Abstract:
:Scottish children have one of the highest levels of caries experience in Europe. Only 33% of 5-year-old children in Dundee who developed caries in their first permanent molars by 7 brushed their teeth twice a day. High-caries-risk children should benefit if they brush more often with fluoridated toothpaste. The aim of this clinical trial was to determine the reduction in 2-year caries increment that can be achieved by daily supervised toothbrushing on school-days with a toothpaste containing 1,000 ppm fluoride (as sodium monofluorophosphate) and 0.13% calcium glycerophosphate, combined with recommended daily home use, compared to a control group involving no intervention other than 6-monthly clinical examinations. Five hundred and thirty-four children, mean age 5.3, in schools in deprived areas of Tayside were recruited. Each school had two parallel classes, one randomly selected to be the brushing class and the other, the control. Local mothers were trained as toothbrushing supervisors. Children brushed on school-days and received home supplies. A single examiner undertook 6-monthly examinations recording plaque, caries (D(1) level), and used FOTI to supplement the visual caries examination. For children in the brushing classes, the 2-year mean caries increment on first permanent molars was 0.81 at D(1) and 0.21 at D(3) compared to 1.19 and 0.48 for children in the control classes (significant reductions of 32% at D(1) and 56% at D(3)). In conclusion, high-caries-risk children have been shown to have significantly less caries after participating in a supervised toothbrushing programme with a fluoridated toothpaste.
journal_name
Caries Resjournal_title
Caries researchauthors
Curnow MM,Pine CM,Burnside G,Nicholson JA,Chesters RK,Huntington Edoi
10.1159/000063925subject
Has Abstractpub_date
2002-07-01 00:00:00pages
294-300issue
4eissn
0008-6568issn
1421-976Xpii
63925journal_volume
36pub_type
临床试验,杂志文章,随机对照试验相关文献
CARIES RESEARCH文献大全abstract::This in vitro study evaluated the protective effect of fluoride varnishes containing sodium trimetaphosphate (TMP) against dentin erosion and abrasion. Specimens of coronal dentin were divided into: placebo, 2.5% NaF, 5% NaF, 2.5% NaF + 5% TMP, and 5% NaF + 5% TMP groups (n =24/group). After single application of the ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000505179
更新日期:2020-01-01 00:00:00
abstract::To study the effects of prolonged and exclusive breast-feeding on dental caries, we followed up children participating in the Promotion of Breastfeeding Intervention Trial (PROBIT), a cluster-randomized trial of a breast-feeding promotion intervention based on the WHO/UNICEF Baby-Friendly Hospital Initiative. A total ...
journal_title:Caries research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000108596
更新日期:2007-01-01 00:00:00
abstract::The effects of milk and kappa-casein rinses on the salivary pellicle formed on hydroxyapatite discs carried in the mouth were studied. SDS-PAGE analyses revealed an increase in the number of proteins deposited onto the discs carried after the water and milk rinses only. Scanning electron microscopy studies revealed th...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016558
更新日期:2000-01-01 00:00:00
abstract::This study measured dental caries in children after cessation of a 30-month randomised clinical trial in which the intervention group received supervised toothbrushing once a day at school with 1,000 ppm fluoride toothpaste and a home support package encouraging twice-daily toothbrushing. The non-intervention group di...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000104800
更新日期:2007-01-01 00:00:00
abstract::Previously, a mixed culture chemostat system was used to demonstrate that the pH generated from carbohydrate metabolism, rather than carbohydrate availability per se, was responsible for the shifts observed in the oral microflora which are associated with high carbohydrate diets and the development of dental caries. T...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016487
更新日期:1998-01-01 00:00:00
abstract::The distribution of fluoride in human dental calculus was investigated using a mechanical sampling technique and the fluoride electrode. The fluoride concentrations were highest at the outer surface of dental calculus and, then fell to a plateau for the interior of the calculus, rising again as the tooth surface was a...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261549
更新日期:1993-01-01 00:00:00
abstract::The aim of the study was to examine the relationship between oral hygiene level and caries experience in 14-year-olds using fluoride dentifrices on a regular basis. Oral hygiene expressed as Gingival Bleeding Points (GBP) was recorded in 267 individuals in the county of Lillehammer in Norway. Total caries experience a...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262133
更新日期:1996-01-01 00:00:00
abstract::The 5-year incidence of caries was studied in a random sample of 60-, 70- and 80-year-old inhabitants of Göteborg, with 69, 51 and 28 individuals in the different age groups. One aim of the study was to introduce a root caries index (DMFRS%) in which the missing root surfaces are taken into account. This study, as wel...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262408
更新日期:1997-01-01 00:00:00
abstract::Diagnosis of occlusal caries is difficult from visual and radiographic examination. The use of electrical resistance measurement has been described previously and reported to be a potentially sensitive alternative technique. This is possibly due to the decreased resistance of carious pits and fissures. The aim of this...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262152
更新日期:1996-01-01 00:00:00
abstract::The aim of this study was to test the clinical effects of preventive regimens using fluoride and chlorhexidine on caries development in abutment teeth in patients with overdentures. 30 patients with immediate overdentures were distributed at random among three experimental groups. In these groups three different gels ...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000261298
更新日期:1990-01-01 00:00:00
abstract::The quality of radiographic diagnosis of occlusal carries was examined with special attention to the diagnosis of lesions in dentin. Eighty-four extracted teeth, most of them with occlusal caries of different severity and some apparently sound, were radiographed. For validation purposes, the lesion depths were recorde...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261640
更新日期:1994-01-01 00:00:00
abstract::Erosion of the buccal incisor enamel, most frequent in the upper jaw, has been associated with excessive oral exposure to citric acid-containing foodstuffs. The aim of the study was to determine the retention of citric acid at different sites in the mouth after a standardized exposure. Thirty-four normal subjects rins...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262116
更新日期:1995-01-01 00:00:00
abstract::This study analyzed the effects of fluoride varnishes supplemented with sodium trimetaphosphate (TMP) on the remineralization of caries-like lesions in vitro. Bovine enamel discs were selected through surface hardness (SH) and caries-like lesions were induced. SH was again determined and the blocks were divided into 7...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000356308
更新日期:2014-01-01 00:00:00
abstract::The remineralization of whole human dentine treated with a neutral EDTA solution was investigated: the treatment periods were 15, 30 and 120 min. From the literature it is known that EDTA removes noncollagenous proteins (NCPs) from dentine powders. In order to extract more phosphoproteins from dentine lesions, in part...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016529
更新日期:1999-07-01 00:00:00
abstract::The aim of this clinical study was to investigate the acid resistance of enamel lesions remineralized in situ by a sugar-free chewing gum containing casein phosphopeptide-amorphous calcium phosphate nanocomplexes (CPP-ACP: Recaldent). The study utilized a double-blind, randomized, crossover design with two treatments:...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000080585
更新日期:2004-11-01 00:00:00
abstract::A split-mouth randomized clinical trial was carried out to assess the effectiveness of sealants in preventing carious ICDAS (International Caries Detection and Assessment System) 3-6 lesions within a 2-year follow-up. We evaluated the effectiveness of 2 types of resin-based sealants, with and without fluoride, their r...
journal_title:Caries research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000486426
更新日期:2018-01-01 00:00:00
abstract::The aim was to describe the prevalence and incidence of caries lesions in relation to the placement and replacement of amalgam and non-metal fillings in a randomly selected adult Danish population. In 1997 and in 2003, 470 individuals underwent a full-mouth radiographic survey. All recordings were based on radiographs...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000217861
更新日期:2009-01-01 00:00:00
abstract::This study investigated the role of a matrix metalloproteinase (MMP) inhibitor (CHX 2%) in the development of secondary caries wall lesions in different interface conditions with small (run 1) and wider gaps (run 2). Dentin discs were restored and pretreated with or without CHX 2%. In run 1, interfaces were made with ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000490195
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) acts as a salivary biomimetic that provides bioavailable calcium and phosphate ions to augment fluoride-mediated remineralisation of early caries lesions. However, there are indications that it may also have beneficial ecological effects on the oral...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000499869
更新日期:2019-01-01 00:00:00
abstract::The level of Streptococcus mutans in saliva was determined by a dip-slide method in 841 13-year-old children in order to identify children with high caries risk. For each child, the flow rate of saliva was determined. Caries scores were obtained from Public Dental Health records. A sucrose intake score was calculated ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261110
更新日期:1988-01-01 00:00:00
abstract::Twenty-four-hour urine samples were collected from each of thirteen 5- to 6-year-old children both under customary conditions of fluoride intake (i.e. usual diet including milk containing 0.5 mg fluoride and usual oral hygiene procedures with fluoride toothpaste) and during a 4-day study period in which their customar...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000047466
更新日期:2001-07-01 00:00:00
abstract::The aim of our study was to determine whether the structure of glucans formed by glucosyltransferase from Streptococcus sanguinis (GtfSs) on a surface differ from those formed in solution and to explore the effects of antiserum to Gtfs, control normal rabbit serum, starch hydrolysates (STH) and dextran on S. sanguinis...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000047434
更新日期:2001-01-01 00:00:00
abstract::In this study the effect of X-ray irradiation on demineralization of bovine dental enamel in vitro was investigated. Enamel specimens were irradiated with 72 Gy and subsequently demineralized (140 h) under reproducible constant composition conditions at pH = 5 in the presence of methylhydroxydiphosphonate (MHDP). Micr...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261106
更新日期:1988-01-01 00:00:00
abstract::The aim of the present study was to develop transverse microradiography (TMR) in order to quantitatively assess the influence of artificial saliva and orange juice on the erosion of bovine enamel. Bovine incisors were sectioned sagittally into two equal halves. Each half was coated with acid-resistant nail varnish exc...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016471
更新日期:1998-01-01 00:00:00
abstract::The aim was to study the effect of substitution of invert sugar for sucrose, in combination with fluoride varnish (Duraphat) treatment twice a year, on caries development in preschool children. One hundred and eighty-seven 4-years-olds were divided randomly into four sugar groups: (1) sucrose (S), (2) sucrose-Duraphat...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000261381
更新日期:1991-01-01 00:00:00
abstract::The effect of 2-O-stearoyl glycerol-1,3-bisphosphate (Glydip) on caries lesion formation in root surfaces of sound human third molars was investigated in vitro. For this purpose parts of the root surfaces were treated with Glydip. Adjacent parts of the surfaces were not treated and served as control. Lesions were obta...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261374
更新日期:1991-01-01 00:00:00
abstract::The effect of supplementing the diet or drinking water with lactate dehydrogenase (LDH) on the formation of caries lesions in rats was investigated. Addition of LDH [20 and 5 mg/kg in the high-sucrose (65%) diet, 2 and 1 U/ml in the drinking water (LDH-specific activity 735 U/mg solid)] resulted in significant reducti...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261236
更新日期:1990-01-01 00:00:00
abstract::In 1995, a dental survey was performed among adults aged 25-54 in the Dutch city of 's-Hertogenbosch. A similar study was performed in the same city in 1983 and the aim of the present study was to describe trends in oral health from 1983 to 1995. National data show that the percentage of edentulous persons aged 30-39 ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016448
更新日期:1998-01-01 00:00:00
abstract:AIM:The aim of the study was to evaluate if pH indicator strips could be used for measurements of plaque pH acidogenicity in situ. METHOD:Interproximal plaque pH was measured before and up to 60 min after a 10% sucrose rinse in 30 healthy volunteers using pH indicator strips and the microtouch method in parallel. RES...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000315273
更新日期:2010-01-01 00:00:00
abstract::To investigate the efficacy of atraumatic restorative treatment (ART) sealants vs. no sealant in preventing the development of dentine caries lesions in first permanent molars over a period of 3 years. A total of 187 schoolchildren (aged 6-8 years) from a low-income population presenting the 4 first permanent molars w...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000506466
更新日期:2020-12-16 00:00:00