Severe sialadenitis: a new complication of drug reaction with eosinophilia and systemic symptoms.

Abstract:

BACKGROUND:Drug cutaneous reaction and isolated cases of parotitis induced by terbinafine have been reported. OBSERVATION:We report a case of drug reaction with eosinophilia and systemic symptoms induced by terbinafine associated with a severe sialadenitis and a complete sicca syndrome. Evolution was protracted with a slow recovery of the rash but sicca syndrome persisted with only a very mild improvement at 6 months. CONCLUSION:Liver, kidneys, lungs, and heart are the organs the most frequently involved in drug reaction with eosinophilia and systemic symptoms. Salivary and lacrimal glands can also be severely involved in the course of drug reaction with eosinophilia and systemic symptoms.

journal_name

J Am Acad Dermatol

authors

Abecassis S,Roujeau JC,Bocquet H,Copie-Bergman C,Radier C,Revuz J,Cosnes A

doi

10.1016/j.jaad.2004.06.023

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

827-30

issue

5

eissn

0190-9622

issn

1097-6787

pii

S0190962204016573

journal_volume

51

pub_type

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