Progression of interdigital infections from simplex to complex.

Abstract:

:The dynamics of symptomatic toe web infections often involve an ecologic interplay in which an initial dermatophyte infection provides a hospitable niche for subsequent colonization by bacteria. Several studies suggest that exacerbation of a mild dermatophyte infection (dermatophytosis simplex) can arise in the occlusive environment of the toe web space. Fungal infection induces damage to the stratum corneum, which allows overgrowth of resident bacteria and maceration, itching, and often malodor at the site (dermatophytosis complex). Because fungi frequently elaborate antibacterial substances, the superinfecting bacteria generally are resistant to penicillin and other antibiotics. A flourishing bacterial superinfection may mask the underlying fungal cause, making it difficult to obtain a positive fungal culture.

journal_name

J Am Acad Dermatol

authors

Leyden JJ

doi

10.1016/s0190-9622(09)80301-0

subject

Has Abstract

pub_date

1993-05-01 00:00:00

pages

S7-S11

issue

5 Pt 1

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(09)80301-0

journal_volume

28

pub_type

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