband ultraviolet B (NB-UVB) phototherapy and other therapies in the treatment of PL. OBJECTIVE...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2012.05814.x

    authors: Park JM,Jwa SW,Song M,Kim HS,Chin HW,Ko HC,Kim MB,Kim BS

    更新日期:2013-08-01 00:00:00

  • Fibrin deposits and fibrinolytic activity in Schonlein-Henoch syndrome.

    abstract::Previous reports have shown that alterations in cutaneous and plasmatic fibrinolytic activity are found in cutaneous necrotizing vasculitis (CNV). In a combined investigation with direct immunofluorescence and autohistographic evaluation of tissue fibrinolytic activity in the lesional skin of 20 subjects affected by S...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1983.tb03323.x

    authors: Bianchini G,Lotti T,Fabbri P

    更新日期:1983-03-01 00:00:00

  • Candida folliculitis in heroin addicts.

    abstract::Three heroin addicts had Candida folliculitis of the scalp, beard, and pubis associated with fever, chills, headache, and fatigue. In each case, pseudohyphae were found within a hair and yeasts around it and Candida was recovered from urine. These facts support a systemic dissemination. Since serious ocular and osteoa...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1986.tb04547.x

    authors: Leclerc G,Weber M,Contet-Audonneau N,Beurey J

    更新日期:1986-03-01 00:00:00

  • Successful treatment of a patient with recurrent furunculosis by vitamin C: improvement of clinical course and of impaired neutrophil functions.

    abstract:BACKGROUND:Neutrophils play a critical role in host defense against a variety of microbial pathogens. There is much information to suggest a role for vitamin C in the physiology of neutrophils. Thus, the effects of vitamin C treatment were studied in a patient with a history of recurrent furunculosis who showed altered...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1993.tb02780.x

    authors: Levy R,Schlaeffer F

    更新日期:1993-11-01 00:00:00

  • Pseudopelade: an inherited alopecia.

    abstract:BACKGROUND:Pseudopelade is a rare idiopathic progressive alopecia that has no initial inflammatory phase. Even so, pseudopelade has been classified as scarring alopecia with postinflammatory alopecias. Atrophy rather than true scarring is the cardinal feature of pseudopelade. MATERIALS AND METHODS:A review of reported...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1996.tb00644.x

    authors: Sahl WJ

    更新日期:1996-10-01 00:00:00

  • Association of Propionibacterium acnes with the efficacy of minocycline therapy for cutaneous sarcoidosis.

    abstract:BACKGROUND:Although tetracycline has been used to treat cutaneous sarcoidosis, the mechanism of action for this treatment remains unclear. This study evaluated the efficacy of minocycline treatment on cutaneous sarcoidosis and the relationship between its efficacy and the presence of Propionibacterium acnes in skin sar...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.14878

    authors: Inoue Y,Teraki Y

    更新日期:2020-06-01 00:00:00

  • Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study.

    abstract:BACKGROUND:Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue-derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC-CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of a...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.12650

    authors: Shin H,Ryu HH,Kwon O,Park BS,Jo SJ

    更新日期:2015-06-01 00:00:00

  • Efficacy of topical calcineurin inhibitors in vitiligo.

    abstract::Topical tacrolimus and pimecrolimus are indicated for the treatment of atopic dermatitis, but they have been studied in many off-label uses. We reviewed the English language literature to define their roles in treatment of vitiligo. Double-blind studies show that tacrolimus 0.1% ointment combined with excimer laser is...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-4632.2012.05697.x

    authors: Wong R,Lin AN

    更新日期:2013-04-01 00:00:00

  • 1 alpha,25-(OH)2D3 use on psoriasis and ichthyosis.

    abstract::The present work compared the clinical efficacy of topically applied 1 alpha,25-dihydroxyvitamin D3 (1 alpha,25-(OH)2D3) in 16 cases with psoriasis vulgaris, 5 with ichthyosis vulgaris and 8 with X-linked ichthyosis. Sixty-nine percent of the psoriatic cases responded to 1 alpha,25-(OH)2D3 therapy, whereas no ichthyot...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1991.tb05885.x

    authors: Okano M

    更新日期:1991-01-01 00:00:00

  • Adapalene vs. metronidazole gel for the treatment of rosacea.

    abstract:BACKGROUND:Rosacea is a common, chronic dermatosis that requires long-term therapy. Oral isotretinoin and topical and/or oral antibiotics are effective, but their usage may be limited due to side-effects. OBJECTIVE:The goal of the study was to compare the efficacy of topical adapalene gel (0.1%) and topical metronidaz...

    journal_title:International journal of dermatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-4632.2004.02130.x

    authors: Altinyazar HC,Koca R,Tekin NS,Eştürk E

    更新日期:2005-03-01 00:00:00

  • Pheohyphomycosis caused by Exophiala spinifera: a rare occurrence.

    abstract::A 10-year-old immunocompetent boy presented with multiple, verrucous, disseminated pheohyphomycotic lesions caused by Exophiala spinifera. The patient was not responsive to combination antifungal therapy (itraconazole, terbinafine, fluconazole) and cryotherapy. As antifungal susceptibility is known to be variable for ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-4632.2007.03430.x

    authors: Singal A,Pandhi D,Bhattacharya SN,Das S,Aggarwal S,Mishra K

    更新日期:2008-01-01 00:00:00

  • Absence of Merkel cells in lesional skin of vitiligo [corrected].

    abstract:BACKGROUND:In vitiligo, other than loss of melanocytes and melanin pigment in the lesional skin, keratinocytes are also involved. Human fetal Merkel cells are now generally considered to be derived from the epidermis. To date, no observations on Merkel cells in lesional skin of active vitiligo have been reported. METH...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1994.tb02859.x

    authors: Bose SK

    更新日期:1994-07-01 00:00:00

  • Misconceptions about laser treatment among dermatology patients.

    abstract:BACKGROUND:The use of lasers is very common in dermatology; however, many patients fear it and have various misconceptions about it. A literature search failed to show any studies on this topic. OBJECTIVE:To explore the various misconceptions of patients about lasers in dermatology. METHODS:A self-administered questi...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2011.05028.x

    authors: AlGhamdi KM,Moussa NA

    更新日期:2011-11-01 00:00:00

  • Tachyphylaxis to topical steroid measured by histamine-induced wheal suppression.

    abstract::Ten healthy volunteers were studied to find out whether tachyphylaxis occurs on repeated application of topical steroids. The Singh and Singh modification of the Reddy and Singh (1976) technique was used. Fluocinolone acetonide cream (0.1%) under occlusion was applied daily for 14 days on the flexor aspect of the fore...

    journal_title:International journal of dermatology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1365-4362.1986.tb02258.x

    authors: Singh G,Singh PK

    更新日期:1986-06-01 00:00:00