Does maternal diabetes delay fetal pulmonary maturity?

Abstract:

OBJECTIVE:The purpose of our study was to determine whether a relationship exists between diabetic glucose control and the immaturity rate of fetal pulmonary maturity test results. STUDY DESIGN:One thousand consecutive women who had fetal pulmonary maturity testing before delivery were studied. Diabetic patients were categorized according to whether their diabetes was well controlled or poorly controlled, then compared to the nondiabetic population on the basis of amniocentesis results. RESULTS:Pregnant women with poorly controlled diabetes had a significantly higher risk of immature fetal lung profiles at amniocentesis than did pregnant women without diabetes. Pregnant women with well-controlled diabetes were not significantly different from the nondiabetic population. There was no difference between gestational and pregestational diabetic pregnancies. CONCLUSIONS:Timing of fetal pulmonary maturation is linked to the level of maternal glucose control in diabetic pregnancies. Adequate glucose control may lower the risk of fetal pulmonary immaturity to that seen in the nondiabetic population.

journal_name

Am J Obstet Gynecol

authors

Piper JM,Langer O

doi

10.1016/s0002-9378(12)90819-4

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

783-6

issue

3 Pt 1

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(12)90819-4

journal_volume

168

pub_type

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