Ionic mechanisms mediating oscillatory membrane potentials in wide-field retinal amacrine cells.

abstract：:The properties of the vestibuloocular reflex (VOR) when the axis of rotation is behind the eyes and fixation of a near target is required were studied in the monkey. The magnitude of VOR gain in each eye was found to be above 1.0 and near the ideal value for stabilizing a retinal image. Evidence that this large VOR ga...

journal_title：Journal of neurophysiology

authors： Viirre E,Tweed D,Milner K,Vilis T

更新日期：1986-08-01 00:00:00

abstract：:An imbalance between the strengths of excitatory and inhibitory synaptic inputs has been proposed as the cellular basis of autism and related neurodevelopmental disorders. Previous studies examining spontaneous levels of excitatory and inhibitory neurotransmission in the forebrain regions of methyl-CpG-binding protein...

journal_title：Journal of neurophysiology

authors： Nelson ED,Bal M,Kavalali ET,Monteggia LM

更新日期：2011-07-01 00:00:00

abstract：:The performance of neural codes to represent attributes of sensory signals has been evaluated in the vertebrate peripheral and central nervous system. Here, we determine how information signaled by populations of neurons is modified by plasticity. Suprathreshold neuronal responses from a large number of neurons were r...

journal_title：Journal of neurophysiology

authors： Pita-Almenar JD,Ranganathan GN,Koester HJ

更新日期：2011-09-01 00:00:00

abstract：:The spinal network coordinating locomotion is comprised of a core of glutamate and glycine interneurons. This network is modulated by several transmitter systems including spinal GABA interneurons. The purpose of this study is to explore the contribution of GABAergic neurons to the regulation of locomotor burst freque...

journal_title：Journal of neurophysiology

authors： Schmitt DE,Hill RH,Grillner S

更新日期：2004-10-01 00:00:00

abstract：:Synchronization of local and distributed neuronal assemblies is thought to underlie fundamental brain processes such as perception, learning, and cognition. In neurological disease, neuronal synchrony can be altered and in epilepsy may play an important role in the generation of seizures. Linear cross-correlation and ...

journal_title：Journal of neurophysiology

authors： Warren CP,Hu S,Stead M,Brinkmann BH,Bower MR,Worrell GA

更新日期：2010-12-01 00:00:00

abstract：:Two forms of undulatory locomotion in the lamprey (a lower vertebrate) have been described earlier: fast forward swimming (FFS) used for long distance migrations and slow backward swimming (SBS) used for escape from adverse tactile stimuli. In the present study, we describe another form of escape behavior: slow forwar...

journal_title：Journal of neurophysiology

authors： Islam SS,Zelenin PV

更新日期：2008-01-01 00:00:00

abstract：:The topographical response of a portion of an isofrequency contour in primary cat auditory cortex (AI) to a series of monaural and binaural stimuli was studied. Responses of single neurons to monaural and a matrix of binaural characteristic frequency tones, varying in average binaural level (ABL) and interaural level ...

journal_title：Journal of neurophysiology

authors： Nakamoto KT,Zhang J,Kitzes LM

更新日期：2004-01-01 00:00:00

abstract：:Experiments have been carried out on the soleus muscle and its tendon in the anesthetized cat. Measurements of isometric tension and muscle stiffness were made during contraction of whole or part of the muscle in response to stimulation of ventral root filaments. In an attempt to determine the distribution of tension ...

journal_title：Journal of neurophysiology

authors： Proske U,Morgan DL

更新日期：1984-09-01 00:00:00

abstract：:We have demonstrated that 4-aminopyridine-3-methanol (4-AP-3-MeOH), a 4-aminopyridine derivative, significantly restores axonal conduction in stretched spinal cord white-matter strips and shows no preference in restoring large and small axons. This compound is 10 times more potent when compared with 4-AP and other der...

journal_title：Journal of neurophysiology

authors： Sun W,Smith D,Fu Y,Cheng JX,Bryn S,Borgens R,Shi R

更新日期：2010-01-01 00:00:00

abstract：:1. Horizontal cells were enzymatically and mechanically dissociated from the white perch (Roccus americana) retina and voltage clamped using patch electrodes. Steady-state current-voltage (I-V) relationships of solitary horizontal cells were determined by changing the membrane potential in a rampwise fashion. 2. The I...

journal_title：Journal of neurophysiology

authors： Perlman I,Knapp AG,Dowling JE

更新日期：1988-10-01 00:00:00

abstract：:High-frequency activity produces transient depression at many synapses but also, as recently demonstrated, may accelerate the recovery from use-dependent depression. We have examined the possible consequences of this synaptic mechanism in neocortical excitatory synapses by recording simultaneously from presynaptic pyr...

journal_title：Journal of neurophysiology

authors： Galarreta M,Hestrin S

更新日期：2000-01-01 00:00:00

abstract：:Information about the position of an object that is held in both hands, such as a golf club or a tennis racquet, is transmitted to the human central nervous system from peripheral sensors in both left and right arms. How does the brain combine these two sources of information? Using a robot to move participant's passi...

journal_title：Journal of neurophysiology

authors： Wong JD,Wilson ET,Kistemaker DA,Gribble PL

更新日期：2014-03-01 00:00:00

abstract：:Through their actions in the nucleus accumbens (NAc), kappa opioid (KOP) receptors and their endogenous ligand, dynorphin, modify behaviors associated with the administration of drugs of abuse and are regulated by exposure to such drugs. Despite their demonstrated behavioral significance, the synaptic actions of KOP r...

journal_title：Journal of neurophysiology

authors： Hjelmstad GO,Fields HL

更新日期：2003-05-01 00:00:00

abstract：:Neurons constituting the pacemaker of circadian rhythms, located in the suprachiasmatic nucleus, generate spontaneous firing patterns that change across the day-night cycle. Their average spontaneous firing rate is considered an important functional marker of clock activity because it is highest during daytime and low...

journal_title：Journal of neurophysiology

authors： Pennartz CM,Bierlaagh MA,Geurtsen AM

更新日期：1997-10-01 00:00:00

abstract：:One of the fundamental principles of neuroscience is that direct electrical interactions between neurons are not possible without specialized electrical contacts, gap junctions, because the transmembrane resistance of neurons is typically much higher than the resistance of the adjacent extracellular space. However it ...

journal_title：Journal of neurophysiology

authors： Dmitriev AV,Mangel SC

更新日期：2006-03-01 00:00:00

abstract：:Red and green cones of two turtle species (Pseudemys scripta elegans and Chelydra serpentina) retina have been stained with Golgi procedures and examined by light microscopy of whole-mount tissue and by electron microscopy of serial thin sections. By light microscopy, red and green single cones appear indistinguishabl...

journal_title：Journal of neurophysiology

authors： Kolb H,Jones J

更新日期：1985-08-01 00:00:00

abstract：:Muscles paralyzed by chronic (>1 yr) spinal cord injury fatigue readily. Our aim was to evaluate whether the fatigability of paralyzed thenar muscles (n = 10) could be reduced by the repeated delivery of variable versus constant frequency pulse trains. Fatigue was induced in four ways. Intermittent supramaximal median...

journal_title：Journal of neurophysiology

authors： Thomas CK,Griffin L,Godfrey S,Ribot-Ciscar E,Butler JE

更新日期：2003-04-01 00:00:00

abstract：:1. The effects of dopamine on the slow Ca(2+)-dependent K+ current (IAHP; AHP, afterhyperpolarization) and spike frequency adaptation were studied by whole cell voltage-clamp and sharp microelectrode current-clamp recordings in rat CA1 pyramidal neurons in rat hippocampal slices. 2. Dopamine suppressed IAHP in a dose-...

journal_title：Journal of neurophysiology

authors： Pedarzani P,Storm JF

更新日期：1995-12-01 00:00:00

abstract：:With experience, an object can become behaviorally relevant and thereby quickly attract our interest when presented in a visual scene. A likely site of these learning effects is anterior inferior temporal (aIT) cortex, where neurons are thought to participate in the filtering of irrelevant information out of complex v...

journal_title：Journal of neurophysiology

authors： Jagadeesh B,Chelazzi L,Mishkin M,Desimone R

更新日期：2001-07-01 00:00:00

abstract：:Contact-evoked changes in EMG activity during human grasp. 2215 Cutaneous receptors in the digits discharge bursts of activity on contact with an object during human grasp. In this study, we investigated the contribution of this sensory activity to the responses of muscles involved in the task. Twelve subjects perform...

journal_title：Journal of neurophysiology

authors： Collins DF,Knight B,Prochazka A

更新日期：1999-05-01 00:00:00

abstract：:When a movement results in error, the nervous system amends the motor commands that generate the subsequent movement. Here we show that this adaptation depends not just on error, but also on passage of time between the two movements. We observed that subjects learned a reaching task faster, i.e., with fewer trials, wh...

journal_title：Journal of neurophysiology

authors： Huang VS,Shadmehr R

更新日期：2007-06-01 00:00:00

abstract：:1. We have developed a 16-compartment model that reproduces most of the features of the CA1 pyramidal cell electrophysiology observed experimentally. The model was constructed using seven active ionic conductances: gNa, gCa, gDR, gCT, gA, gM, and gAHP whose kinetics have been, inferred, in most cases, from the availab...

journal_title：Journal of neurophysiology

authors： Warman EN,Durand DM,Yuen GL

更新日期：1994-06-01 00:00:00

abstract：:Event-related potentials (ERPs) have provided crucial data concerning the time course of psychological processes, but the neural mechanisms producing ERP components remain poorly understood. This study continues a program of research in which we investigated the neural basis of attention-related ERP components by simu...

journal_title：Journal of neurophysiology

authors： Purcell BA,Schall JD,Woodman GF

更新日期：2013-01-01 00:00:00

abstract：:Our goal was to understand how patterns of excitation and inhibition, interacting across arrays of ganglion cells in space and time, generate the spiking output pattern for each ganglion cell type. We presented the retina with a 1-s flashed square, 600 microm on a side, and measured patterns of excitation and inhibiti...

journal_title：Journal of neurophysiology

authors： Roska B,Molnar A,Werblin FS

更新日期：2006-06-01 00:00:00

abstract：:Falls during walking are a major cause of poststroke injury, and walking faster may decrease the ability to recover following a gait perturbation. We compared gait stability between high-functioning poststroke individuals and controls and evaluated the effect of gait speed on gait stability. Ten stroke subjects and te...

journal_title：Journal of neurophysiology

authors： Krasovsky T,Lamontagne A,Feldman AG,Levin MF

更新日期：2013-01-01 00:00:00

abstract：:Many laboratories have reported the successful regeneration of neurons across damaged portions of the spinal cord. Associated improvements in hindlimb locomotor movements have been attributed to the formation of functional neuronal connections with the locomotor central pattern generator (CPG). However, regenerating a...

journal_title：Journal of neurophysiology

authors： Yakovenko S,Kowalczewski J,Prochazka A

更新日期：2007-03-01 00:00:00

abstract：:The ability of individuals to adapt locomotion to constraints associated with the complex environments normally encountered in everyday life is paramount for survival. Here, we tested the ability of 24 healthy young adults to adapt to a rightward prism shift (∼11.3°) while either walking and stepping to targets (i.e.,...

journal_title：Journal of neurophysiology

authors： Alexander MS,Flodin BW,Marigold DS

更新日期：2011-08-01 00:00:00

abstract：:Adaptation of fingertip forces to friction at the grasping surface is necessary to prevent use of inadequate or excessive grip forces. In the current study we investigated the effect of blocking tactile information from the fingertips noninvasively on the adaptation and efficiency of grip forces to surface friction du...

journal_title：Journal of neurophysiology

authors： Bilaloglu S,Lu Y,Geller D,Rizzo JR,Aluru V,Gardner EP,Raghavan P

更新日期：2016-03-01 00:00:00

abstract：:Damage to the cerebellum causes characteristic movement abnormalities but is thought to have minimal impact on somatosensory perception. Traditional clinical assessments of patients with cerebellar lesions reveal no perceptual deficits despite the fact that the cerebellum receives substantial somatosensory information...

journal_title：Journal of neurophysiology

authors： Bhanpuri NH,Okamura AM,Bastian AJ

更新日期：2012-03-01 00:00:00

abstract：:Several types of equilibrium point (EP) controllers have been proposed for the control of posture and movement. EP controllers are appealing from a computational perspective because they do not require solving the "inverse dynamic problem" (i.e., computation of the torques required to move a system along a desired tra...

journal_title：Journal of neurophysiology

authors： Kistemaker DA,Van Soest AJ,Bobbert MF

更新日期：2006-05-01 00:00:00