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The frequency of scarring after genital ulcers in Behçet's syndrome: a prospective study.

Abstract：

BACKGROUND:Although genital ulceration with or without scar formation is an important manifestation of Behçet's syndrome, formal data on the rate of genital scarring are lacking. OBJECTIVE:To study prospectively the frequency of genital scar formation after genital ulcers in patients with Behçet's syndrome. Methods One hundred and two patients (72 males and 30 females) with fresh genital ulcers presenting at a dedicated Behçet's syndrome outpatient clinic were followed for 6 weeks. The ulcer location, size, and frequency of scar formation were noted. All patients were treated with similar topical therapy. RESULTS:Two hundred and ten genital ulcers were followed in both sexes. The rate of scar formation was 66.2% (102/154) in male patients and 60.7% (34/56) in female patients. When genital ulcers were stratified as a function of size, large genital ulcers (> or = 1 cm in diameter) developed scars more frequently than did smaller ulcers (< 1 cm). The rate of scar formation in male patients with large genital ulcers was 89.4% (59/66) and with small ulcers was 48.9% (43/88) (P < 0.001). In females, all 19 large ulcers healed with scarring, and the same was true for 40.5% (15/37) of the small ulcers (chi(2) = 18.61, P < 0.001). CONCLUSION About two-thirds of genital ulcers in Behçet's syndrome leave scars. The rate of scar formation depends on the ulcer size.

journal_name

Int J Dermatol

journal_title

International journal of dermatology

authors

Mat MC,Goksugur N,Engin B,Yurdakul S,Yazici H

doi

10.1111/j.1365-4632.2006.02859.x

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

554-6

issue

5

eissn

0011-9059

issn

1365-4632

pii

IJD2859

journal_volume

45

pub_type

杂志文章

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