Abstract:
:The aim of the study was to determine the pharmacokinetics of a new hydroxyapatite-Eudragit RS100 diffusion-controlled fluoride-releasing system designed for intraoral use with a 0.15 mg F(-)/day release for a 1-month period. Matrix tablets, each containing 18 mg of sodium fluoride, were bonded to the buccal surface of the first maxillary molar teeth of 20 subjects (age 20-23 years). Morning and evening salivary and urinary samples were collected 5 days before the study and every day for the 1st week, then once a week for 1 month. Fluoride ion measurements were done using the microdiffusion method. The salivary and urinary fluoride concentrations were significantly raised during the treatment period (p < 0.05). Morning salivary fluoride levels were higher than evening salivary fluoride levels (p < 0.05) whereas evening urinary fluoride levels were higher than morning urinary fluoride levels (p < 0.05). The statistically significant increase in salivary fluoride levels indicates a caries-preventive role for this device.
journal_name
Caries Resjournal_title
Caries researchauthors
Altinova YB,Alaçam A,Aydin A,Sanisoglu SYdoi
10.1159/000084797subject
Has Abstractpub_date
2005-05-01 00:00:00pages
191-4issue
3eissn
0008-6568issn
1421-976Xpii
84797journal_volume
39pub_type
杂志文章相关文献
CARIES RESEARCH文献大全abstract::Little is known about the long-term effects of fluoride-releasing materials on carious dentine in vivo. The aim was to investigate the 2-year influence of a resin-modified glass ionomer cement (RM-GIC) and amalgam on the bacteriological counts of carious dentine that remained under class I restorations. To enable a sp...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000016506
更新日期:1999-01-01 00:00:00
abstract::The study of plaque biofilms in the oral cavity is difficult as plaque removal inevitably disrupts biofilm integrity precluding kinetic studies involving the penetration of components and metabolism of substrates in situ. A method is described here in which plaque is formed in vivo under normal (or experimental) condi...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000262398
更新日期:1997-01-01 00:00:00
abstract:AIM:To evaluate how concentration and pH of TiF(4) influence the erosion-protective effect. METHODS:Specimens were treated with a TiF(4) solution: (1) 0.5 M F, pH 1.2, (2) 0.05 M F, pH 2.1, (3) 0.5 M F, pH 2.1, or (4) 0.05 M F, pH 1.2; then, they were exposed to HCl. RESULTS:After 2 min, the proportions of the area c...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000324155
更新日期:2011-01-01 00:00:00
abstract::Mutans streptococci (MS) and lactobacillus (LB) counts (CRT Bacteria chair-side test) were compared and correlated with the respective caries experience (DMF) of cystic fibrosis (CF) homozygotes (n = 20), CF heterozygotes (n = 20) and healthy controls (n = 20). Each group of subjects was divided into two equal age gro...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000047483
更新日期:2001-11-01 00:00:00
abstract::This longitudinal study aimed to investigate variables associated with colonisation of mutans streptococci (MS) compared with lactobacilli (LB) colonisation in a cohort of children (n = 214) from the time of first tooth eruption at approximately 6 months until 24 months of age. Repeated plaque and salivary samples wer...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000339089
更新日期:2012-01-01 00:00:00
abstract::The aim was to study the salivary fluoride (F) concentration and plaque pH recovery on the chewing and the non-chewing side of the dentition during and after chewing 1 piece of chewing gum containing 0.25 mg F as NaF. Ten subjects refrained from toothbrushing for 3 days. On the fourth day, they rinsed for 1 min with 1...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000262420
更新日期:1997-01-01 00:00:00
abstract::The aim was to study the effect of three fluoride-releasing restorative materials on sound enamel of approximal teeth under cariogenic conditions intraorally. Bovine enamel slabs were paired with four hemispherical samples from each of three test materials (Ketac Molar, ESPE; Vitremer, F-2000, both from 3M) and one co...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000047456
更新日期:2001-05-01 00:00:00
abstract::To exert anticaries effects, probiotics are described to inhibit growth and biofilm formation of cariogenic bacteria such as Streptococcus mutans (SM). We screened 8 probiotics and assessed how SM growth or biofilm formation inhibition affects cariogenicity of probiotic-SM mixed-species biofilms in vitro. Growth inhib...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000452960
更新日期:2017-01-01 00:00:00
abstract::Comprehensive oral examinations carried out over a period of about 10 years on participants in the Veterans Administration Dental Longitudinal Study were evaluated to identify teeth extracted during this time and to ascertain the apparent reason for these extractions. The study population included 736 dentulous adult ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261178
更新日期:1989-01-01 00:00:00
abstract:AIM:To assess the effect of protein-containing toothpastes on the progression of dental erosion in situ (with pellicle) and in vitro (without pellicle). METHODS:A combined split-mouth (extraoral water or toothpaste brushing) and crossover (type of toothpaste) setup was used. Two protein-containing (high/low concentrat...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000344016
更新日期:2013-01-01 00:00:00
abstract::The purpose of this study was to investigate the demineralization of dentin by measuring changes in the velocity of the sonic longitudinal waves transmitted through this substrate. One group of samples was immersed in demineralization solution for 10 min twice a day and then stored in artificial saliva. Two additional...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000099319
更新日期:2007-01-01 00:00:00
abstract::Bone morphogenetic proteins (BMPs) play an important role during the initial process of enamel development and therefore may play a role in caries susceptibility. The purpose of this study was to evaluate the association between the polymorphisms in the BMP2, BMP4 and BMP7 genes and their association with caries exper...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000371715
更新日期:2015-01-01 00:00:00
abstract::The microradiographic mineral content and birefringence in water and Thoulet's solution were measured at selected points in sections of caries-like lesions. Birefringence was not related to mineral content in sound superficial enamel immersed in Thoulet's solution or in the lesion body immersed in water. For the surfa...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261508
更新日期:1993-01-01 00:00:00
abstract::The purpose of the study was to determine whether adding calcium lactate to chewing gum containing xylitol enhances remineralization of enamel surfaces using an early caries lesion model. Enamel slabs were cut from human extracted sound teeth and artificial subsurface lesions created within each. Half the enamel slabs...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000088905
更新日期:2006-01-01 00:00:00
abstract::This study aimed to analyse if the erosion-protective potential of the salivary pellicle is different between female and male subjects. Bovine enamel and dentin specimens (each n = 3) were exposed to the oral cavity of healthy female or male volunteers (each n = 25, females: 25.8 ± 3.5 years, males: 26.7 ± 4.0 years) ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000500046
更新日期:2019-01-01 00:00:00
abstract::The purpose of this study was to evaluate the influence of enamel defects in the development of dental caries and their association with feeding practices and oral health behaviors in a cohort study of low-socioeconomic children from birth to 36 months of age in northeastern Brazil. Subjects were registered at birth a...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000093188
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND/AIMS:To investigate the association between birth weight and infant growth during the first year of life and the occurrence of developmental defects of enamel (DDE) in permanent dentition. METHODS:A random sample of 668 12-year-old students was recruited from a birth cohort. Permanent incisors and first mol...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000381425
更新日期:2015-01-01 00:00:00
abstract::The literature on the erosive potential of drinks and other products is summarised, and aspects of the conduct of screening tests as well as possible correlations of the erosive potential with various solution parameters are discussed. The solution parameters that have been suggested as important include pH, acid conc...
journal_title:Caries research
pub_type: 杂志文章,评审
doi:10.1159/000325917
更新日期:2011-01-01 00:00:00
abstract::Tea decoctions prepared from a number of black and green teas inhibited amylase in human saliva. Black teas gave higher levels of inhibition than green teas, and removal of tea tannins with gelatin led to the loss of inhibitory activity from all decoctions. Streptococcal amylase was similarly inhibited by tea decoctio...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016458
更新日期:1998-01-01 00:00:00
abstract::The dentine-pulp complex shows a broad spectrum of responses to caries of the dental tissues, which represents a summation of injury, defence and repair events taking place. The relative importance of these various events will reflect both the extent of disease activity and metabolic state of the tissues. This review ...
journal_title:Caries research
pub_type: 杂志文章,评审
doi:10.1159/000063930
更新日期:2002-07-01 00:00:00
abstract::This study aimed to determine the reliability and accuracy of the ICDAS and radiographs in detecting and estimating the depth of proximal lesions on extracted teeth. The lesions were visible to the naked eye. Three trained examiners scored a total of 132 sound/carious proximal surfaces from 106 primary teeth and 160 s...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000324439
更新日期:2011-01-01 00:00:00
abstract::The aim was to describe the prevalence and incidence of caries lesions in relation to the placement and replacement of amalgam and non-metal fillings in a randomly selected adult Danish population. In 1997 and in 2003, 470 individuals underwent a full-mouth radiographic survey. All recordings were based on radiographs...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000217861
更新日期:2009-01-01 00:00:00
abstract::The aim was to study the effect of substitution of invert sugar for sucrose, in combination with fluoride varnish (Duraphat) treatment twice a year, on caries development in preschool children. One hundred and eighty-seven 4-years-olds were divided randomly into four sugar groups: (1) sucrose (S), (2) sucrose-Duraphat...
journal_title:Caries research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000261381
更新日期:1991-01-01 00:00:00
abstract::Ion-sensitive field-effect transistor (ISFET) pH electrodes were used to monitor changes in plaque pH at the base of artificial occlusal surface fissures and at interproximal sites. Bovine enamel was used to construct fissures (1.5 x 0.1 x 1.0 mm) containing a small ISFET electrode. The fissures were fixed to carrier ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000261220
更新日期:1989-01-01 00:00:00
abstract::Acidic fluoride solutions may reduce dental erosion. The aim of this study was to compare the effect of different acidic fluoride solutions on enamel dissolution using an established in vivo model. When possible 4 anterior teeth (255 teeth in a total of 67 subjects) were isolated and exposed to 0.01 M citric acid. The...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000209345
更新日期:2009-01-01 00:00:00
abstract::The relationship between dental caries and sense of coherence (SOC) has not been substantiated in children and adolescents, particularly among those with a low socioeconomic status. The aim of this study was to investigate the association between SOC and dental caries in schoolchildren from a low socioeconomic backgro...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000493537
更新日期:2019-01-01 00:00:00
abstract::This study examines cellular and microradiographic findings in thin, undemineralized sections of 46 cavitated lesions, that were clinically well-defined with respect to lesion activity and estimated lesion age at extraction time. The progressive stages of surface breakdown ranged from enamel cavitation to larger denti...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000016495
更新日期:1999-01-01 00:00:00
abstract::In vitro experiments could demonstrate that only negligible amounts of fluoride are necessary to promote remineralization of incipient caries lesions. From the clinical point of view, there is evidence that only under certain circumstances is a stabilization of the surface zone of an incipient caries lesion the true m...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000049112
更新日期:2001-01-01 00:00:00
abstract::In recent years a strategy of selective, symptom-based intervention of carious primary teeth has been developed amongst some British general dental practitioners. Practice-based studies appear to provide evidence that policies of restoration of symptomless carious primary teeth do not confer any significant benefits a...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000314677
更新日期:2010-01-01 00:00:00
abstract::This study analyzed the effects of fluoride varnishes supplemented with sodium trimetaphosphate (TMP) on the remineralization of caries-like lesions in vitro. Bovine enamel discs were selected through surface hardness (SH) and caries-like lesions were induced. SH was again determined and the blocks were divided into 7...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000356308
更新日期:2014-01-01 00:00:00