Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events.

abstract：:Continuous dopamine (DA) stimulation is a therapeutic approach that applies to the treatment of motor fluctuations due to pulsatile DA stimulation in Parkinson's disease (PD), to cure the abuse of drugs, such as cocaine or amphetamine (which produce short-lasting peaks of extracellular DA), and as a safe therapeutic a...

journal_title：Annals of the New York Academy of Sciences

authors： Biagioni F,Busceti CL,Molinaro G,Battaglia G,Giorgi FS,Ruggieri S,Fornai F

更新日期：2006-08-01 00:00:00

abstract：:Invasive plants cause substantial economic and environmental damage throughout the world. However, eradication of most invasive species is impossible and, in some cases, undesirable. An alternative is to slow the spread of an invasive species, which can delay impacts or reduce their extent. We identify three main area...

journal_title：Annals of the New York Academy of Sciences

authors： Caplat P,Coutts S,Buckley YM

更新日期：2012-02-01 00:00:00

abstract：:NAFTA and GATT have specified that we must base import decisions on sound scientific information. This includes the use of risk assessment procedures to justify excluding or restricting the international movement of either live animals or products from animals. Procedures and techniques have been described for calcula...

journal_title：Annals of the New York Academy of Sciences

authors： Metcalf HE,Blackwell JH,Acree JA

更新日期：1996-07-23 00:00:00

abstract：:A few years after the first description of free-circulating DNA in plasma and serum, the detection of tumor-associated overexpressed mRNA in plasma was also reported. This observation has been confirmed and it seems to be clear that the presence of free-circulating RNA is a ubiquitous phenomenon. In this short review ...

journal_title：Annals of the New York Academy of Sciences

authors： Fleischhacker M

更新日期：2006-09-01 00:00:00

abstract：:The effects on ex vivo LDL resistance to oxidation and biomarkers of in vivo oxidative stress in response to 3-month dietary vitamin E restriction to 25% of recommended intake and 2-month unrestricted dietary intake and supplementation with 800 IU/d were studied in 100 healthy, nonsmoking 20-75-year-old volunteers. Si...

journal_title：Annals of the New York Academy of Sciences

authors： Winklhofer-Roob BM,Meinitzer A,Maritschnegg M,Roob JM,Khoschsorur G,Ribalta J,Sundl I,Wuga S,Wonisch W,Tiran B,Rock E,VITAGE Study Group.

更新日期：2004-12-01 00:00:00

abstract：:Neuromodulation denotes controlled electrical stimulation of the central or peripheral nervous system. The three forms of neuromodulation described in this paper-deep brain stimulation, vagus nerve stimulation, and transcranial magnetic stimulation-were chosen primarily for their demonstrated or potential clinical use...

journal_title：Annals of the New York Academy of Sciences

authors： Andrews RJ

更新日期：2003-05-01 00:00:00

abstract：:SNAP-25 (synaptosomal-associated protein of 25 kDa) is a plasma membrane protein that, together with syntaxin and the synaptic vesicle protein VAMP/synaptobrevin, forms the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) docking complex for regulated exocytosis. SNAP-25 also modulates dif...

journal_title：Annals of the New York Academy of Sciences

authors： Corradini I,Verderio C,Sala M,Wilson MC,Matteoli M

更新日期：2009-01-01 00:00:00

abstract：:Over 450 peer-reviewed papers containing the keyword Aspergillus fumigatus were published in 2011. Although this method may be an impossible task, I have selected three clusters of papers describing exciting recent advances in research on A. fumigatus. The first is the novel approach of in vivo imagining of experiment...

journal_title：Annals of the New York Academy of Sciences

authors： Osherov N

更新日期：2012-12-01 00:00:00

abstract：:CYP21A2 genotyping remains an important element in the diagnosis and management of congenital adrenal hyperplasia, and establishing accurate genotype-phenotype correlations has facillitated adequate genetic counseling and prenatal management for at-risk families. Despite extensive efforts to establish a clear genotype...

journal_title：Annals of the New York Academy of Sciences

authors： Elmougy F,Sharaf S,Hafez M,Khattab A,Abou-Yousef H,Elsharkawy M,Baz H,Ekladious S,Sherif B,Musa N,Elshiwy Y,Afif A,Abdullatif M,Thabet G,Rady N,Ibrahim A,Soliman H

更新日期：2018-03-01 00:00:00

abstract：:A body of information obtained by experiments with intact tissues, isolated cells, and sarcolemmal vesicles indicates, beyond a reasonable doubt, that a specific Na(+)-Ca2+ exchange system exists in vascular smooth muscle. However, its role in the regulation of cytosolic free-Ca2+ concentration and cell tension under ...

journal_title：Annals of the New York Academy of Sciences

authors： Matlib MA

更新日期：1991-01-01 00:00:00

abstract：:In keeping with the inflammatory paradigm of abdominal aortic aneurysm (AAA) pathophysiology, in vitro studies suggest that aneurysms secrete the proinflammatory cytokine interleukin-6 (IL-6). Circulating IL-6 levels are higher in patients with AAA with elevated circulating IL-6 an independent risk factor for cardiova...

journal_title：Annals of the New York Academy of Sciences

authors： Dawson J,Cockerill G,Choke E,Loftus I,Thompson MM

更新日期：2006-11-01 00:00:00

abstract：:The fate of alpha-hemoglobin chains and the cause of membrane protein defects in thalassemic erythrocytes have been studied in: (1) human beta-thalassemia syndromes, (2) mouse beta-thalassemia, and (3) normal human erythrocytes loaded with purified alpha-hemoglobin chains. The similarity and differences observed in th...

journal_title：Annals of the New York Academy of Sciences

authors： Rouyer-Fessard P,Scott MD,Leroy-Viard K,Garel MC,Bachir D,Galacteros F,Beuzard Y

更新日期：1990-01-01 00:00:00

abstract：:A meta-analysis of 14 clinical studies with RRR- or all-rac-alpha-tocopherol (83,800 subjects) was performed to evaluate whether RRR and all-rac differ in cardiovascular efficacy based on those clinical endpoints that are most consistently documented in the publications of the studies. Odds ratios of treatment versus ...

journal_title：Annals of the New York Academy of Sciences

authors： Kraemer K,Koch W,Hoppe PP

更新日期：2004-12-01 00:00:00

abstract：:Acute viral infection of humans induces virus-specific serum antibody production that often persists for decades. To better understand the nature of this long-term antiviral antibody response, we studied antiviral antibody production of mice acutely infected with lymphocytic choriomeningitis virus (LCMV). Although thi...

journal_title：Annals of the New York Academy of Sciences

authors： Slifka MK,Ahmed R

更新日期：1996-10-25 00:00:00

abstract：:Venous or arterial thrombosis, abortion, and the presence of antiphospholipid antibodies (aPL) define the criteria for the antiphospholipid syndrome (APS). A heterogeneous group of antibodies against phospholipids and plasma proteins may influence several coagulation pathways and lead to thrombophilia. We investigated...

journal_title：Annals of the New York Academy of Sciences

authors： Miesbach W,Matthias T,Scharrer I

更新日期：2005-06-01 00:00:00

abstract：:Rehabilitation aims to lessen the physical and cognitive impairments and disabilities of patients with stroke, multiple sclerosis, spinal cord or brain injury, and other neurologic diseases. Conventional approaches beyond compensatory adjustments to disability may be augmented by applying some of the myriad experiment...

journal_title：Annals of the New York Academy of Sciences

authors： Dobkin BH

更新日期：2004-12-01 00:00:00

abstract：:Venous thromboembolic events, such as pulmonary embolism, deep venous thrombosis, and portal vein thrombosis, have been observed in adult thalassemia patients, mainly in beta-thalassemia intermedia. The clinical findings are consistent with the observation of several alterations that indicate a state of activation of ...

journal_title：Annals of the New York Academy of Sciences

authors： Cappellini MD,Grespi E,Cassinerio E,Bignamini D,Fiorelli G

更新日期：2005-01-01 00:00:00

abstract：:Glucagon and the glucagon-like peptides (GLP-1 and GLP-2) share a common evolutionary origin and are triplication products of an ancestral glucagon exon. In mammals, a standard scenario is found where only a single proglucagon-derived peptide set exists. However, fish and amphibians have either multiple proglucagon ge...

journal_title：Annals of the New York Academy of Sciences

authors： Ng SY,Lee LT,Chow BK

更新日期：2010-07-01 00:00:00

abstract：:Despite neuropathological and electrophysiological evidence for the involvement of parahippocampal structures in temporal lobe epilepsy (TLE), little attention has been paid to morphometric changes in these structures, and the relation of these changes to TLE. We performed high-resolution MRI volumetric analysis to ex...

journal_title：Annals of the New York Academy of Sciences

authors： Bernasconi N,Bernasconi A,Caramanos Z,Andermann F,Dubeau F,Arnold DL

更新日期：2000-06-01 00:00:00

abstract：:Three vaccine stabilates of Theileria parva, of which sporozoites are being used against East Coast fever, were characterized by immunological and molecular biology techniques before being used for a national vaccination campaign in Kenya. T. parva Marikebuni stabilates 316 and 3014, and T. parva Lanet were used in th...

journal_title：Annals of the New York Academy of Sciences

authors： Sparagano OA,Zanaa O,Ambrose N

更新日期：1998-06-29 00:00:00

abstract：:McCune-Albright syndrome (MAS) is caused by postzygotic somatic activating mutations of GNAS and is classically characterized by the clinical triad of peripheral precocious puberty, café-au-lait pigmentation, and polyostotic fibrous dysplasia. It can also present with other hyperfunctioning endocrinopathies, including...

journal_title：Annals of the New York Academy of Sciences

authors： Chatty P,Khattab A,Marshall I

更新日期：2020-03-01 00:00:00

abstract：:Questions about music's evolution and functions have long excited interest among scholars. More recent theoretical accounts have stressed the importance of music's social origins and functions. Autism and Williams syndrome, neurodevelopmental disorders supposedly characterized by contrasting social and musical phenoty...

journal_title：Annals of the New York Academy of Sciences

authors： Heaton P,Allen R

更新日期：2009-07-01 00:00:00

abstract：:After fertilization, the next major hurdle for human reproduction is trophoblast differentiation, which is required for implantation, followed in lockstep by rapid assembly of these embryonic cells into a functional placenta. During this process, cytotrophoblast stem cells invade the uterus, anchoring the conceptus to...

journal_title：Annals of the New York Academy of Sciences

authors： Zhou Y,Genbacev O,Fisher SJ

更新日期：2003-05-01 00:00:00

abstract：:Preeclampsia is the disorder of pregnancy with the highest rate of both maternal and neonatal morbidity and mortality. The maternal syndrome is characterized by oxidative stress and activation of the vascular endothelium that may originate from placental release of lipid peroxidation products, cytokines, and micropart...

journal_title：Annals of the New York Academy of Sciences

authors： Poston L,Raijmakers M,Kelly F

更新日期：2004-12-01 00:00:00

abstract：:Air particulate activity over all of the Northern Hemisphere reached its highest levels since the termination of nuclear weapons testing--sometimes up to 1 million times higher than before the Chernobyl contamination. There were essential changes in the ionic, aerosol, and gas structure of the surface air in the heavi...

journal_title：Annals of the New York Academy of Sciences

authors： Yablokov AV,Nesterenko VB,Nesterenko AV

更新日期：2009-11-01 00:00:00

abstract：:The Cervico-ocular reflex (COR), which depends on proprioceptive afferents from neck muscles to the vestibular nucleus, makes little contribution to the stabilization of gaze in humans. If labyrinthine function is lost because of disease, however, the COR may increase in gain and assume greater importance in generatin...

journal_title：Annals of the New York Academy of Sciences

authors： Carmona S,Nieto D

更新日期：2005-04-01 00:00:00

abstract：:This brief review is designed to highlight the limitations of our knowledge given the difficulties in simulating the in vivo condition in models established in vitro and ex vivo. Despite this uncertainty, mounting evidence indicates that the GPIIb-IIIa receptor mediates crucial platelet functions and that control over...

journal_title：Annals of the New York Academy of Sciences

authors： Coller BS

更新日期：1987-01-01 00:00:00

abstract：:The present epidemiological data support and extend previous evidence in men and animals. Thus, a poor plasma status of vitamin C (less than 23 microM = 0.4 mg/dl) and/or of cholesterol-standardized vitamin E (less than 20-21.5 microM = 9 mg/l) occurs in westernized countries with an increased risk of IHD. A poor stat...

journal_title：Annals of the New York Academy of Sciences

authors： Gey KF,Stähelin HB,Puska P,Evans A

更新日期：1987-01-01 00:00:00

abstract：:Current tuberculosis (TB) therapies take too long and the regimens are complex and subject to adverse effects and drug-drug interactions with concomitant medications. The emergence of drug-resistant TB strains exacerbates the situation. Drug discovery for TB has resurged in recent years, generating compounds (hits) wi...

journal_title：Annals of the New York Academy of Sciences

authors： Mdluli K,Kaneko T,Upton A

更新日期：2014-09-01 00:00:00

abstract：:It has previously been shown that stimulation of muscarinic m1 or m3 receptors can, by generating diacylglycerol (DAG) and activating protein kinase C (PKC), accelerate the breakdown of the amyloid precursor protein (APP) to form soluble, non-amyloidogenic peptides (APPs). This relationship has been demonstrated in hu...

journal_title：Annals of the New York Academy of Sciences

authors： Lee RK,Jimenez J,Cox AJ,Wurtman RJ

更新日期：1996-01-17 00:00:00