Clinical relevance of serum amyloid A protein monitoring in urinary tract infections.

Abstract:

:We have evaluated the clinical relevance of monitoring acute phase proteins in severe urinary tract infection. Body temperature, white blood cell count, erythrocyte sedimentation rate, serum amyloid A protein (SAA), C-reactive protein (CRP), alpha-1-antichymotrypsin (ACT) and alpha-1-acid glycoprotein (AGP) were determined daily in sera from 18 treated patients. Two patterns of response could be identified: responders and non-responders whose therapy had to be changed. Mean values for each acute phase protein were calculated daily in both responders and non-responders. Statistical evaluation of the significance between the means for each protein was also performed on a daily basis and showed P < 0.01 for SAA and CRP on day 3, for ACT on day 5, and for AGP on day 6. SAA and CRP appear to be the most reliable markers for antimicrobial therapy monitoring in patients with urinary tract infections.

journal_name

Ann Clin Biochem

authors

Casl MT,Sabljar-Matovinović M,Kovacević S,Pocanić D,Preden-Kereković V,Jagarinec N

doi

10.1177/000456329303000308

subject

Has Abstract

pub_date

1993-05-01 00:00:00

pages

272-7

eissn

0004-5632

issn

1758-1001

journal_volume

30 ( Pt 3)

pub_type

杂志文章
  • Microalbuminuria in type 2 diabetic patients: a prospective follow-up study.

    abstract::We have studied 46 patients, 30 men and 16 women, with type 2 (non-insulin-dependent) diabetes in a follow-up period of 6-52 months (mean 30 months). The patients were consecutively entered in the study from the out-patient diabetic clinic. None had urinary tract infections nor proteinuria at entry. Investigations wer...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456329703400304

    authors: Friis T,Pedersen LR

    更新日期:1997-05-01 00:00:00

  • Measurement of conjugated diene lipids by derivative spectroscopy in heptane extracts of plasma.

    abstract::A series of experiments are described which show that second derivative spectroscopy can be used to quantify conjugated lipid dienes as markers of lipid peroxidation in heptane extracts of plasma from patients with rheumatoid arthritis, osteoarthritis, and healthy controls. Results obtained by this method gave reasona...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456329002700313

    authors: Situnayake RD,Crump BJ,Zezulka AV,Davis M,McConkey B,Thurnham DI

    更新日期:1990-05-01 00:00:00

  • Why do general practitioners request rheumatoid factor? A study of symptoms, requesting patterns and patient outcome.

    abstract:BACKGROUND:To investigate the reasons why general practitioners (GPs) request rheumatoid factor (RF) assays, we studied 200 consecutive requests for RF from general practice in 1995. METHOD:By means of an audit questionnaire, we studied 100 negative, 50 positive and 50 borderline RF results and compared these with the...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1258/000456303763046049

    authors: Sinclair D,Hull RG

    更新日期:2003-03-01 00:00:00

  • Hypopituitarism presenting as a mixed hyperlipidaemia.

    abstract::A case report is presented of a 37-year-old man who, largely by chance, was found to have a marked mixed hyperlipidaemia. As a teenager he had been treated for apparent idiopathic growth hormone deficiency, but had also never developed secondary sexual characteristics. Pituitary hormone measurement was now consistent ...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1258/0004563041201581

    authors: Kilpatrick ES,Patmore JE,Rowland-Hill C,Atkin SL

    更新日期:2004-07-01 00:00:00

  • Effect of storage of plasma and serum on enzymatic determination of non-esterified fatty acids.

    abstract::Many contradictory results have been published on the stability of total non-esterified fatty acids in blood, plasma and serum under different storage conditions. The present study was undertaken to investigate the stability of non-esterified fatty acids, measured with an enzymatic method, in samples of EDTA-treated p...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1258/0004563011900470

    authors: Menéndez LG,Fernández AL,Enguix A,Ciriza C,Amador J

    更新日期:2001-05-01 00:00:00

  • Rapidly rule out acute myocardial infarction by combining copeptin and heart-type fatty acid-binding protein with cardiac troponin.

    abstract:BACKGROUND:The rapid exclusion of acute myocardial infarction in patients with chest pain can reduce the length of hospital admission, prevent unnecessary diagnostic work-up and reduce the burden on our health-care systems. The combined use of biomarkers that are associated with different pathophysiological aspects of ...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/0004563215578189

    authors: Jacobs LH,van Borren M,Gemen E,van Eck M,van Son B,Glatz JF,Daniels M,Kusters R

    更新日期:2015-09-01 00:00:00

  • Atypicality revisited: further data on the effectiveness of the Mahalanobis distance in Down's syndrome screening.

    abstract::Further data suggesting that assessment of atypicality may be a valuable addition to Down's syndrome screening is presented, based on results from 1521 unaffected pregnancies and 190 chromosomally abnormal pregnancies. For a 1% increase in false positive rates (over the Down's screening-related false positives), it is...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456329703400314

    authors: Reynolds TM

    更新日期:1997-05-01 00:00:00

  • Quantitative analysis of elevated serum Golgi protein-73 expression in patients with liver diseases.

    abstract:BACKGROUND:Golgi protein-73 (GP73) is a newly identified candidate serum marker for liver diseases. The utility of this biomarker remains limited, largely due to the lack of quantitative information. The aims of this study were to quantify serum GP73 (sGP73) in healthy individuals and in patients with liver diseases, a...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1258/acb.2008.008088

    authors: Gu Y,Chen W,Zhao Y,Chen L,Peng T

    更新日期:2009-01-01 00:00:00

  • Influence of age, posture and intra-individual variation on plasma levels of atrial natriuretic peptide.

    abstract::This paper describes some factors to which attention should be paid when atrial natriuretic peptide (ANP) values are to be interpreted. Changing from the supine to the sitting position decreased ANP levels, while no further decrease was observed when the upright position was assumed. On the other hand, plasma renin ac...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456328902600604

    authors: Tan AC,Kloppenborg PW,Benraad TJ

    更新日期:1989-11-01 00:00:00

  • Circulating tumour DNA as a cancer biomarker.

    abstract::Measurement of genetically altered DNA shed from tumours into the circulation can potentially provide a new generation of blood-based cancer biomarkers. Compared with tissue DNA biomarkers which require surgery or biopsy, samples for circulating tumour DNA assays can be obtained with minimal inconvenience and at lower...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章,评审

    doi:10.1177/0004563218798401

    authors: Duffy MJ

    更新日期:2019-01-01 00:00:00

  • A method for the determination of sex hormone binding globulin using Concanavalin A-sepharose.

    abstract::A binding assay for sex hormone binding globulin (SHBG) has been developed in which SHBG is saturated with tritiated dihydrotestosterone (DHT). Separation of bound and free DHT is achieved by using Concanavalin A-Sepharose as a solid phase matrix. The method is described and its performance, including linearity, impre...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456329202900208

    authors: Whittaker JA,Cawood ML,Oakey RE

    更新日期:1992-03-01 00:00:00

  • The implementation of a system for managing analytical quality in networked laboratories.

    abstract:BACKGROUND:In a network of laboratories analytical variability between instruments, even of the same type, may exist for reasons beyond the control of laboratory staff. Controlling variability is a prerequisite for the application of shared reference ranges and for ensuring the transferability of patient test results. ...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1258/acb.2010.010005

    authors: Jassam N,Lindsay C,Harrison K,Thompson D,Bosomworth MP,Barth JH

    更新日期:2011-03-01 00:00:00

  • Kinetics of the antigen:antibody reaction. Light scattering and particle size measurement using photon correlation spectroscopy.

    abstract::Many techniques for the estimation of specific proteins measure light scattered by, or the turbidity of, suspensions of antigen:antibody aggregates formed in fluid-phase reactions. Although the shapes of reaction curves obtained are well documented, interpretation of the data in relation to the laws of light scatterin...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456328302000407

    authors: Deverill I,Lock RJ

    更新日期:1983-07-01 00:00:00

  • Radioimmunoassay of trypsin. A new aid in the assessment of pancreatic function.

    abstract::This review describes the development and application of a novel test to determine levels of human immunoreactive trypsin, an enzyme produced solely by the pancreas, in biological fluids. Being organ-specific, the assay of immunoreactive trypsin should be an ideal marker of pancreatic function, and this is supported b...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456327901600131

    authors: Stagg BH,Wood TP

    更新日期:1979-05-01 00:00:00

  • Glycosylated haemoglobin by affinity chromatography in diabetic and non-diabetic children.

    abstract::We have made an evaluation of glycosylated haemoglobin measurements by affinity chromatography in a paediatric population. Age-related reference values for non-diabetic infants and children are reported. A poor correlation (r = 0.24) was found between glycosylated haemoglobin values in 26 insulin-dependent diabetic ch...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456328602300407

    authors: van Heyningen C,Hanid TK,Hopkinson I

    更新日期:1986-07-01 00:00:00

  • Prognostic evaluation of serum long non-coding RNA H19 for endoscopic keyhole surgery or craniotomy in glioma.

    abstract:BACKGROUND:Our study aims to explore the effect of serum long non-coding RNA (lncRNA) H19 level on the long-term prognosis of endoscopic keyhole surgery or craniotomy for glioma. METHODS:A total of 264 glioma patients were selected. Patients were randomly divided into the Craniotomy-high H19 group, the Craniotomy-low ...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/0004563220941888

    authors: Shen L,Xu M,Wang Z,Yu Z

    更新日期:2020-09-01 00:00:00

  • Radioimmunoassay of sodium cromoglycate in human plasma.

    abstract::A sensitive radioimmunoassay method for sodium cromoglycate in human plasma is described. The lowest quantifiable concentration of sodium cromoglycate is 0.93 nmol/l when 0.1 ml plasma samples are analysed. Direct analysis of sodium cromoglycate concentrations in plasma samples collected up to several hours after the ...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456328302000105

    authors: Brown K,Gardner JJ,Lockley WJ,Preston JR,Wilkinson DJ

    更新日期:1983-01-01 00:00:00

  • Don't seek, don't find: The diagnostic challenge of Wernicke's encephalopathy.

    abstract::Wernicke's encephalopathy is caused by thiamine deficiency and has a range of presenting features, including gait disturbance, altered cognitive state, nystagmus and other eye movement disorders. In the past, Wernicke's encephalopathy was described almost exclusively in the alcohol-dependent population. However, in cu...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/0004563220939604

    authors: Kohnke S,Meek CL

    更新日期:2021-01-01 00:00:00

  • Evaluation of the Randox colorimetric serum copper and zinc assays against atomic absorption spectroscopy.

    abstract:BACKGROUND:Analysis of copper and zinc in serum is commonly performed using atomic absorption spectrometry (AAS); however, these methods are often not readily available in smaller laboratories. Randox colorimetric assays for copper and zinc in serum were evaluated on the Thermo Electron Data Pro analyser against flame ...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1258/acb.2009.008253

    authors: Beckett JM,Hartley TF,Ball MJ

    更新日期:2009-07-01 00:00:00

  • Assessment of tacrolimus and creatinine concentration collected using Mitra microsampling devices.

    abstract:BACKGROUND:Current practice requires regular venous blood samples for monitoring of tacrolimus concentrations post renal transplant requiring regular hospital visits. Mitra devices use volumetric absorptive microsampling technology and absorb a fixed amount of blood (10 μL) from a capillary blood sample. They are a via...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/0004563220948886

    authors: Marshall DJ,Kim JJ,Brand S,Bryne C,Keevil BG

    更新日期:2020-09-01 00:00:00

  • Determination of a Beckman Coulter AU turbidometric method-specific caeruloplasmin reference interval.

    abstract:BACKGROUND:Method-dependent variation of caeruloplasmin measurement is significant and necessitates the requirement for assay-specific reference intervals. Local determination becomes necessary in the absence of suitable published or manufacturer-quoted reference intervals. METHODS:Applicability of the Beckman Coulter...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/0004563221989360

    authors: Kaye OE,Cook P

    更新日期:2021-01-27 00:00:00

  • Comparison of blood glucose meters in a New Zealand diabetes centre.

    abstract:BACKGROUND:To assess the accuracy and precision of the Roche Performa and Medisense Optium Xceed (5 and 10 s reading) blood glucose meters. METHODS:Capillary blood samples were taken from 100 patients attending a diabetes centre and blood glucose measured on Roche Performa (n = 4) and Medisense Optium Xceed 5 s (n = 2...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1258/acb.2009.008193

    authors: Florkowski C,Budgen C,Kendall D,Lunt H,Moore MP

    更新日期:2009-07-01 00:00:00

  • An automated method for the analysis of urinary free catecholamines using ASTED and high-pressure liquid chromatography.

    abstract::A high-pressure liquid chromatography procedure for the measurement of free catecholamines in urine is described. 'On-line' sample preparation using a cartesian robot combined with the ASTED process ensures minimal operator intervention and reduced costs. ...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456328902600412

    authors: Green B,Cooper JD,Turnell DC

    更新日期:1989-07-01 00:00:00

  • Fibrin monomer complex in normal pregnant women: a potential thrombotic marker in pregnancy.

    abstract:BACKGROUND:Pregnancy represents a major risk factor for deep vein thrombosis (DVT). Most coagulation/fibrinolysis markers currently utilized change during pregnancy, and therefore they cannot accurately evaluate thrombotic events in pregnancy because the rate of false positive results is high. Fibrin monomer complex (F...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1258/000456307781646076

    authors: Onishi H,Kaniyu K,Iwashita M,Tanaka A,Watanabe T

    更新日期:2007-09-01 00:00:00

  • Assays for prolactin: guidelines for the provision of a clinical biochemistry service.

    abstract::This paper summarises the views of the authors on the provision of a prolactin assay service. We discuss the pathophysiology of prolactin secretion and the clinical indications that arise from that. We cover the rather complex issue of the definition of normal and elevated prolactin levels. From these considerations, ...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章,评审

    doi:10.1177/000456328602300603

    authors: Jeffcoate SL,Bacon RR,Beastall GH,Diver MJ,Franks S,Seth J

    更新日期:1986-11-01 00:00:00

  • A study of high-, middle- and low-molecular weight adiponectin in urine as a surrogate marker for early diabetic nephropathy using ultrasensitive immune complex transfer enzyme immunoassay.

    abstract::Background For the early identification of patients at risk of developing diabetic nephropathy, we have developed an ultrasensitive immune complex transfer enzyme immunoassay to measure adiponectin in urine. Methods We developed immune complex transfer enzyme immunoassay for adiponectin and measured urinary adiponecti...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/0004563217748681

    authors: Yamamoto M,Fujimoto Y,Hayashi S,Hashida S

    更新日期:2018-09-01 00:00:00

  • Pregnancy and inherited metabolic disorders: maternal and fetal complications.

    abstract::Some inherited metabolic disorders (IMDs) can cause significant complications during pregnancy, affecting the mother and/or the fetus. Although it appears that only a minority of IMDs have these effects, experience is still being acquired. For some disorders, patients will not have reached child-bearing age. Pregnanci...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章,评审

    doi:10.1258/000456302320314458

    authors: Preece MA,Green A

    更新日期:2002-09-01 00:00:00

  • Quality of commercially available controls in laser immunonephelometry.

    abstract::Lack of accuracy in expressing concentrations of specific proteins in different lots of Hyland calibrating reference and quality control materials, supplied for the Hyland PDQ laser nephelometer, prompted an attempt to find alternative and more reliable calibrating materials available commercially. Laser grade (Atlant...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456328001700403

    authors: Shulman G

    更新日期:1980-07-01 00:00:00

  • A systematic evaluation of immunoassay point-of-care testing to define impact on patients' outcomes.

    abstract::Background Point-of-care testing has been developed to provide rapid test results. Most published studies focus on analytical performance, neglecting its impact on patient outcomes. Objective To review the analytical performance and accuracy of point-of-care testing specifically planned for immunoassay and to evaluate...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/0004563217694377

    authors: Pecoraro V,Banfi G,Germagnoli L,Trenti T

    更新日期:2017-07-01 00:00:00

  • Assessment of the Beckman System 1.

    abstract::The System 1 produced results for glucose and urea which were precise and accurate. It proved suitable as a general laboratory instrument as it samples 28 mul of specimen, is able to calibrate itself, produces results in three minutes, and has the capacity to analyse 56 samples an hour. ...

    journal_title:Annals of clinical biochemistry

    pub_type: 杂志文章

    doi:10.1177/000456327701400179

    authors: Potezny N,Quelch J,Fuller B,Geary TD

    更新日期:1977-09-01 00:00:00