Expression and distribution of gonad-stimulating substance in various organs of the starfish Asterina pectinifera.

abstract：:Dysregulation of apoptosis is associated with the pathogenesis of organ-specific autoimmune diseases, through altered target organ susceptibility. Apoptosis signaling pathways can be initiated through activation of death receptors such as Fas. A comparative analysis of the expression of Fas and FasL, the antiapoptotic...

journal_title：Annals of the New York Academy of Sciences

authors： Salmaso C,Bagnasco M,Pesce G,Montagna P,Brizzolara R,Altrinetti V,Richiusa P,Galluzzo A,Giordano C

更新日期：2002-06-01 00:00:00

abstract：:The Br-type neuron of the snail Helix pomatia, involved in neuronal regulation of various homeostatic and adaptive mechanisms, represents an interesting model for studying effects of temperature change on neuronal activity of poikilotherms. Acetylcholine induces a transient, inward dose-dependent current in the identi...

journal_title：Annals of the New York Academy of Sciences

authors： Nedeljković M,Kartelija G,Radenović L

更新日期：2005-06-01 00:00:00

abstract：:The adaptation of the vestibulo-ocular reflex (VOR) was studied in 26 normal subjects and 26 patients with cerebellar lesions, using horizontal vision-reversal prisms. In normal subjects, the adaptation of gain after wearing prisms for one hour was approximately 50% of the VOR value in the dark. In contrast to this, p...

journal_title：Annals of the New York Academy of Sciences

authors： Yagi T,Shimizu M,Sekine S,Kamio T,Suzuki JI

更新日期：1981-01-01 00:00:00

abstract：:Neuropathologic examination in elderly individuals and patients with Parkinson's disease with and without dementia reveals abundant isocortical amyloid deposits with no or only a few neuritic plaques, neuropil threads (NT), and neurofibrillary tangles (NFT), whereas NT and NFT may be present only in the entorhinal reg...

journal_title：Annals of the New York Academy of Sciences

authors： Jellinger K,Braak H,Braak E,Fischer P

更新日期：1991-01-01 00:00:00

abstract：:Peroxisomes are capable of oxidizing a variety of substrates including (poly)unsaturated enoyl-CoA esters. The beta-oxidation of unsaturated enoyl-CoA esters in peroxisomes, and also in mitochondria, is not just chain-shortening but also involves the metabolizing of pre-existing carbon-to-carbon double bonds. In addit...

journal_title：Annals of the New York Academy of Sciences

authors： Hiltunen JK,Filppula SA,Koivuranta KT,Siivari K,Qin YM,Häyrinen HM

更新日期：1996-12-27 00:00:00

abstract：:Syndrome X is a clinical syndrome in which multiple risks cluster in an individual, and it is a common basis of vascular disease in the industrial countries. The molecular basis of Syndrome X, however, has not been elucidated. We have analyzed body fat distribution using CT scan and have shown that people who have acc...

journal_title：Annals of the New York Academy of Sciences

authors： Matsuzawa Y,Funahashi T,Nakamura T

更新日期：1999-11-18 00:00:00

abstract：:TP73, as a TP53 homologue, drew the attention of tumor biologists because it is rarely mutated in human cancers and can induce cell cycle arrest and apoptosis by activating genes also regulated by p53. However, TP73 harbors an additional promoter that produces a dominant negative p73 protein (deltaNp73) having the opp...

journal_title：Annals of the New York Academy of Sciences

authors： Rossi M,Sayan AE,Terrinoni A,Melino G,Knight RA

更新日期：2004-12-01 00:00:00

abstract：:This article reviews research on the Finnish model of peer-group mentoring (PGM). The theoretical foundation of the model is based on the constructivist theory of learning, the concept of autonomy in teaching profession, peer learning, and narrative identity work. The model has been disseminated nationwide in the educ...

journal_title：Annals of the New York Academy of Sciences

authors： Tynjälä P,Pennanen M,Markkanen I,Heikkinen HLT

更新日期：2021-01-01 00:00:00

abstract：:Two chemical classes of flavonoids, the flavan-3-ols (catechins and proanthocyanidins) and the anthocyanins, are the natural antioxidants present at the highest concentration in red grape and wine. In the berry, the anthocyanins are localized in the skins, similarly to other highly bioactive phenolics of grape such as...

journal_title：Annals of the New York Academy of Sciences

authors： Mattivi F,Zulian C,Nicolini G,Valenti L

更新日期：2002-05-01 00:00:00

abstract：:N-type calcium channels both generate the initial calcium signal to trigger neurotransmitter release and also interact with synaptic release proteins at many mammalian central nervous system synapses. Two isoforms of the alpha 1B N-type channel from rat brain (alpha 1B-I and alpha 1B-II) were found to differ in four r...

journal_title：Annals of the New York Academy of Sciences

authors： Stea A,Dubel SJ,Snutch TP

更新日期：1999-04-30 00:00:00

abstract：:To identify factors regulating neurogenesis and programmed cell death in mouse olfactory epithelium (OE), and to determine the mechanisms by which these factors act, we have studied mouse OE using two major experimental paradigms: tissue culture of embryonic OE and cell types isolated from it; and ablation of the olfa...

journal_title：Annals of the New York Academy of Sciences

authors： Calof AL,Rim PC,Askins KJ,Mumm JS,Gordon MK,Iannuzzelli P,Shou J

更新日期：1998-11-30 00:00:00

abstract：:Systemic administration of 5,7-HT to newborn rats produces an altered development of the 5-HT neurons in the central nervous system, with marked regional differences. 5,7-Hydroxytryptamine can enter the brain and elicit its neurotoxic actions after systemic administration in the neonatal stage due to an incompletely d...

journal_title：Annals of the New York Academy of Sciences

authors： Jonsson G,Pollare T,Hallman H,Sachs C

更新日期：1978-06-12 00:00:00

abstract：:Piracetam and structurally related nootropics are known to potentiate the anticonvulsant effects of antiepileptic drugs. It remains to be seen, however, whether these nootropics inhibit proconvulsant actions of many toxic agents including Ro 5-4864, a specific agonist for peripheral-type benzodiazepine receptors (PBR)...

journal_title：Annals of the New York Academy of Sciences

authors： Nakamoto Y,Shiotani T,Watabe S,Nabeshima T,Yoshii M

更新日期：2004-10-01 00:00:00

abstract：:Recent study demonstrated that M55V variant in SUMO4 at IDDM5 was associated with susceptibility to type 1 diabetes. Subsequent studies, however, showed inconsistency in the association. To clarify the population-wide effect on the association of SUMO4 with type 1 diabetes, we have performed meta-analysis including ou...

journal_title：Annals of the New York Academy of Sciences

authors： Noso S,Ikegami H,Fujisawa T,Kawabata Y,Asano K,Hiromine Y,Sugihara S,Lee I,Kawasaki E,Awata T,Ogihara T

更新日期：2006-10-01 00:00:00

abstract：:Explanations of the socioeconomic gradient in health status must account for the observations that the gradient cuts across a wide range of disease processes and is capable of replicating itself on new disease processes as they emerge in society. Understanding this pattern requires an understanding of how human organi...

journal_title：Annals of the New York Academy of Sciences

authors： Hertzman C

更新日期：1999-01-01 00:00:00

abstract：:This work examines distinct aspects of effortful control and attention predicted aggression in a group of children at elevated risk for the development of conduct problems. Results suggested that behavioral inhibition, rather than attentional control, best predicted maternal reports of child aggressive behaviors. ...

journal_title：Annals of the New York Academy of Sciences

authors： Dennis TA,Brotman LM

更新日期：2003-12-01 00:00:00

abstract：:Chronic hypoxic stimulation in mammals can induce several phenotypic changes, such as polycythemia, pulmonary vascular changes, pulmonary hypertension, and carotid body (CB) enlargement. These phenotypic alterations provide a tool to test whether an oxygen sensor candidate is involved in an organism's response to envi...

journal_title：Annals of the New York Academy of Sciences

authors： Baysal BE

更新日期：2006-08-01 00:00:00

abstract：:The dietary preferences, gastrointestinal anatomy, digestive physiology, biochemical capabilities, and commensal microflora of a bird are collectively known as its nutritional strategy. Measurement of hormones in droppings requires an appreciation of an animal's nutritional strategy in order to optimize collection pro...

journal_title：Annals of the New York Academy of Sciences

authors： Klasing KC

更新日期：2005-06-01 00:00:00

abstract：:N. gonorrhoeae initiates infection by adhering to and invading columnar epithelial cells. Over time these activities often induce inflammation, with the influx of neutrophils and serum into the urethral lumen, cervical os, conjunctiva, and the like. At least some of these infected niches contain CMP-NANA (cytidine mon...

journal_title：Annals of the New York Academy of Sciences

authors： Rest RF,Liu J,Talukdar R,Frangipane JV,Simon D

更新日期：1994-08-15 00:00:00

abstract：:Aging, hypoxia, and thiamin deficiency diminish motor performance. Similar alterations of ACh, DA, and glutamate metabolism accompany hypoxia, thiamin deficiency, and aging. Both aging and hypoxia reduce ACh release and stimulate DA and glutamate release. Presynaptic enhancement of DA and glutamate release may be impo...

journal_title：Annals of the New York Academy of Sciences

authors： Freeman GB,Gibson GE

更新日期：1988-01-01 00:00:00

abstract：:Odorant signals are detected by binding of odor molecules to odorant receptors. These belong to the G protein-coupled receptor family. They in turn couple to G proteins, most of which induce cAMP production. This second messenger activates ion channels to depolarize the olfactory sensory neuron, thus providing a signa...

journal_title：Annals of the New York Academy of Sciences

authors： Wicher D,Schäfer R,Bauernfeind R,Stensmyr MC,Heller R,Heinemann SH,Hansson BS

更新日期：2009-07-01 00:00:00

abstract：:The term sepsis describes a potentially lethal clinical condition that develops as a result of a dysregulated host response to bacterial infection. The most common bacterial component implicated in initiating the septic syndrome is a cell wall molecule derived from Gram-negative bacteria, known as lipopolysaccharide (...

journal_title：Annals of the New York Academy of Sciences

authors： Bosshart H,Heinzelmann M

更新日期：2007-01-01 00:00:00

abstract：:To understand the molecular mechanism of endometrial differentiation we have initiated an analysis of the uteroglobin promoter. Uteroglobin is normally expressed in endometrial tissues under the control of ovarian hormones. In gene transfer experiments with the Ishikawa cell line, derived from a human endometrial aden...

journal_title：Annals of the New York Academy of Sciences

authors： Helftenbein G,Misseyanni A,Hagen G,Peter W,Slater EP,Wiehle RD,Suske G,Beato M

更新日期：1991-01-01 00:00:00

abstract：:Perhaps the greatest mystery is why the universe exists in the first place. How is it possible for something to emerge from nothing, or has a universe in some form always existed? This question of origins-both of the universe as a whole and of the fundamental laws of physics-raises profound scientific, philosophical, ...

journal_title：Annals of the New York Academy of Sciences

authors： Paulson S,Albert D,Holt J,Turok N

更新日期：2015-12-01 00:00:00

abstract：:We have been interested in the consequences of foreign DNA insertion into established mammalian genomes and have initially studied this problem in adenovirus type 12 (Ad12)-transformed cells or in Ad12-induced hamster tumors. Since integrates are frequently methylated de novo, it appears that they might be modified by...

journal_title：Annals of the New York Academy of Sciences

authors： Doerfler W,Hohlweg U,Müller K,Remus R,Heller H,Hertz J

更新日期：2001-09-01 00:00:00

abstract：:While the study of nationalism has received much attention throughout the social sciences and humanities, the experimental investigation of it lags behind. In this paper we review recent advances in the examination of implicit nationalism. In the first set of experiments we survey, the Palestinian, Israeli, Italian, a...

journal_title：Annals of the New York Academy of Sciences

authors： Hassin RR,Ferguson MJ,Kardosh R,Porter SC,Carter TJ,Dudareva V

更新日期：2009-06-01 00:00:00

abstract：:The fourth component of complement (C4) occurs in human plasma as a protein with a three polypeptide chain structure. Lately a single-chain form of C4 has been purified from human plasma by sequential steps of immunoadsorbent chromatography, gel filtration in 6 M guanidine hydrochloride, and gel filtration in 6 M guan...

journal_title：Annals of the New York Academy of Sciences

authors： Gorski JP,Muller-Eberhard HJ

更新日期：1980-01-01 00:00:00

abstract：:As insulin is a major autoantigen in autoimmune diabetes and because the insulin gene region locus in humans has been linked to diabetes risk, we have bred insulin gene knockouts onto the NOD mouse. Mice differ from humans in terms that they express two nonallelic genes of insulin. Insulin 2 is the murine homologue of...

journal_title：Annals of the New York Academy of Sciences

authors： Paronen J,Moriyama H,Abiru N,Sikora K,Melanitou E,Babu S,Bao F,Liu E,Miao D,Eisenbarth GS

更新日期：2003-11-01 00:00:00

abstract：:A 1.2 kb polymorphic fragment from the Gardel isolate of Ehrlichia (formerly Cowdria) ruminantium was used to isolate a 15kb clone from the E. ruminantium Welgevonden LambdaGEM-11 library. This clone, WL2EL1, was subcloned and sequenced. Eight open reading frames (ORFs) were identified. The ORF in WL2EL1 which contain...

journal_title：Annals of the New York Academy of Sciences

authors： Louw E,Brayton KA,Collins NE,Pretorius A,Van Strijp F,Allsopp BA

更新日期：2002-10-01 00:00:00

abstract：:The perceptions of coccidioidomycosis as a medical problem has undergone sequential and dramatic metamorphoses since its first description more than a century ago. First thought to be rare and lethal, coccidioidomycosis was subsequently found to be common and often mild. During World War II, its overall impact upon la...

journal_title：Annals of the New York Academy of Sciences

authors： Galgiani JN

更新日期：2007-09-01 00:00:00