Antimicrobial strategies in the prevention of dental caries.

Abstract:

:Antimicrobial agents, applied either professionally or delivered from dentifrices or mouthwashes, could reduce caries by controlling plaque formation, suppressing cariogenic species, or by inhibiting bacterial metabolism. Chlorhexidine has proven anticaries activity; other agents might also prevent caries by means of their antiplaque properties. Sugar substitutes stabilize the microflora by reducing the number of acid challenges to plaque and stimulating saliva flow; some also have antimicrobial properties, especially against mutans streptococci. Vaccines have been prepared from purified antigens of mutans streptococci. These vaccines confer protection in non-human primates, but have yet to be tested in a human clinical trial.

journal_name

Caries Res

journal_title

Caries research

authors

Marsh PD

doi

10.1159/000261607

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

72-6

eissn

0008-6568

issn

1421-976X

journal_volume

27 Suppl 1

pub_type

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    更新日期:2008-01-01 00:00:00

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    更新日期:2000-03-01 00:00:00

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  • Scanning electron microscopy of softened enamel.

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    authors: Keltjens HM,Schaeken MJ,van der Hoeven JS,Hendriks JC

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