Reduced thalamocortical functional connectivity in temporal lobe epilepsy.

abstract：:The development of the Neuropsychological Battery for Epilepsy is presented. The tests are designed to be helpful in the evaluation of adult epileptics. The battery consists of General Measures which include tests in the areas of intellectual functioning, emotional status, and lateral dominance. The development of a s...

journal_title：Epilepsia

authors： Dodrill CB

更新日期：1978-12-01 00:00:00

abstract：:Successful treatment of hypothalamic hamartoma (HH) can result in the resolution of its sequelae including epilepsy and rage attacks. Risks and morbidity of open surgical management of this lesion have motivated the development of laser interstitial thermal therapy (LITT) as a less invasive treatment approach to the d...

journal_title：Epilepsia

authors： Du VX,Gandhi SV,Rekate HL,Mehta AD

更新日期：2017-06-01 00:00:00

abstract：:Pregnancy is associated with characteristic changes in the disposition of antiepileptic drugs; recent findings on this aspect of drug utilization are presented. In one study involving 48 pregnancies, the mean level-dose ratio of phenytoin decreased by 34%. In another study of 111 patients, phenytoin clearance increase...

journal_title：Epilepsia

authors： Levy RH,Yerby MS

更新日期：1985-01-01 00:00:00

abstract：:Deletions and duplications/amplifications of the α1-sodium channel subunit (SCN1A) gene occur in about 12% of patients with Dravet syndrome (DS) who are otherwise mutation-negative. Such genomic abnormalities cause loss of function, with severe phenotypes, reproductive disadvantage and, therefore, sporadic occurrence....

journal_title：Epilepsia

authors： Guerrini R,Cellini E,Mei D,Metitieri T,Petrelli C,Pucatti D,Marini C,Zamponi N

更新日期：2010-12-01 00:00:00

abstract：:The distribution of seizure types was investigated in an epidemiological survey of 1,220 patients over 15 years of age. Classification of clinically dominant seizure type according to the International Classification of Epileptic Seizures (ICES) was possible in 1,005 cases (82.5%). Fifty-six percent of patients had pa...

journal_title：Epilepsia

authors： Keränen T,Sillanpää M,Riekkinen PJ

更新日期：1988-01-01 00:00:00

abstract：:During a 10-year period, 203 traffic accidents were suspected of being caused by epilepsy; 155 of them definitely caused by seizures were selected for study. The seizures of 75% were psychomotor; in 12% the seizure was the first, and only 4% of the rest had reported that they had epilepsy when they applied for a licen...

journal_title：Epilepsia

authors： van der Lugt PJ

更新日期：1975-12-01 00:00:00

abstract：PURPOSE:The present study was undertaken to clarify the effects of (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA), a metabotropic glutamate receptor (mGluR) 1 antagonist, (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate ((2R,4R)-APDC), a mGluR2/3 agonist, and L-(+)-2-amino-4-phosphonobutyric acid (L-AP4), a mGluR4/8 agonis...

journal_title：Epilepsia

authors： Watanabe Y,Kaida Y,Fukuhara S,Takechi K,Uehara T,Kamei C

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:Mycoplasma pneumoniae, a common respiratory pathogen, has been implicated as an etiology of encephalitis, but there are few reports about it and postencephalitic epilepsy. This study aimed to investigate clinical factors, electroencephalography, and neuroradiologic features of M. pneumoniae-related encephalitis...

journal_title：Epilepsia

authors： Lin JJ,Hsia SH,Wu CT,Wang HS,Lin KL

更新日期：2011-11-01 00:00:00

abstract：:Dipropylacetic acid (VPA, valproic acid) has been quantified in plasma and semen from rabbits and man using a new gas-liquid chromatographic assay. The drug assay is rapid, sensitive and free from interference by VPA metabolites. The beta phase half-life of VPA in rabbits after an i.v. dose (50 mg/kg) was 56 +/- 6 min...

journal_title：Epilepsia

authors： Swanson BN,Harland RC,Dickinson RG,Gerber N

更新日期：1978-12-01 00:00:00

abstract：:Study of patients with temporal lobe epilepsy and generalized epilepsy revealed no overall seizure type differences, nor overall age-at-onset effects, on MMPI measures of psychopathology. However, statistically significant interactions between seizure type and age at onset were obtained on several MMPI measures, and s...

journal_title：Epilepsia

authors： Hermann BP,Schwartz MS,Karnes WE,Vahdat P

更新日期：1980-02-01 00:00:00

abstract：:A questionnaire survey was conducted in Japan to investigate the causes and prevalence of death related to Dravet syndrome. The questionnaire was delivered to 246 hospitals at which physicians were treating childhood epilepsy to gain information about the total number of patients with Dravet syndrome and the prevalenc...

journal_title：Epilepsia

authors： Sakauchi M,Oguni H,Kato I,Osawa M,Hirose S,Kaneko S,Takahashi Y,Takayama R,Fujiwara T

更新日期：2011-04-01 00:00:00

abstract：:Why some patients with seizures are successfully treated with antiepileptic drugs (AEDs) and others prove medically intractable is not known. Inadequate intraparenchymal drug concentration is a possible mechanism of resistance to AEDs. The multiple drug resistance gene (MDR1) encodes P-glycoprotein, an energy-dependen...

journal_title：Epilepsia

authors： Tishler DM,Weinberg KI,Hinton DR,Barbaro N,Annett GM,Raffel C

更新日期：1995-01-01 00:00:00

abstract：:Temporal lobe epilepsy (TLE) is the most common focal epilepsy in adults. TLE has a high chance of becoming medically refractory, and as such, is frequently considered for further evaluation and surgical intervention. Up to 30% of TLE cases, however, can have normal ("nonlesional" or negative) magnetic resonance imagi...

journal_title：Epilepsia

authors： Muhlhofer W,Tan YL,Mueller SG,Knowlton R

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:To determine the lateralizing value of the clinical manifestations of seizures in patients with temporal lobe epilepsy (TLE), we made a retrospective videotape analysis of complex partial seizures (CPS) in 55 patients who underwent temporal lobectomy and were seizure-free postoperatively for >2 years. METHODS:...

journal_title：Epilepsia

authors： Marks WJ Jr,Laxer KD

更新日期：1998-07-01 00:00:00

abstract：:Twenty-seven patients with medically refractory paroxysmal disorders underwent EEG-video-audio (EVA) monitoring in an inpatient neurology-neurosurgery unit over 1-15 (mean 8.9) days. Fast visual review of all EEG records (5,784 h) and subsequent analysis of synchronized EVA patterns demonstrated a total of 208 partial...

journal_title：Epilepsia

authors： Pierelli F,Chatrian GE,Erdly WW,Swanson PD

更新日期：1989-09-01 00:00:00

abstract：:To evaluate the impact of epileptiform discharges (EDs) that do not occur within seizure patterns--such as spikes, sharp waves or spike waves--on cognitive function and to discuss the circumstances under which treatment of EDs might be considered. Methods used in this article is "Review of the literature". EDs may dis...

journal_title：Epilepsia

authors： Sánchez Fernández I,Loddenkemper T,Galanopoulou AS,Moshé SL

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:This study was designed to quantify the relation between expressions of NMDA receptor (NMDAR) subunits (1 and 2A/B) and the epileptogenicity in human focal cortical dysplasia. METHODS:Immunoblotting and immunoprecipitation were used to quantify these receptor subunits in tissue resected from EEG-verified epile...

journal_title：Epilepsia

authors： Mikuni N,Babb TL,Ying Z,Najm I,Nishiyama K,Wylie C,Yacubova K,Okamoto T,Bingaman W

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Stress is a known trigger for seizures in patients with epilepsy (PWE). However, the association between stress and seizures has not been thoroughly investigated. In December 2019, an outbreak of coronavirus disease (COVID-19) occurred in Wuhan, Hubei province, China, causing tremendous collateral stress. Thi...

journal_title：Epilepsia

authors： Huang S,Wu C,Jia Y,Li G,Zhu Z,Lu K,Yang Y,Wang F,Zhu S

更新日期：2020-09-01 00:00:00

abstract：:In January 2019, a new plant-derived purified cannabidiol preparation, approved by the US Food and Drug Administration, became commercially available for patients ≥2 years old with Lennox-Gastaut syndrome or Dravet syndrome. Among our patients who were prescribed the new cannabidiol formulation, we observed several ca...

journal_title：Epilepsia

authors： McNamara NA,Dang LT,Sturza J,Ziobro JM,Fedak Romanowski EM,Smith GC,Joshi SM,Leber SM,Carlson M,Robertson P,Shellhaas RA

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:Neuropsychological studies suggest frontal lobe dysfunctions in patients with juvenile myoclonic epilepsy (JME). In this study we investigated whether an underlying mechanism could be a regional neuronal damage not visible with structural magnetic resonance (MR), but detectable with magnetic resonance spectrosc...

journal_title：Epilepsia

authors： Savic I,Lekvall A,Greitz D,Helms G

更新日期：2000-03-01 00:00:00

abstract：:Surgery for seizures arising from the rolandic area can be performed effectively, and accurate mapping of eloquent regions may improve seizure and functional outcome. Noninvasive cortical mapping is, however, hardly feasible in young children. We studied two children with epileptogenic focal cortical dysplasia (FCD) t...

journal_title：Epilepsia

authors： Barba C,Montanaro D,Frijia F,Giordano F,Blümcke I,Genitori L,De Masi F,Guerrini R

更新日期：2012-08-01 00:00:00

abstract：:A recent systematic synthesis of qualitative research demonstrated that patients with psychogenic nonepileptic seizures (PNES) often experience unsatisfactory encounters with health care practitioners (HCPs). It is important to understand such interactions from the perspective of those responsible for delivering care....

journal_title：Epilepsia

authors： Rawlings GH,Reuber M

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:This study investigated the impact of a treatment information package on patients being monitored for possible surgical treatment for temporal lobe epilepsy. METHODS:One hundred patients were randomly assigned to either a high- or low-information preparation condition. Levels of anxiety were tested soon after ...

journal_title：Epilepsia

authors： Andrewes D,Camp K,Kilpatrick C,Cook M

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:To determine the prevalence of epilepsy and seizures in the Navajo. METHODS:We studied 226,496 Navajo residing in the Navajo Reservation who had at least one medical encounter between October 1, 1998 and September 30, 2002. We ascertained and confirmed cases in two phases. First, we identified patients with In...

journal_title：Epilepsia

authors： Parko K,Thurman DJ

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:The objective of this study was the isobolographic evaluation of the interactions between the novel antiepileptic drug (AED) gabapentin (GBP) and a number of other AEDs against electroconvulsion-induced convulsions in mice. METHODS:Electroconvulsions were produced by means of an alternating current (ear-clip e...

journal_title：Epilepsia

authors： Borowicz KK,Swiader M,Luszczki J,Czuczwar SJ

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:We investigated the incidence of well-directed violent behavior and suicide attempts in patients with temporal lobe epilepsy, with special attention to postictal psychosis. METHODS:We compared 57 episodes of postictal psychosis with 62 episodes of acute interictal (or alternative) psychosis and with 134 comple...

journal_title：Epilepsia

authors： Kanemoto K,Kawasaki J,Mori E

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:Magnetoencephalography (MEG)/magnetic source imaging (MSI) is a noninvasive functional neuroimaging procedure used to localize language-specific regions in the brain. The Wada test, or intracarotid amobarbital procedure (IAP), is the gold standard in determining speech/language lateralization for presurgical pl...

journal_title：Epilepsia

authors： Doss RC,Zhang W,Risse GL,Dickens DL

更新日期：2009-10-01 00:00:00

abstract：:Determining a prognosis for functional recovery after prolonged status epilepticus can be difficult. Prior case studies have shown that despite seizure control, functional outcomes are typically poor unless a reversible cause is identified. Herein we present a case of idiopathic status epilepticus with a surprisingly ...

journal_title：Epilepsia

authors： Standley K,Abdulmassih R,Benbadis S

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:This study examined the influence of two psychosocial variables mediating between disease severity and quality of life (QoL) in epilepsy; social support and mastery (measured by locus of control and self-efficacy). A model placing these two variables as mediators between disease severity and QoL was tested with...

journal_title：Epilepsia

authors： Amir M,Roziner I,Knoll A,Neufeld MY

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:To develop a better understanding of mechanisms of seizures and long-term epileptogenesis using neurocysticercosis. METHODS:A workshop was held bringing together experts in epilepsy and epileptogenesis and neurocysticercosis. RESULTS:Human neurocysticercosis and parallel animal models offer a unique opportu...

journal_title：Epilepsia

authors： Nash TE,Mahanty S,Loeb JA,Theodore WH,Friedman A,Sander JW,Singh G,Cavalheiro E,Del Brutto OH,Takayanagui OM,Fleury A,Verastegui M,Preux PM,Montano S,Pretell EJ,White AC Jr,Gonzales AE,Gilman RH,Garcia HH

更新日期：2015-02-01 00:00:00