Effects of chronic maternal ethanol exposure on hippocampal and striatal morphology in offspring.

abstract：:Over the past decade, the Firefighters' Burn Treatment Unit of the University of Alberta Hospital in Edmonton, Alberta, Canada, has treated 1399 inpatients suffering from thermal injury. Regional burn care is provided in a 10-bed intensive care unit with 18 plastic surgery reconstructive beds for a large referral regi...

journal_title：Annals of the New York Academy of Sciences

authors： Tredget EE,Shankowsky HA,Tilley WA

更新日期：1999-10-30 00:00:00

abstract：:The hypothalamic-pituitary-adrenocortical (HPA) axis is a major neuroendocrine system involved in the regulation of numerous physiological processes and in adaptation to stress. A wide range of variability can be observed in all the components of the system, and the contribution of genetic factors has been shown in th...

journal_title：Annals of the New York Academy of Sciences

authors： Mormede P,Foury A,Barat P,Corcuff JB,Terenina E,Marissal-Arvy N,Moisan MP

更新日期：2011-03-01 00:00:00

abstract：:Current evidence from genetic and epidemiological studies supports the view that Alzheimer's disease (AD) is a heterogeneous disorder. While the disease is pathologically defined by the presence of specified lesions in form of amyloid plaques and neurofibrillary tangles within the parenchyma, other features of patholo...

journal_title：Annals of the New York Academy of Sciences

authors： Cohen DL,Hedera P,Premkumar DR,Friedland RP,Kalaria RN

更新日期：1997-09-26 00:00:00

abstract：:Murine typhus is a cause of fever of intermediate duration in the south of Spain, where antibodies against Rickettsia typhi and Rickettsia felis were observed in humans. This study presents the first report from the northeast of Spain. Human serum samples were tested by serological test. R. typhi and R. felis seroprev...

journal_title：Annals of the New York Academy of Sciences

authors： Nogueras MM,Cardeñosa N,Sanfeliu I,Muñoz T,Font B,Segura F

更新日期：2006-10-01 00:00:00

abstract：:Chronic and intermittent ischemic vascular disorders represent a burgeoning clinical challenge. Previous studies have focused on the idea that therapeutic angiogenesis strategies could alleviate tissue ischemia; however, it is now appreciated that vascular disease is not simply limited to vascular wall cells but also ...

journal_title：Annals of the New York Academy of Sciences

authors： Pattillo CB,Fang K,Terracciano J,Kevil CG

更新日期：2010-10-01 00:00:00

abstract：:Tocopherols and tocotrienols (vitamin E) and ascorbic acid (vitamin C) as well as the carotenoids react with free radicals, notably peroxyl radicals, and with singlet molecular oxygen (1O2), this being the basis of their function as antioxidants. RRR-alpha-tocopherol is the major peroxyl radical scavenger in biologica...

journal_title：Annals of the New York Academy of Sciences

authors： Sies H,Stahl W,Sundquist AR

更新日期：1992-09-30 00:00:00

abstract：:The dramatic changes in overall mode of life experienced since 1989 by the people in Central and Eastern Europe (CEE) provides a good opportunity to study the aging processes and the status of the elderly. In the 1980s, CEE countries were already at an advanced stage of demographic aging of their populations. The firs...

journal_title：Annals of the New York Academy of Sciences

authors： Petrov IC

更新日期：2007-10-01 00:00:00

abstract：:Washington State's law for sexually violent predators was enacted in 1990; since then, 14 other states have passed similar laws authorizing civil commitment for dangerous sexual offenders following their prison terms. Although the law has survived constitutional challenges at both the state and in the U.S. Supreme Cou...

journal_title：Annals of the New York Academy of Sciences

authors： Lieb R

更新日期：2003-06-01 00:00:00

abstract：:The tumor suppressor p53 is a phosphoprotein barely detectable in the nucleus of normal cells. Upon cellular stress, particularly that induced by DNA damage, p53 can arrest cell cycle progression, thus allowing the DNA to be repaired; or it can lead to apoptosis. These functions are achieved, in part, by the transacti...

journal_title：Annals of the New York Academy of Sciences

authors： Soussi T

更新日期：2000-06-01 00:00:00

abstract：:Auditory imagery can represent many aspects of music, such as the starting pitches of a tune or the instrument that typically plays it. In this paper, I concentrate on more dynamic, or time-sensitive aspects of musical imagery, as demonstrated in two recently published studies. The first was a behavioral study that ex...

journal_title：Annals of the New York Academy of Sciences

authors： Halpern AR

更新日期：2012-04-01 00:00:00

abstract：:Venous thromboembolic events, such as pulmonary embolism, deep venous thrombosis, and portal vein thrombosis, have been observed in adult thalassemia patients, mainly in beta-thalassemia intermedia. The clinical findings are consistent with the observation of several alterations that indicate a state of activation of ...

journal_title：Annals of the New York Academy of Sciences

authors： Cappellini MD,Grespi E,Cassinerio E,Bignamini D,Fiorelli G

更新日期：2005-01-01 00:00:00

abstract：:An EEG profile for cannabis preparations equated for delta 9-THC activity has been defined in occasional cannabis users in New York and in long-term, high-dose hashish users in Athens. The EEG effects of enhanced alpha activity, decreased beta activity, and decreased mean frequency are dose dependent, both in intensit...

journal_title：Annals of the New York Academy of Sciences

authors： Fink M

更新日期：1976-01-01 00:00:00

abstract：:Taxonomic characterization of organisms in the genera Theileria and Babesia was originally based on observations of morphology and certain general phenotypic characteristics, which enabled many parasites to be unequivocally assigned to a particular genus. However, application of molecular genetic techniques, such as t...

journal_title：Annals of the New York Academy of Sciences

authors： Allsopp MT,Allsopp BA

更新日期：2006-10-01 00:00:00

abstract：:Nicotine has been found to improve memory performance in a variety of tests in rats, monkeys, and humans. Interactions of nicotinic systems with dopamine (DA) systems may be important for this effect. We conducted a series of studies of nicotinic agonist and antagonist interactions with DA systems using rats in a win-...

journal_title：Annals of the New York Academy of Sciences

authors： Levin ED,Rose JE

更新日期：1995-05-10 00:00:00

abstract：:In an effort to identify novel targets for the development of nonhormonal male contraceptives, genome-wide transcriptional profiling of the rat testis was performed. Specifically, enzymatically purified spermatogonia plus early spermatocyctes, pachytene spermatocytes, round spermatids, and Sertoli cells was analyzed a...

journal_title：Annals of the New York Academy of Sciences

authors： Johnston DS,Jelinsky SA,Zhi Y,Finger JN,Kopf GS,Wright WW

更新日期：2007-12-01 00:00:00

abstract：UNLABELLED:A new Biorex molecule, BRX-220, has been shown to be effective in animal models of diabetic neuro- and retinopathy. Recent in vitro studies showed that it might also have an insulin-sensitizing action. Therefore, the effect of BRX-220 on insulin sensitivity was compared with the action of pioglitazone (PGZ) ...

journal_title：Annals of the New York Academy of Sciences

authors： Seböková E,Kürthy M,Mogyorosi T,Nagy K,Demcáková E,Ukropec J,Koranyi L,Klimes I

更新日期：2002-06-01 00:00:00

abstract：:The relationship between the concentration of cell-free DNA (cfDNA) and the number of proliferating/apoptotic lymphocytes in peripheral blood of premature newborns of different gestation age and full-term newborns was determined. The experiments were performed using fluorescent spectrophotometry (with Hoechst 33342), ...

journal_title：Annals of the New York Academy of Sciences

authors： Tuaeva NO,Abramova ZI,Sofronov VV

更新日期：2008-08-01 00:00:00

abstract：:Previous studies, which included predominantly Caucasian populations, examined psychiatric and physical illness and associated suicide risk. We used a nationwide database to reassess the findings in an Asian population, and also analyzed the influence of different onset timing of psychiatric and physical illness and t...

journal_title：Annals of the New York Academy of Sciences

authors： Chang CF,Yeh MK,Chien WC,Chung CH,Li TT,Lai EC

更新日期：2020-02-01 00:00:00

abstract：:The W-curve is a numerical mapping algorithm that provides tertiary information content of long and short genomic sequences. The most popular genomic pattern recognition algorithms depend on string matching of the primary information content of short genomic sequences. Herein, we describe a way to define the fuzzy pro...

journal_title：Annals of the New York Academy of Sciences

authors： Cork DJ,Toguem A

更新日期：2002-12-01 00:00:00

abstract：:Proopiomelanocortin (POMC) and proenkephalin (PE) are synthesized at the endoplasmic reticulum and transported to the trans-Golgi network (TGN) where they are sorted and packaged into dense-core granules of the regulated secretory pathway (RSP). The mechanism of sorting POMC and PE to the RSP in neuroendocrine cells w...

journal_title：Annals of the New York Academy of Sciences

authors： Loh YP,Maldonado A,Zhang C,Tam WH,Cawley N

更新日期：2002-10-01 00:00:00

abstract：:Flavonoids and phenolic acids are widely distributed in higher plants and form part of the human diet. Recent interest in these substances has been stimulated by the potential health benefits arising from the antioxidant activity of these polyphenolic compounds. This review outlines the basic chemistry, biosynthesis, ...

journal_title：Annals of the New York Academy of Sciences

authors： Croft KD

更新日期：1998-11-20 00:00:00

abstract：:To live beyond the octogenarian years, population and molecular genetic studies of centenarian sibships indicate that genetic factors play an increasingly important role as the limit of life span is approached. These factors are likely to influence basic mechanisms of aging that in turn broadly influence susceptibilit...

journal_title：Annals of the New York Academy of Sciences

authors： Perls T

更新日期：2002-04-01 00:00:00

abstract：:The following on molecular mechanisms of Barrett's esophagus and adenocarcinoma contains commentaries on the mechanism of bile and gastric acid induced damage; the roles of BMP-4 and CDX-2 in the development of intestinal metaplasia; the transcription factors driving intestinalization in Barrett's esophagus; the contr...

journal_title：Annals of the New York Academy of Sciences

authors： Dvorak K,Goldman A,Kong J,Lynch JP,Hutchinson L,Houghton JM,Chen H,Chen X,Krishnadath KK,Westra WM

更新日期：2011-09-01 00:00:00

abstract：:A generation of research in cognitive psychology has given rise to many tasks that tap at various aspects of attention. It is now widely agreed that attention is not a single thing and that its measurement needs a strategy to study each of its various aspects. While there is no widely agreed taxonomy of attentional op...

journal_title：Annals of the New York Academy of Sciences

authors： Posner MI

更新日期：2008-01-01 00:00:00

abstract：:In this paper, we argue that the foundations of chemistry rely as much on the methods of measurement as they do on categories of chemical substance. To some degree, chemists perform the work of knowledge engineering: designing complex systems for the efficient retrieval of information. Indeed, in some cases, methods o...

journal_title：Annals of the New York Academy of Sciences

authors： Rothbart D,Kohout L

更新日期：2003-05-01 00:00:00

abstract：:In this paper we have sought to identify differences in alcohol consumption patterns and problems among young adult males from white, black, and Hispanic ethnic groups entering drug treatment programs. In overall consumption patterns we found results similar to those obtained in general population studies. However, ab...

journal_title：Annals of the New York Academy of Sciences

authors： Hubbard RL,Schlenger WE,Rachal JV,Bray RM,Craddock SG,Cavanaugh ER,Ginzburg HM

更新日期：1986-01-01 00:00:00

abstract：:It has previously been shown that stimulation of muscarinic m1 or m3 receptors can, by generating diacylglycerol (DAG) and activating protein kinase C (PKC), accelerate the breakdown of the amyloid precursor protein (APP) to form soluble, non-amyloidogenic peptides (APPs). This relationship has been demonstrated in hu...

journal_title：Annals of the New York Academy of Sciences

authors： Lee RK,Jimenez J,Cox AJ,Wurtman RJ

更新日期：1996-01-17 00:00:00

abstract：:The Caribbean Amblyomma Program has been operational for 8 years. However, owing to funding availability, some islands did not commence eradication activities until late 1997. During the past 2 years, 6 of the 9 islands (St. Kitts, St. Lucia, Anguilla, Montserrat, Barbados, and Dominica) under the program have attaine...

journal_title：Annals of the New York Academy of Sciences

authors： Pegram R,Indar L,Eddi C,George J

更新日期：2004-10-01 00:00:00

abstract：:Despite the high prevalence of adolescent smoking, few studies have examined nicotine sensitivity during this developmental period. In the present study we examined adolescent and adult rats' preference/aversion for a flavor previously paired with nicotine. Paired (nicotine + Kool-Aid) and unpaired (Kool-Aid) solution...

journal_title：Annals of the New York Academy of Sciences

authors： Wilmouth CE,Spear LP

更新日期：2004-06-01 00:00:00

abstract：:The adrenal glands are a major source of steroid hormone biosynthesis. In normal physiology, the pituitary hormone corticotropin (ACTH) regulates the secretion of glucocorticoids via its G protein-coupled receptor (ACTHR), the product of the MC2R gene. Aldosterone is another major product of the adrenal gland; its reg...

journal_title：Annals of the New York Academy of Sciences

authors： Bourdeau I,Stratakis CA

更新日期：2002-06-01 00:00:00