Abstract：
:Whether caffeine intake during pregnancy is related to intrauterine growth retardation, low birth weight, and preterm birth remains unclear. The purpose of this population-based study is to assess these associations and to evaluate the interaction between caffeine intake and smoking. The study participants (n = 7,025) were women who lived in Quebec City, Canada, and the surrounding area who gave birth between January 1989 and October 1989 to a singleton liveborn neonate. Information on gestational age at delivery, caffeine intake (coffee, tea, chocolate, and colas) during pregnancy, and several potential confounders was obtained by telephone a few weeks after delivery. Birth weight was abstracted from the birth certificate. Caffeine consumption was associated with an increased risk of intrauterine growth retardation (birth weight less than the 10th percentile for sex and gestational age). For women whose average daily caffeine consumption was 0-10, 11-150, 151-300, or > 300 mg, the adjusted odds ratios for delivering a newborn with growth retardation were 1.00, 1.28 (95% confidence interval (CI) 1.04-1.59), 1.42 (95% CI 1.07-1.87), and 1.57 (95% CI 1.05-2.33), respectively. Caffeine intake, however, was not related to preterm delivery or low birth weight. We conclude that caffeine intake during pregnancy is a risk factor for intrauterine growth retardation.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Fortier I,Marcoux S,Beaulac-Baillargeon Ldoi
10.1093/oxfordjournals.aje.a116763subject
Has Abstractpub_date
1993-05-01 00:00:00pages
931-40issue
9eissn
0002-9262issn
1476-6256journal_volume
137pub_type
杂志文章abstract：:The relation between cigarette smoking and the risk of breast cancer in women was investigated in a population-based case-control study conducted in Adelaide, Australia during 1982-1984. Cases were identified through the South Australian Central Cancer Registry, and, for each case, one age-matched control was selected...
journal_title：American journal of epidemiology
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更新日期：1989-01-01 00:00:00
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journal_title：American journal of epidemiology
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更新日期：1979-03-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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更新日期：2014-09-01 00:00:00
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更新日期：1976-06-01 00:00:00
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journal_title：American journal of epidemiology
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更新日期：1989-04-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2005-02-15 00:00:00
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更新日期：2000-02-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115169
更新日期：1989-03-01 00:00:00
abstract：:G-estimation is a flexible, semiparametric approach for estimating exposure effects in epidemiologic studies. It has several underappreciated advantages over other propensity score-based methods popular in epidemiology, which we review in this article. However, it is rarely used in practice, due to a lack of off-the-s...
journal_title：American journal of epidemiology
pub_type： 杂志文章,评审
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更新日期：2018-05-01 00:00:00
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journal_title：American journal of epidemiology
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更新日期：2006-02-01 00:00:00
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