A history of preeclampsia identifies women who have underlying cardiovascular risk factors.

Abstract:

OBJECTIVE:The objective of this study was to prospectively assess physical and biochemical cardiovascular risk markers in women who had developed preeclampsia (PE) at 1 year postpartum. STUDY DESIGN:Following an overnight fast, previously PE (n = 70) and normotensive women (n = 70) had weight and blood pressure recorded and levels of morning blood for insulin, glucose, C-reactive protein, lipids, cholesterol, and urine for microalbumin and creatinine measured. Body mass index, homeostatic model assessment index, and incidence of metabolic syndrome were determined. RESULTS:At 1 year postpartum, markers of cardiovascular disease were different between the groups. There were also differences in the number of women with abnormal values. Mathematical modeling of cardiovascular event risk suggests that PE increases the risk by 2- to 3-fold; the risk was greatest for women with severe PE. CONCLUSION:The development of PE is 1 of the earliest clinically identifiable markers of a woman's heightened risk of cardiovascular disease.

journal_name

Am J Obstet Gynecol

authors

Smith GN,Walker MC,Liu A,Wen SW,Swansburg M,Ramshaw H,White RR,Roddy M,Hladunewich M,Pre-Eclampsia New Emerging Team (PE-NET).

doi

10.1016/j.ajog.2008.06.035

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

58.e1-8

issue

1

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(08)00646-7

journal_volume

200

pub_type

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