Abstract:
:The effect of 2-O-stearoyl glycerol-1,3-bisphosphate (Glydip) on caries lesion formation in root surfaces of sound human third molars was investigated in vitro. For this purpose parts of the root surfaces were treated with Glydip. Adjacent parts of the surfaces were not treated and served as control. Lesions were obtained by demineralization with an acetate buffer of pH 5.0. It was found that Glydip had no inhibiting effect on the rate of lesion formation. Additionally, pretreatments were performed with lauryl sulphate, a chloroform-methanol mixture, an aqueous solution of sodium hypochlorite, and collagenase prior to the treatment with Glydip to enhance the accessibility of the tissue for Glydip. None of these pretreatments or combinations of them revealed an inhibiting effect of Glydip on the rate of caries lesion formation. This result is in contrast to the effect of Glydip on the demineralization of enamel.
journal_name
Caries Resjournal_title
Caries researchauthors
Borggreven JM,Driessens FC,Hoeks TL,Zwanenburg Bdoi
10.1159/000261374subject
Has Abstractpub_date
1991-01-01 00:00:00pages
264-7issue
4eissn
0008-6568issn
1421-976Xjournal_volume
25pub_type
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