Abstract：
:The relative contribution of menopause to the age-related increase in serum total cholesterol concentration in women is not exactly known. Cross-sectional studies suggest a considerable contribution of menopause, whereas in short-term longitudinal studies, only a small increase was observed around menopause. In a 10-year follow-up study (1979-1989), serum total cholesterol concentration and dietary intake were measured annually in 167 healthy perimenopausal women (initially aged 49-56 years) who lived in the mixed rural/industrial community of Ede, the Netherlands. The longitudinal design enabled us to study the "natural course" of serum total cholesterol concentration and the influence of dietary fat intake during and after cessation of ovulation. For data analysis, three menopausal cohorts were created based on years relative to menopause: 2 years before ("perimenopausal"), 2 years after ("early postmenopausal"), and 6 years after ("late postmenopausal"). In each cohort, the analysis was conducted on data from 4 years of follow-up. The results show that from 2 years before to 6 years after menopause, serum total cholesterol concentration increased on average by at least 1.1 mmol/liter (19%). Thereafter, only a minor increase was observed. The rise was significantly lower in women who increased their intake of polyunsaturated fatty acids as compared with women who reduced their intake during that period. It is concluded that cessation of ovulation appears to be associated with a major increase of 19% in serum total cholesterol concentration during an 8-year period around menopause. This increase may be reduced by increasing the intake of polyunsaturated fatty acids.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
van Beresteijn EC,Korevaar JC,Huijbregts PC,Schouten EG,Burema J,Kok FJdoi
10.1093/oxfordjournals.aje.a116686subject
Has Abstractpub_date
1993-02-15 00:00:00pages
383-92issue
4eissn
0002-9262issn
1476-6256journal_volume
137pub_type
杂志文章abstract：:Population-based and proportional odds ratios for various cancers, based on incidence data from 1974-1977 and mortality data from 1965-1975 for western Washington State, were calculated in relation to three measures of exposure to asbestos in community water supplies. Six odds ratios were calculated for each neoplasm ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113415
更新日期：1982-08-01 00:00:00
abstract：:Ambient levels of particulate matter have been linked to cardiovascular disease. The mechanisms mediating these associations are poorly understood. One candidate mechanism is inflammation. Using data from the Multi-Ethnic Study of Atherosclerosis (2000-2002), the authors investigated the relation between exposure to p...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwj186
更新日期：2006-09-01 00:00:00
abstract：:Rhinovirus infections in Seattle families with schoolchildren (1975-1979) and in selected outpatients were revealed by virus shedding or antibody rise. These observations extend those in the Seattle Virus Watch (1965-1969). Analysis of rhinovirus serotype prevalence again revealed certain "common" persisting serotypes...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114166
更新日期：1985-11-01 00:00:00
abstract：:We determined measurement properties of the Sedentary Time and Activity Reporting Questionnaire (STAR-Q), which was designed to estimate past-month activity energy expenditure (AEE). STAR-Q validity and reliability were assessed in 102 adults in Alberta, Canada (2009-2011), who completed 14-day doubly labeled water (D...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwu150
更新日期：2014-08-15 00:00:00
abstract：:As the population ages, the burden of disease from cognitive decline and dementing illness is rising. In the absence of treatments to reverse cognitive decline, prevention is a public health priority. Physical fitness and physical activity have emerged as prevention targets based on evidence of "neuroprotective" benef...
journal_title：American journal of epidemiology
pub_type： 评论,杂志文章
doi：10.1093/aje/kww029
更新日期：2016-06-15 00:00:00
abstract：:It has been suggested that future research into the adverse effects of binge drinking in pregnancy should take into account the time of binge drinking, and a method has been proposed. In a representative sample of 1,311 pregnant Danish women in 2000, the agreement between two different measures of binge drinking durin...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwh095
更新日期：2004-04-15 00:00:00
abstract：:A recent article by Little et al. (Am J Epidemiol 1994;140:544-54) reported that infants in Seattle, Washington, who were breastfed by mothers who smoked gained more weight than either infants who were breastfed by mothers who did not smoke or infants who were bottle-fed by mothers who smoked. In this study, the autho...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009423
更新日期：1998-01-15 00:00:00
abstract：:Many epidemiologists have agreed that a refined estimate of the incubation period of severe acute respiratory syndrome (SARS) would need a sample size of about 200 cases and appropriate statistical methods enabling the inclusion of cases with defined periods of exposure. However, no such studies have been reported so ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwj034
更新日期：2006-02-01 00:00:00
abstract：:Ambient air pollution and temperature have been linked with cardiovascular morbidity and mortality. Metabolic syndrome and its components-abdominal obesity, elevated fasting blood glucose concentration, low high-density lipoprotein cholesterol concentration, hypertension, and hypertriglyceridemia-predict cardiovascula...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kww157
更新日期：2017-01-01 00:00:00
abstract：:Circumstances in which both randomized controlled trial and observational study data are available provide an important opportunity to identify biases and improve study design and analysis procedures. In addition, joint analyses of data from the two sources can extend clinical trial findings. The US Women's Health Ini...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwj079
更新日期：2006-04-01 00:00:00
abstract：:Although data on the prevalence of injection drug use are an essential prerequisite for estimating the number of individuals infected with the human immunodeficiency virus (HIV), there have been few attempts to utilize statistical methods of population estimation based on multiple data sources. Data on 3,670 cases (2,...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116843
更新日期：1993-08-01 00:00:00
abstract：:The relation between death from acute myocardial infarction and the level of magnesium in drinking water was examined using mortality registers and a case-control design. The study area comprised 17 municipalities in the southern part of Sweden that have different magnesium levels in the drinking water. Cases were men...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a008765
更新日期：1996-03-01 00:00:00
abstract：:Differences in hygienic habits and base-line secretory immunoglobulin (Ig) A which might have contributed to the prevalence of skin infections and/or absence of increased serum IgA values were sought in patients with poststreptococcal acute glomerulonephritis (nephritis) in contrast to patients with acute rheumatic fe...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113382
更新日期：1982-06-01 00:00:00
abstract：:The use of propensity scores to adjust for measured confounding factors has become increasingly popular in cohort studies. However, their use in case-control and case-cohort studies has received little attention. The authors present some theory on the estimation and use of propensity scores in case-control and case-co...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwm069
更新日期：2007-08-01 00:00:00
abstract：:The authors present analyses of data from three independent clinical series and controls indicating an association between working in occupations with probable medium to high exposure to extremely low frequency (< 300 Hz) electromagnetic fields and sporadic Alzheimer's disease. Case-control analyses were carried out u...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117669
更新日期：1995-09-01 00:00:00
abstract：:The identity of the etiologic agent that caused the 1981 epidemic of toxic oil syndrome in Spain has not been established, and toxicologic study of oil specimens from the outbreak has been hampered by uncertainty about which oils were actually capable of causing illness. To identify chemical characteristics associated...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114914
更新日期：1988-06-01 00:00:00
abstract：:Childhood blood pressure (BP) is a strong predictor of later risk of cardiovascular disease. However, few studies have assessed dynamic BP trajectories throughout the early-life period. We investigated the relationship between early-life factors and systolic BP (SBP) from infancy to adolescence using linear spline mix...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwz181
更新日期：2019-11-01 00:00:00
abstract：:The continued elimination of measles requires accurate assessment of its epidemiology and a critical evaluation of how its incidence is changing with time. National surveillance of measles in the United States between 2001 and 2011 provides data on the number of measles introductions and the size of the resulting tran...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwu068
更新日期：2014-06-01 00:00:00
abstract：:As economic development increases, puberty occurs at younger ages, and this could contribute to an increase in the incidence of cardiovascular diseases and hormone-related cancers. The factors that determine pubertal timing are poorly understood. The growth axis that is active during puberty is active in the first 6 m...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwr028
更新日期：2011-06-15 00:00:00
abstract：:Recent studies suggest that no distinct glycemic threshold consistently differentiates individuals with or without retinopathy. The authors sought to determine whether the same was true for other microvascular complications. They studied 5,094 participants with fasting plasma glucose values and concurrent microvascula...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwp076
更新日期：2009-06-15 00:00:00
abstract：:Approximately 40,000 blood samples drawn in 1968-1972 by the Social Insurance Institution's mobile clinic in Finland have been stored. Linking cancer incidence data obtained from the Finnish Cancer Registry with this material yielded 32 cases of cervical cancer diagnosed after drawing of the blood sample. These 32 ind...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116656
更新日期：1993-01-15 00:00:00
abstract：:Cigarette smoking during pregnancy is an important, avoidable factor associated with low birth weight. Maternal age is also associated with variations in birth weight. Using birth certificate data from all 347,650 singleton births for which maternal age and birth weight were recorded during 1984-1988 in Washington Sta...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116940
更新日期：1994-05-15 00:00:00
abstract：:Production of synthetic rubber involves exposure to several potentially harmful chemicals. The authors carried out a systematic review and meta-analysis of cohort studies of workers in the rubber-producing industry. Data were obtained from computerized literature searches of several databases from their inception thro...
journal_title：American journal of epidemiology
pub_type： 杂志文章,meta分析
doi：10.1093/aje/kwj252
更新日期：2006-09-01 00:00:00
abstract：:Female breast cancer patients who had participated in a case-control study conducted during 1973-1975 were followed up, using record linkage to the Statistics Canada mortality data base, to the end of 1980. A number of variables recorded for the case-control study, in particular body weight and daily intake of dietary...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114305
更新日期：1986-05-01 00:00:00
abstract：:Benign breast disease is associated with increased risk of breast cancer. To further clarify whether there is a genetic link between benign and malignant breast lesions, the authors identified 14,648 first-degree female relatives of 8,807 patients in whom breast cancer was diagnosed at <50 years of age by using Danish...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwn133
更新日期：2008-08-01 00:00:00
abstract：:The objective of this study was to examine how the consistency of self-reported exposure to dust or gas, asbestos, and quartz varied between subjects with and those without respiratory symptoms and asthma in a Norwegian community sample () in 1987-1988. Exposure characterization obtained in a structured work history i...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/154.5.477
更新日期：2001-09-01 00:00:00
abstract：:The patterns of change in blood lipids, diastolic blood pressure, body mass index, smoking and drinking behaviors, and exercise were examined in an ongoing longitudinal study from 1991 to 1995 of 150 middle-aged Melbourne, Australia, women as they passed through menopause. Changes in risk factors over time were examin...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a010246
更新日期：2000-03-15 00:00:00
abstract：:Evidence from animal and cell models suggests that pesticides cause a neurodegenerative process leading to Parkinson's disease (PD). Human data are insufficient to support this claim for any specific pesticide, largely because of challenges in exposure assessment. The authors developed and validated an exposure assess...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwp006
更新日期：2009-04-15 00:00:00
abstract：:To evaluate strategies used to select cases and controls and how reported odds ratios are interpreted, the authors examined 150 case-control studies published in leading general medicine, epidemiology, and clinical specialist journals from 2001 to 2007. Most of the studies (125/150; 83%) were based on incident cases; ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwn217
更新日期：2008-11-01 00:00:00
abstract：:We investigated the possible association between body mass index (BMI; weight (kg)/height (m)(2)) and hospitalization or treatment for acute infection in a prospective cohort study. We linked 75,001 women enrolled in the Danish National Birth Cohort from 1996 to 2002, who had information on BMI and a broad range of co...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwv300
更新日期：2016-06-01 00:00:00
