High-level secretion of a virally encoded anti-fungal toxin in transgenic tobacco plants.

Abstract:

:Ustilago maydis killer toxins are small polypeptides (7-14 kDa) which kill susceptible cells of closely related fungal species. The KP4 toxin is a single polypeptide subunit with a molecular weight of 11.1 kDa. In this work, a transgenic tobacco plant was constructed which secretes the KP4 toxin at a high level. The KP4 toxin expressed in this transgenic plant was of the same size and specificity as the authentic Ustilago KP4 toxin. The expression level was at least 500 times higher than that of the KP6 toxin expressed in plants. Transgenic crop plants producing the KP4 toxin could be rendered resistant to KP4-susceptible fungal pathogens.

journal_name

Plant Mol Biol

journal_title

Plant molecular biology

authors

Park CM,Berry JO,Bruenn JA

doi

10.1007/BF00020122

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

359-66

issue

2

eissn

0167-4412

issn

1573-5028

journal_volume

30

pub_type

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