Abstract：
:This report describes a new polymorphism, in intron 3 of the p53 gene, which consists of a single repeat of 16 nucleotides, absent in the published wild-type p53 gene sequence. In the Caucasian population tested (n = 82), 28% of individuals were heterozygotes for this polymorphism. Using PCR-based analysis, we were able to demonstrate p53 allelic losses in three of six breast tumors from heterozygote patients tested.
journal_name
Oncogenejournal_title
Oncogeneauthors
Lazar V,Hazard F,Bertin F,Janin N,Bellet D,Bressac Bsubject
Has Abstractpub_date
1993-06-01 00:00:00pages
1703-5issue
6eissn
0950-9232issn
1476-5594journal_volume
8pub_type
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