Molecular immunogenetics in susceptibility to bovine dermatophilosis: a candidate gene approach and a concrete field application.

abstract：:The objective of this study was to visualize androgen receptors (ARs) in the testis, epididymis, and prostate of the stallion by means of immunohistochemistry. Nuclear immunostaining was found in all somatic cells in the testis--Leydig, Sertoli, and peritubular myoid cells; in both types of epithelial cells of the epi...

journal_title：Annals of the New York Academy of Sciences

authors： Bilinska B,Hejmej A,Gancarczyk M,Sadowska J

更新日期：2005-04-01 00:00:00

abstract：:The molecular archaeology of the mutation spectra of tumor suppressor genes generates hypotheses concerning the etiology and molecular pathogenesis of human cancer. The spectrum of somatic mutations in the p53 gene implicates environmental carcinogens and both endogenous agents and processes in the etiology of human c...

journal_title：Annals of the New York Academy of Sciences

authors： Hussain SP,Hollstein MH,Harris CC

更新日期：2000-01-01 00:00:00

abstract：:Here we describe the AddNeuroMed multicenter magnetic resonance imaging (MRI) study for longitudinal assessment in Alzheimer's disease (AD). The study is similar to a faux clinical trial and has been established to assess longitudinal MRI changes in AD, mild cognitive impairment (MCI), and healthy control subjects usi...

journal_title：Annals of the New York Academy of Sciences

authors： Simmons A,Westman E,Muehlboeck S,Mecocci P,Vellas B,Tsolaki M,Kłoszewska I,Wahlund LO,Soininen H,Lovestone S,Evans A,Spenger C,AddNeuroMed Consortium.

更新日期：2009-10-01 00:00:00

abstract：:The human ABO(H) blood group phenotypes arise from the evolutionarily oldest genetic system found in primate populations. While the blood group antigen A is considered the ancestral primordial structure, under the selective pressure of life-threatening diseases blood group O(H) came to dominate as the most frequently ...

journal_title：Annals of the New York Academy of Sciences

authors： Arend P

更新日期：2018-08-01 00:00:00

abstract：:Hantaviruses belong to the Bunyaviridae family. While usually hosted by wild mammals, they are potentially pathogenic for humans, and several serologically distinct groups associated with different syndromes have been identified. Yet, investigations have mostly been conducted where human infections by hantaviruses con...

journal_title：Annals of the New York Academy of Sciences

authors： Henttonen H,Buchy P,Suputtamongkol Y,Jittapalapong S,Herbreteau V,Laakkonen J,Chaval Y,Galan M,Dobigny G,Charbonnel N,Michaux J,Cosson JF,Morand S,Hugot JP

更新日期：2008-12-01 00:00:00

abstract：:Developmental dyslexia is associated with problems in a range of linguistic and non-linguistic skills. Some of those problems have been attributed to dysfunction of the cerebellum and its associated neural systems. Two studies of cerebellar structure were undertaken by our group. In Study 1, white and grey matter volu...

journal_title：Annals of the New York Academy of Sciences

authors： Laycock SK,Wilkinson ID,Wallis LI,Darwent G,Wonders SH,Fawcett AJ,Griffiths PD,Nicolson RI

更新日期：2008-12-01 00:00:00

abstract：:To gain better insight into mass transfer problems in encapsulated cell systems requires a combination of experimental investigations and mathematical modeling. Specific mass transfer studies are reviewed including oxygen transfer in immobilized animal cell culture bioreactors, modeling of polymer droplet formation an...

journal_title：Annals of the New York Academy of Sciences

authors： Goosen MF

更新日期：1999-06-18 00:00:00

abstract：:In vitro clonal analyses were performed to gain insight into the mechanisms that control development of neural crest-derived cardiac outflow tract mesenchyme of quail embryos. The cardiac neural crest originates from the posterior rhombencephalic neural tube. The cells leave the neural tube and migrate through the pos...

journal_title：Annals of the New York Academy of Sciences

authors： Sieber-Blum M,Ito K

更新日期：1995-03-27 00:00:00

abstract：:The lobster stomatogastric ganglion contains 30 neurons and when modulated can produce two distinct rhythmic motor patterns--the gastric mill and the pyloric. The complete neural circuitry underlying both patterns is well known. Without modulatory input no patterns are produced, and the neurons fire tonically or are s...

journal_title：Annals of the New York Academy of Sciences

authors： Selverston A,Elson R,Rabinovich M,Huerta R,Abarbanel H

更新日期：1998-11-16 00:00:00

abstract：:Stationary-phase mutation (a subset of which was previously called adaptive mutation) occurs in apparently nondividing, stationary-phase cells exposed to a nonlethal genetic selection. In one experimental system, stationary-phase reversion of an Escherichia coli F'-borne lac frameshift mutation occurs by a novel molec...

journal_title：Annals of the New York Academy of Sciences

authors： Lombardo MJ,Torkelson J,Bull HJ,McKenzie GJ,Rosenberg SM

更新日期：1999-05-18 00:00:00

abstract：:Cross-species hybridizations have enabled us to isolate and clone the gene for the beta chain of human fibrinogen. Highlights of the gene for the beta chain revealed by nucleotide sequence analyses, particularly in areas that have a direct bearing on defining the overall organization of the gene, have been presented. ...

journal_title：Annals of the New York Academy of Sciences

authors： Chung DW,Rixon MW,Que BG,Davie EW

更新日期：1983-06-27 00:00:00

abstract：:Alzheimer's disease (AD) impairs olfaction, but it is uncertain how early this occurs in the disease process and whether the effect can be accounted for by other behavioral or genetic markers of the disease. We administered the Brief Smell Identification Test (BSIT) to 471 older people without dementia or cognitive im...

journal_title：Annals of the New York Academy of Sciences

authors： Wilson RS,Arnold SE,Schneider JA,Boyle PA,Buchman AS,Bennett DA

更新日期：2009-07-01 00:00:00

abstract：:Hematopoietic stem cells (HSCs) have been long proposed to reside in defined anatomical locations within bone marrow (BM) tissues in direct contact or close proximity to nurturing cell types. Imaging techniques that allow the simultaneous mapping of HSCs and interacting cell types have been central to the discovery of...

journal_title：Annals of the New York Academy of Sciences

authors： Gomariz A,Isringhausen S,Helbling PM,Nombela-Arrieta C

更新日期：2020-04-01 00:00:00

abstract：:Intentional exposures to toxic chemicals can stem from terrorist attacks, such as the release of sarin in the Tokyo subway system in 1995, as well as from toxic industrial accidents that are much more common. Developing effective medical interventions is a critical component of the overall strategy to overcome the cha...

journal_title：Annals of the New York Academy of Sciences

authors： Jett DA

更新日期：2016-06-01 00:00:00

abstract：:A meta-analysis of 14 clinical studies with RRR- or all-rac-alpha-tocopherol (83,800 subjects) was performed to evaluate whether RRR and all-rac differ in cardiovascular efficacy based on those clinical endpoints that are most consistently documented in the publications of the studies. Odds ratios of treatment versus ...

journal_title：Annals of the New York Academy of Sciences

authors： Kraemer K,Koch W,Hoppe PP

更新日期：2004-12-01 00:00:00

abstract：:Since the early 1980s biologists have recognized that skeletal muscle generates free radicals. Of particular interest are two closely related redox cascades--reactive oxygen species (ROS) and nitric oxide (NO) derivatives. The ROS cascade is initiated by superoxide anion radicals derived from the mitochondrial electro...

journal_title：Annals of the New York Academy of Sciences

authors： Reid MB,Durham WJ

更新日期：2002-04-01 00:00:00

abstract：:The National Institutes of Health's Clinical and Translational Science Award (CTSA) program has had a profound impact on clinical research and training methods at the University of California, Davis (UC Davis). UC Davis was among the first 12 institutions to receive NIH funding for this award, and created its Clinical...

journal_title：Annals of the New York Academy of Sciences

authors： Kasim-Karakas S,Hyson D,Halsted C,van Loan M,Chedin E,Berglund L

更新日期：2010-03-01 00:00:00

abstract：:Gonad-stimulating substance (GSS) is the first invertebrate gonadotropic neuropeptide hormone identified in a marine invertebrate, the starfish. Here, we show expression and distribution of GSS in various organs of the starfish Asterina pectinifera. Levels of GSS were high in the radial nerves and nerve ring. GSS was ...

journal_title：Annals of the New York Academy of Sciences

authors： Mita M,Ito C,Kubota E,Nagahama Y,Shibata Y

更新日期：2009-04-01 00:00:00

abstract：:The mesodiencephalic junction is the site of the prenuclear control of vertical eye motion. We measured vertical saccades, smooth pursuit (SP), the vertical vestibulo-ocular reflex (VOR), and its interactions with vision during active head motion in 21 patients with midbrain lesions causing palsy of vertical saccades,...

journal_title：Annals of the New York Academy of Sciences

authors： Sharpe JA,Kim JS

更新日期：2002-04-01 00:00:00

abstract：:The present experiments were conducted to determine the effects of neurotensin on secretion of a variety of anterior pituitary hormones. Conscious rats with indwelling cannulae in the third ventricle and external jugular vein were used and the effects on plasma hormone levels measured by radioimmunoassay. Neurotensin ...

journal_title：Annals of the New York Academy of Sciences

authors： McCann SM,Vijayan E,Koenig J,Krulich L

更新日期：1982-01-01 00:00:00

abstract：:The endocannabinoid system, through the cannabinoid receptor CB1, is involved in the modulation of adaptive responses to environmental conditions. However, little is known about the role of the cannabinergic system, particularly CB1 receptor expression, in relation to the effects induced by xenoestrogens concerning th...

journal_title：Annals of the New York Academy of Sciences

authors： Palermo FA,Angelini M,Cottone E,Virgili M,Franzoni MF,Mosconi G,Polzonetti-Magni AM

更新日期：2009-04-01 00:00:00

abstract：:Tick burdens cause direct damage to hosts and transmit several disease agents, the majority of which are secreted into feeding lesions through tick salivary glands. Reduced incidence of naturally transmitted tick-borne diseases was recently observed among cattle immunized with tick salivary gland extracts (TSGE). The ...

journal_title：Annals of the New York Academy of Sciences

authors： Jittapalapong S,Phichitrasilp T,Chanphao H,Rerkamnuychoke W,Stich RW

更新日期：2008-12-01 00:00:00

abstract：:Cholinesterase inhibitors used to treat Alzheimer's disease according to the principle of cholinergic replacement therapy have proved to be less beneficial than expected. The present study was designed to investigate the cerebrovascular response to physostigmine and tacrine in the experimental model of lesioning of th...

journal_title：Annals of the New York Academy of Sciences

authors： Peruzzi P,von Euw D,Lacombe P

更新日期：2000-04-01 00:00:00

abstract：:Sm-p80-based vaccine efficacy for Schistosoma mansoni was evaluated in a baboon model of infection and disease. The study was designed to replicate a human vaccine implementation scenario for endemic regions in which vaccine would be administered following drug treatment of infected individuals. In our study, the Sm-p...

journal_title：Annals of the New York Academy of Sciences

authors： Siddiqui AJ,Molehin AJ,Zhang W,Ganapathy PK,Kim E,Rojo JU,Redman WK,Sennoune SR,Sudduth J,Freeborn J,Hunter D,Kottapalli KR,Kottapalli P,Wettashinghe R,van Dam GJ,Corstjens PLAM,Papin JF,Carey D,Torben W,Ahmad G,S

更新日期：2018-08-01 00:00:00

abstract：:Sophisticated imaging and fetal sampling techniques have defined the natural history and pathophysiologic characteristics of many previously mysterious conditions of newborn. Although most prenatally diagnosed malformations are best managed by appropriate medical and surgical therapy after delivery, an increasing numb...

journal_title：Annals of the New York Academy of Sciences

authors： Albanese CT,Harrison MR

更新日期：1998-06-18 00:00:00

abstract：:The superior soft tissue contrast and multiplanar capability of magnetic resonance imaging has contributed to earlier diagnosis and implementation of effective treatment for a variety of arthropathies. Owing to overlapping clinical signs and symptoms, MRI plays a role in delineating the features and stages of these co...

journal_title：Annals of the New York Academy of Sciences

authors： Momeni M,Brindle K

更新日期：2009-02-01 00:00:00

abstract：:The amygdala and orbitofrontal cortex (OFC) are often thought of as components of a neural circuit that assigns affective significance--or value--to sensory stimuli so as to anticipate future events and adjust behavioral and physiological responses. Much recent work has been aimed at understanding the distinct contrib...

journal_title：Annals of the New York Academy of Sciences

authors： Salzman CD,Paton JJ,Belova MA,Morrison SE

更新日期：2007-12-01 00:00:00

abstract：:The Sex combs reduced gene of the Antennapedia complex specifics the identities of the anterior thoracic and posterior head segments, including the primordium of the larval salivary gland. The Sex combs reduced transcription unit spans over 30 kb of genomic DNA, with another 40 kb of upstream cis-regulatory sequences....

journal_title：Annals of the New York Academy of Sciences

authors： Kennison JA,Vázquez M,Brizuela BJ

更新日期：1998-04-15 00:00:00

abstract：:Internuclear ophthalmoparesis (INO) is the most common saccadic eye movement disorder observed in patients with multiple sclerosis (MS). It is characterized by slowing of the adducting eye during horizontal saccades, and most commonly results from a demyelinating lesion in the medial longitudinal fasciculus (MLF) with...

journal_title：Annals of the New York Academy of Sciences

authors： Frohman TC,Davis SL,Frohman EM

更新日期：2011-09-01 00:00:00

abstract：:Our studies of Ca2+ release have shown that three classes of compounds--quercetin, which inhibits Ca2+ release by reversal of the Ca2+ pump, H+ ionophores and DCCD, which affect proton gradients, and lipophilic anions, which act to oppose a separation of membrane surface charges--all have potential in probing the mech...

journal_title：Annals of the New York Academy of Sciences

authors： MacLennan DH,Shoshan V,Wood DS

更新日期：1982-01-01 00:00:00