Abstract:
:Currently, it is known that several chemical agents used or generated by the oil industry are classified as mutagens and/or carcinogens. Among these we have gasoline, diesel, butane gas, styrene, benzene, chloroform, and others. Studies have verified that these chemicals have effects in fertility (abortions, sterility); produce various upheavals, such as dizziness, nausea, muscular pain; and produce chromosomal damage at the DNA level, which in the long or medium run, can develop into cancer and leukemia. The genetic damage in exposed individuals was measured by means of the comet test, chromosomal alterations test, and the study of the CYP 1A1 and MSH2 genes. These methods were applied to determine the genotoxicity of hydrocarbons and their residue in human beings. When conducting these tests on the blood samples of individuals exposed to hydrocarbons (workers of oil companies) and of a control population of the area of study and Quito, it was found that, in effect, the exposed individuals presented a greater amount of damage at the DNA level as well as at the chromosomal level than the individuals from the control populations (P< 0.001). Thus, it can be determined that populations that are exposed to hydrocarbons are susceptible to developing genetic damage. Therefore, risk groups can be determined in certain zones where the oil impact has been greater.
journal_name
Ann N Y Acad Scijournal_title
Annals of the New York Academy of Sciencesauthors
Paz-y-Miño C,López-Cortés A,Arévalo M,Sánchez MEdoi
10.1196/annals.1454.013subject
Has Abstractpub_date
2008-10-01 00:00:00pages
121-8eissn
0077-8923issn
1749-6632pii
NYAS1140013journal_volume
1140pub_type
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