Mineralisation of developmentally hypomineralised human enamel in vitro.

Abstract:

:Molar-incisor hypomineralisation (MIH) is a problematic and costly condition. Caries remineralising agents are often recommended for MIH management despite the lack of evidence that these lesions have the capacity for increasing their mineral content. Following surface layer removal ± NaOCl pre-treatment and 14-day exposure to a CPP-ACFP solution at pH 5.5, MIH lesions were analysed using transverse microradiography and polarised light microscopy. Lesions were highly variable but treatment with the remineralising solution increased mineral content (1,828 ± 461 vol% min · µm, %R = 17.7 ± 5.7) and porosity decreased demonstrating the proof of concept that the mineral content of developmentally hypomineralised enamel can be improved after eruption.

journal_name

Caries Res

journal_title

Caries research

authors

Crombie FA,Cochrane NJ,Manton DJ,Palamara JE,Reynolds EC

doi

10.1159/000346134

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

259-63

issue

3

eissn

0008-6568

issn

1421-976X

pii

000346134

journal_volume

47

pub_type

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