Abstract:
:We report a randomized, double-blind, parallel group, placebo-controlled study to test the effects of the acetylcholinesterase inhibitor, donepezil (5 mg/d for 30 days), on aircraft pilot performance in 18 licensed pilots with mean age of 52 years. After 30 days of treatment, the donepezil group showed greater ability to retain the capacity to perform a set of complex simulator tasks than the placebo group, p < 0.05. Donepezil appears to have beneficial effects on retention of training on complex aviation tasks in nondemented older adults.
journal_name
Neurologyjournal_title
Neurologyauthors
Yesavage JA,Mumenthaler MS,Taylor JL,Friedman L,O'Hara R,Sheikh J,Tinklenberg J,Whitehouse PJdoi
10.1212/wnl.59.1.123subject
Has Abstractpub_date
2002-07-09 00:00:00pages
123-5issue
1eissn
0028-3878issn
1526-632Xjournal_volume
59pub_type
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