Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984.

abstract：PURPOSE:To determine the long-term cognitive and educational outcomes in children prospectively identified at the time of a first unprovoked seizure. METHODS:A cohort of children with a first unprovoked seizure was enrolled and followed for a mean of 15 years. Cognitive function and educational outcomes were determine...

journal_title：Epilepsia

authors： Sogawa Y,Masur D,O'Dell C,Moshe SL,Shinnar S

更新日期：2010-12-01 00:00:00

abstract：:Scrub typhus is an emerging infection, and there is little information about status epilepticus (SE) in scrub typhus. We report the clinical spectrum and outcome of SE in scrub typhus. In a 3-year prospective hospital-based observational study, all scrub typhus patients with SE were included. Scrub typhus was diagnose...

journal_title：Epilepsia

authors： Kalita J,Mani VE,Bhoi SK,Misra UK

更新日期：2016-07-01 00:00:00

abstract：:Genetic factors play a major role in the etiology of juvenile myoclonic epilepsy (JME), a common form of idiopathic generalized epilepsy, but so far, genes related to JME remain largely unknown. JME shares electroclinical features with Unverricht-Lundborg disease (progressive myoclonic epilepsy type 1; EPM1), a form o...

journal_title：Epilepsia

authors： Mumoli L,Tarantino P,Michelucci R,Bianchi A,Labate A,Franceschetti S,Marini C,Striano P,Gagliardi M,Ferlazzo E,Sofia V,Pennese L,Annesi G,Aguglia U,Guerrini R,Zara F,Gambardella A,Genetic Commission, Italian League Agai

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:The purpose of this study is to determine the sensibility of each imaging tool in identifying focal cortical dysplasia (FCD) in children and adolescents with epilepsy and to define the prognostic factors of pediatric and adolescent epilepsy surgery. METHODS:We identified 48 children with FCD who underwent rese...

journal_title：Epilepsia

authors： Kim YH,Kang HC,Kim DS,Kim SH,Shim KW,Kim HD,Lee JS

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:Patients with medically intractable epilepsy due to brain tumors may undergo resective surgery for treatment of both the tumor and the epilepsy. In this instance, the extent of surgical resection is sometimes guided by spikes recorded on intraoperative electrocorticography (ECoG). Whether spikes recorded by ele...

journal_title：Epilepsia

authors： Tran TA,Spencer SS,Javidan M,Pacia S,Marks D,Spencer DD

更新日期：1997-10-01 00:00:00

abstract：PURPOSE:This study investigated the impact of a treatment information package on patients being monitored for possible surgical treatment for temporal lobe epilepsy. METHODS:One hundred patients were randomly assigned to either a high- or low-information preparation condition. Levels of anxiety were tested soon after ...

journal_title：Epilepsia

authors： Andrewes D,Camp K,Kilpatrick C,Cook M

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To evaluate efficacy, tolerability, and safety of adjunctive brivaracetam (BRV) in patients with Unverricht-Lundborg disease (EPM1). METHODS:Two prospective, multicenter, double-blind, phase III trials (N01187/NCT00357669; N01236/NCT00368251) in patients (≥16 years) with genetically ascertained EPM1, showing...

journal_title：Epilepsia

authors： Kälviäinen R,Genton P,Andermann E,Andermann F,Magaudda A,Frucht SJ,Schlit AF,Gerard D,de la Loge C,von Rosenstiel P

更新日期：2016-02-01 00:00:00

abstract：:Mutations of the sodium channel subunit gene SCN2A have been described in families with benign familial neonatal-infantile seizure (BFNIS). We describe two large families with BFNIS and novel SCN2A mutations. The families had 12 and 9 affected individuals, respectively, with phenotypes consistent with BFNIS. Two mutat...

journal_title：Epilepsia

authors： Herlenius E,Heron SE,Grinton BE,Keay D,Scheffer IE,Mulley JC,Berkovic SF

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To evaluate the demographic impact of epilepsy a rural area of Africa. METHODS:A cohort study was conducted between 1991 and 2001 in the Mbam Valley (Cameroon) on two groups of subjects (one of persons with epilepsy, and the other of control individuals matched for sex, age, and village of residence). At the e...

journal_title：Epilepsia

authors： Kamgno J,Pion SD,Boussinesq M

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of antiepileptic drugs (AEDs; oxcarbazepine [OXC], levetiracetam [LEV], and lamotrigine [LTG]) on semen quality, sexual function, and sex hormones in male adults with epilepsy. METHODS:Individual treatment with OXC, LEV, or LTG was randomly assigned to 38 newly diagnosed male adult...

journal_title：Epilepsia

authors： Wu D,Chen L,Ji F,Si Y,Sun H

更新日期：2018-07-01 00:00:00

abstract：:The progressive myoclonus epilepsies (PMEs) are a group of rare genetic disorders previously shrouded in nosological confusion. Recent advances have clarified the features of these disorders and provided a rational approach to diagnosis. The major causes of PME are now known to be Unverricht-Lundborg disease, myoclonu...

journal_title：Epilepsia

authors： Berkovic SF,Cochius J,Andermann E,Andermann F

更新日期：1993-01-01 00:00:00

abstract：:Forty-five outpatients with chronic epilepsy with complex partial seizures (CPS) alone or associated with secondarily generalized tonic-clonic seizures (SGTCS) were treated with carbamazepine (CBZ) monotherapy. All patients had only a unilateral scalp electroencephalographic (EEG) focus. Left- (n = 29) and right- (n =...

journal_title：Epilepsia

authors： Defazio G,Lepore V,Specchio LM,Pisani F,Livrea P

更新日期：1991-09-01 00:00:00

abstract：PURPOSE:The purpose of this study was to clarify and compare the influence of surgical strategy on relief from seizures in patients with focal cortical dysplasia (FCD) and those with dysembryoplastic neuroepithelial tumor (DNT). METHODS:Six patients with FCD and five patients with DNT, all of whom underwent surgical r...

journal_title：Epilepsia

authors： Kameyama S,Fukuda M,Tomikawa M,Morota N,Oishi M,Wachi M,Kanazawa O,Sasagawa M,Kakita A,Takahashi H

更新日期：2001-01-01 00:00:00

abstract：:Sleep and epilepsy are interrelated. Understanding the relationship between epilepsy and sleep is important for optimizing management of the epilepsy patient in several ways. First, sleep modulates the expression of epileptic seizures and interictal epileptiform discharges. Second, epilepsy and its treatment influence...

journal_title：Epilepsia

authors： Malow BA

更新日期：2007-01-01 00:00:00

abstract：:Epilepsy syndromes occupy an important position in the current nosology of the epilepsies, describing and classifying seizure disorders with shared clinical and EEG features. Increasingly, this schema is being refined as new information becomes available and our understanding of etiology and presentation of each syndr...

journal_title：Epilepsia

authors： Duchowny M,Harvey AS

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:The selection of a minimal active sequence of erythropoietin allowed the design of peptide mimetics that exert beneficial effects in the central nervous system but lack an erythropoietic effect. Erythropoietin has been suggested as a promising therapeutic and prophylactic for epilepsies based on its neuroprotec...

journal_title：Epilepsia

authors： Seeger N,Zellinger C,Rode A,Roloff F,Bicker G,Russmann V,Fischborn S,Wendt H,Potschka H

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:In temporal lobe epilepsy (TLE), the thalamus is well known for its role in the propagation and spread of epileptiform activity. However, the integrity of thalamocortical functional connectivity (FC) in TLE and its relation to specific seizure patterns have not yet been determined. We address these issues wit...

journal_title：Epilepsia

authors： He X,Doucet GE,Sperling M,Sharan A,Tracy JI

更新日期：2015-10-01 00:00:00

abstract：:Rare individuals suffer epileptic seizures when they view certain images, particularly stripes. Contrast-threshold functions (the ability to see faint stripes of various widths) were determined for two pattern-sensitive brothers, and the epileptogenicity of various patterns was assessed for one of them. Sine wave grat...

journal_title：Epilepsia

authors： Soso MJ,Lettich E,Belgum JH

更新日期：1980-06-01 00:00:00

abstract：PURPOSE:Prior single-photon emission tomography studies showed losses of muscarinic acetylcholine receptor (MAChR) binding in patients with refractory mesial temporal lobe epilepsy. Experimental animal studies demonstrated transient losses of MAChR due to electrically induced seizures originating in the amygdala. Howev...

journal_title：Epilepsia

authors： Pennell PB,Burdette DE,Ross DA,Henry TR,Albin RL,Sackellares JC,Frey KA

更新日期：1999-01-01 00:00:00

abstract：:Reliably detecting focal seizures without secondary generalization during daily life activities, chronically, using convenient portable or wearable devices, would offer patients with active epilepsy a number of potential benefits, such as providing more reliable seizure count to optimize treatment and seizure forecast...

journal_title：Epilepsia

authors： Ryvlin P,Cammoun L,Hubbard I,Ravey F,Beniczky S,Atienza D

更新日期：2020-11-01 00:00:00

abstract：:Despite over 80 years of use, the ketogenic diet (KD) has never been tested in a blinded manner. Twenty children with intractable Lennox-Gastaut syndrome (LGS) were fasted 36 h and then randomized to receive the classic KD in conjunction with a solution containing either 60 g/day of glucose or saccharin. Parents and p...

journal_title：Epilepsia

authors： Freeman JM,Vining EP,Kossoff EH,Pyzik PL,Ye X,Goodman SN

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:In one third of patients, seizures remain after epilepsy surgery, meaning that improved preoperative evaluation methods are needed to identify the epileptogenic zone. A potential framework for such a method is network theory, as it can be applied to noninvasive recordings, even in the absence of epileptiform ...

journal_title：Epilepsia

authors： Nissen IA,Stam CJ,Reijneveld JC,van Straaten IE,Hendriks EJ,Baayen JC,De Witt Hamer PC,Idema S,Hillebrand A

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to systematically review the literature on the interictal language profile in adult patients with epilepsy. METHODS:An extensive literature search was performed using MEDLINE, Embase, PsycINFO, Cochrane Central Register of Controlled Trials, PASCAL, and PSYNDEXplus databases. Ke...

journal_title：Epilepsia

authors： Bartha-Doering L,Trinka E

更新日期：2014-10-01 00:00:00

abstract：PURPOSE:Mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE-HS) is the most common of the antiepileptic drug (AED)-resistant seizure syndromes that are remediable mostly with surgery, although a small group of patients have benign prognosis with fewer seizures. Material-specific memory impairment ...

journal_title：Epilepsia

authors： Ozkara C,Hanoğlu L,Keskinkiliç C,Yeni N,Aysal F,Uzan M,Ozyurt E,Karaağaç N

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:Despite national guidelines supporting surgical referral in drug-resistant epilepsy, it is hypothesized that surgery is underutilized. We investigated the volumes of lobectomy/amygdalohippocampectomy surgeries over time and examined differences in outcomes between (1) high-volume (HV), middle-volume (MV), and...

journal_title：Epilepsia

authors： Kwon CS,Blank L,Mu L,Jetté N

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:To validate and translate the English version of the Neurologic Depression Disorders Inventory in Epilepsy (NDDI-E) into Spanish as a screening instrument for major depressive episodes (MDE) for patients with epilepsy from Argentina and Uruguay. METHODS:One hundred fifty-five consecutive outpatients with ep...

journal_title：Epilepsia

authors： Thomson AE,Calle A,Fontela ME,Yepez L,Muñoz Giacomelli F,Jáuregui A,Racosta JM,Kanner AM

更新日期：2014-02-01 00:00:00

abstract：:Since its introduction into clinical practice in 1999, levetiracetam, the S enantiomer of piracetam, has rapidly found a secure place, initially in the therapy of partial onset seizures and subsequently in the treatment of idiopathic generalized epilepsies (IGE). It has many of the properties of an "ideal" antiepilept...

journal_title：Epilepsia

authors： Grünewald R

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:To describe the correlations between spiking pattern and EEG power spectrum frequency in DBA/2J mice, a model for murine absence seizures, after gamma-aminobutyric acid (GABA)(B) modulation. METHODS:The animals were first tested with the GABA(B) agonist l-baclofen followed by the GABA(B) antagonist SCH 50911. ...

journal_title：Epilepsia

authors： Marrosu F,Santoni F,Fà M,Puligheddu M,Barberini L,Genugu F,Frau R,Manunta M,Mereu G

更新日期：2006-03-01 00:00:00

abstract：:Development of tolerance (i.e., the reduction in response to a drug after repeated administration) is an adaptive response of the body to prolonged exposure to the drug, and tolerance to antiepileptic drugs (AEDs) is no exception. Tolerance develops to some drug effects much more rapidly than to others. The extent of ...

journal_title：Epilepsia

authors： Löscher W,Schmidt D

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:Nine patients affected by schizencephaly were analyzed, and the epileptologic findings prospectively studied, to define the relations between the anatomic brain malformations and clinical outcome. METHODS:The schizencephaly was diagnosed by means of magnetic resonance imaging (eight cases) or computed tomograp...

journal_title：Epilepsia

authors： Granata T,Battaglia G,D'Incerti L,Franceschetti S,Spreafico R,Battino D,Savoiardo M,Avanzini G

更新日期：1996-12-01 00:00:00