MRI measures of Alzheimer's disease and the AddNeuroMed study.

abstract：:Interleukin (IL)-17-producing helper T (Th17) cells serve as a Th subset involved in epithelial cell- and neutrophil-mediated immune responses against extracellular microbes and in the development of various autoimmune diseases. The differentiation of Th17 cells is controlled by a number of intracellular signaling cas...

journal_title：Annals of the New York Academy of Sciences

authors： Nagai S,Kurebayashi Y,Koyasu S

更新日期：2013-03-01 00:00:00

abstract：:Maize (Zea mays), also called corn, is believed to have originated in central Mexico 7000 years ago from a wild grass, and Native Americans transformed maize into a better source of food. Maize contains approximately 72% starch, 10% protein, and 4% fat, supplying an energy density of 365 Kcal/100 g and is grown throug...

journal_title：Annals of the New York Academy of Sciences

authors： Ranum P,Peña-Rosas JP,Garcia-Casal MN

更新日期：2014-04-01 00:00:00

abstract：:Our paper reviews recent progress in the study and understanding of observed trends in extreme rainfall events in the Metropolitan Area of São Paulo (MASP). These are discussed in relation to hydrometeorological hazards that trigger natural disasters, such as flash floods, landslides, and droughts, that affect the pop...

journal_title：Annals of the New York Academy of Sciences

authors： Marengo JA,Alves LM,Ambrizzi T,Young A,Barreto NJC,Ramos AM

更新日期：2020-07-01 00:00:00

abstract：:The recent literature providing insights from neuroscience and evolutionary biology into how individuals perceive risky choice situations represents a "second wave" of findings that recapitulates as well as challenges the risk perception research begun in the 1980s, which relied on psychometric survey research. Gleani...

journal_title：Annals of the New York Academy of Sciences

authors： Finkel AM

更新日期：2008-04-01 00:00:00

abstract：:Why does music pervade our lives and those of all known human beings living today and in the recent past? Why do we feel compelled to engage in musical activity, or at least simply enjoy listening to music even if we choose not to actively participate? I argue that this is because musicality--communication using varia...

journal_title：Annals of the New York Academy of Sciences

authors： Mithen S

更新日期：2009-07-01 00:00:00

abstract：:Interleukin (IL)-11 is a member of the gp130 family of cytokines. Comparison of IL-11 with another gp130 family member, IL-6, indicates that these two cytokines share many overlapping signal transduction mechanisms. However, unlike IL-6, treatment of patients with a recombinant human form of IL-11 (rhIL-11) does not i...

journal_title：Annals of the New York Academy of Sciences

authors： Trepicchio WL,Dorner AJ

更新日期：1998-09-29 00:00:00

abstract：:Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. The use of herbal drugs is once more escalating in the form of complementary and alternative medicine. The past century...

journal_title：Annals of the New York Academy of Sciences

authors： Cragg GM,Newman DJ

更新日期：2001-12-01 00:00:00

abstract：:Endometrial carcinoma is the most common cancer of the female reproductive organs in the United States. International comparisons reveal that the incidence of endometrial cancer vary widely between different countries with the highest rates observed in North America and Northern Europe, intermediate rates in Eastern E...

journal_title：Annals of the New York Academy of Sciences

authors： Akhmedkhanov A,Zeleniuch-Jacquotte A,Toniolo P

更新日期：2001-09-01 00:00:00

abstract：:Data have been presented to document that the human newborn is a conditionable organism. Babies in the first days of life possess sensitivity to stimulation in all sensory modalities, an unconditioned repertoire of responses to some of these sensory stimuli, and a capacity for associating simultaneously presented stim...

journal_title：Annals of the New York Academy of Sciences

authors： Lipsitt LP

更新日期：1990-01-01 00:00:00

abstract：:Currently, it is known that several chemical agents used or generated by the oil industry are classified as mutagens and/or carcinogens. Among these we have gasoline, diesel, butane gas, styrene, benzene, chloroform, and others. Studies have verified that these chemicals have effects in fertility (abortions, sterility...

journal_title：Annals of the New York Academy of Sciences

authors： Paz-y-Miño C,López-Cortés A,Arévalo M,Sánchez ME

更新日期：2008-10-01 00:00:00

abstract：:Normal human mitotic cells do not proliferate indefinitely in culture but undergo a limited number of divisions and progressively reach a state of irreversible growth arrest, a process termed replicative senescence. Hypoxia is a situation of reduced oxygen concentration that relates to many physiological and pathophys...

journal_title：Annals of the New York Academy of Sciences

authors： Poulios E,Trougakos IP,Chondrogianni N,Gonos ES

更新日期：2007-11-01 00:00:00

abstract：:These findings demonstrate that calcium antagonists reverse renal vasoconstriction in a variety of settings. The ability of calcium antagonists to augment GFR of the vasoconstricted kidney is striking and has also been demonstrated in a number of in vivo settings. These observations and others raise the possibility th...

journal_title：Annals of the New York Academy of Sciences

authors： Loutzenhiser R,Epstein M

更新日期：1988-01-01 00:00:00

abstract：:We have shown that drinking red wine reduces oxidation of LDL. This reduction in oxidation has been attributed to the polyphenolic compounds in red wine, but the mechanisms of absorption and metabolism of these compounds has been unclear. We therefore investigated the absorption and metabolism of polyphenols using rat...

journal_title：Annals of the New York Academy of Sciences

authors： Yamashita S,Sakane T,Harada M,Sugiura N,Koda H,Kiso Y,Sezaki H

更新日期：2002-05-01 00:00:00

abstract：:Mast cells located in connective tissues are a potent source of vasoactive and inflammatory mediators, such as cytokines. They accumulate in tissues in a wide variety of diseases where their function in most cases in unclear. In this report we provide evidence that rat basophilic leukemia cells (RBLC) cultured with a ...

journal_title：Annals of the New York Academy of Sciences

authors： Conti P,Barbacane RC,Trakatellis M,Placido FC,Cataldo I,Reale M

更新日期：1997-12-15 00:00:00

abstract：:Brown adipose tissue (BAT) is an endocrine organ that contributes to thermogenesis and energy consumption. We investigated the effects of salt loading and surgical removal of whitened interscapular BAT (iBAT) on cardiac and adipose tissue pathology in DahlS.Z-Leprfa /Leprfa (DS/obese) rats, an animal model of metaboli...

journal_title：Annals of the New York Academy of Sciences

authors： Komatsu Y,Aoyama K,Yoneda M,Ito S,Sano Y,Kawai Y,Cui X,Yamada Y,Furukawa N,Ikeda K,Nagata K

更新日期：2020-12-19 00:00:00

abstract：:The extensive literature and the work from our laboratory illustrate the large number of complex processes affected by estrogen that might contribute to the striking ability of 17-beta estradiol (E2) and its derivatives to inhibit clinical and histological signs of experimental autoimmune encephalomyelitis (EAE) in mi...

journal_title：Annals of the New York Academy of Sciences

authors： Offner H,Polanczyk M

更新日期：2006-11-01 00:00:00

abstract：:Megadose haploidentical transplants, mismatched at three HLA loci, engraft rapidly and durably without induction of graft-versus-host disease (GVHD). In vitro studies suggest that veto cells, contained in the population of hematopoietic progenitors, facilitate this favorable outcome. Cytotoxic T cells, not reactive ag...

journal_title：Annals of the New York Academy of Sciences

authors： Reisner Y

更新日期：2001-06-01 00:00:00

abstract：:The vertebrate neuromuscular junction (NMJ) is a "tripartite" synapse, composed of three cellular elements: the presynaptic nerve terminal, the postsynaptic specialization, and synapse-associated glial cells, called perisynaptic Schwann cells (PSCs; also called terminal Schwann cells). During development, PSCs grow be...

journal_title：Annals of the New York Academy of Sciences

authors： Feng Z,Ko CP

更新日期：2008-01-01 00:00:00

abstract：:Posttranscriptional control of gene expression plays a key role in regulating gene expression in cells undergoing apoptosis. Cyclooxygenase-2 (COX-2) is a crucial enzyme in the conversion of arachidonic acid to prostaglandin E2 (PGE(2)) and is significantly upregulated in many types of adenocarcinomas. COX-2 overexpre...

journal_title：Annals of the New York Academy of Sciences

authors： Mukhopadhyay D,Jung J,Murmu N,Houchen CW,Dieckgraefe BK,Anant S

更新日期：2003-12-01 00:00:00

abstract：:Apolipoprotein E is a plasma cholesterol and phospholipid transporter which plays a central role in lipoprotein metabolism in the brain. Apolipoprotein E is a polymorphic protein with three common alleles in the general population, designated epsilon 2, epsilon 3 and epsilon 4 coding for proteins ApoE2, ApoE3 and ApoE...

journal_title：Annals of the New York Academy of Sciences

authors： Beffert U,Poirier J

更新日期：1996-01-17 00:00:00

abstract：:Both orbital and attitude dynamics employ the method of variation of parameters. In a non-perturbed setting, the coordinates (or the Euler angles) are expressed as functions of the time and six adjustable constants called elements. Under disturbance, each such expression becomes ansatz, the "constants" being endowed w...

journal_title：Annals of the New York Academy of Sciences

authors： Efroimsky M

更新日期：2005-12-01 00:00:00

abstract：:The paper describes a comprehensive and objective evaluation of 2358 persons arrested in Philadelphia for driving while intoxicated. It was demonstrated that 63.8% of this population was involved with alcohol to an extent that a diagnosis of alcoholism was evident, and it is suggested that these persons are in need of...

journal_title：Annals of the New York Academy of Sciences

authors： Fine EW,Scoles P

更新日期：1976-01-01 00:00:00

abstract：:The W-curve is a numerical mapping algorithm that provides tertiary information content of long and short genomic sequences. The most popular genomic pattern recognition algorithms depend on string matching of the primary information content of short genomic sequences. Herein, we describe a way to define the fuzzy pro...

journal_title：Annals of the New York Academy of Sciences

authors： Cork DJ,Toguem A

更新日期：2002-12-01 00:00:00

abstract：:The molecular genetic basis of adaptive change in phenotype is a major outstanding issue in evolutionary biology. Evolutionary change in coat and plumage color is a promising system for making progress in this field. Most notably, recent work on the molecular genetic basis of hair and feather color has identified seve...

journal_title：Annals of the New York Academy of Sciences

authors： Mundy NI,Kelly J,Theron E,Hawkins K

更新日期：2003-06-01 00:00:00

abstract：:Whole body exposure of rabbits to microwave radiation causes a decrease in ascorbic acid in the lens. In our study, rabbit lenses maintained in culture medium (37 degrees C) were exposed to either pulsed or continuous wave S-band radiation for 10-15 min at power densities between 0 and 200 mW/cm-2. Total ascorbic acid...

journal_title：Annals of the New York Academy of Sciences

authors： Weiter JJ,Finch ED,Schulz W,Frattali V

更新日期：1975-02-28 00:00:00

abstract：:In the early 1970s carbohydrates (CHOs) were believed to induce overconsumption and excess fat deposition. They are now perceived to protect against these consequences. This paper evaluates the evidence for this change of interpretation by considering (1) the energy content of CHOs, (2) the energetic efficiency with w...

journal_title：Annals of the New York Academy of Sciences

authors： Stubbs RJ,Prentice AM,James WP

更新日期：1997-05-23 00:00:00

abstract：:Apoptosis protease-activating factor-1 (Apaf-1), which plays a central role in the formation of the apoptosome, is absent or poorly expressed (because of a transcriptional silencing by methylation) in a substantial percentage of metastatic melanomas and melanoma cell lines, which are unable to activate caspase-9 and e...

journal_title：Annals of the New York Academy of Sciences

authors： Del Bello B,Valentini MA,Comporti M,Maellaro E

更新日期：2003-12-01 00:00:00

abstract：:Although Lyme disease (LD) is the most common tick-borne disease in the United States, little is known about the frequency of and risk factors for infection with Borrelia burgdorferi in occupational groups. In 1986, we recruited primarily outdoor workers from six employee groups in southeastern New York where LD is en...

journal_title：Annals of the New York Academy of Sciences

authors： Smith PF,Benach JL,White DJ,Stroup DF,Morse DL

更新日期：1988-01-01 00:00:00

abstract：:The development of ustekinumab as a first-in-class anti-interleukin (IL) 12/23p40 therapeutic agent for psoriasis represents an important example of modern and rational drug design and development. Psoriasis is a chronic, systemic, immune-mediated skin disorder with considerable clinical, psychosocial, and economic bu...

journal_title：Annals of the New York Academy of Sciences

authors： Yeilding N,Szapary P,Brodmerkel C,Benson J,Plotnick M,Zhou H,Goyal K,Schenkel B,Giles-Komar J,Mascelli MA,Guzzo C

更新日期：2011-03-01 00:00:00

abstract：:The loss of mucus coat continuity and apoptosis have been shown in Helicobacter pylori (H. pylori)-infected gastric tissues. Blockade of p38 mitogen-activated kinase (MAPK) produced reversal in the LPS-induced reduction in mucin synthesis and apoptosis in gastric epithelial cells. This study investigates whether H. py...

journal_title：Annals of the New York Academy of Sciences

authors： Kim H,Seo JH,Kim KH

更新日期：2003-12-01 00:00:00