Abstract:
:The authors investigated whether red blood cell distribution width (RDW) was associated with the development of cardiovascular disease (CVD) events and mortality in a community cohort in Taiwan. The influence of anemia on the association was also assessed. RDW levels were measured in 3,226 participants aged 35 years or older who reported no CVD or cancer at baseline in 1990. During a median follow-up period of 15.9 years (1990-2007), 358 participants experienced stroke and/or coronary heart disease, and 810 participants died. The multivariate-adjusted hazard ratio for subjects in the highest RDW quartile as compared with the lowest quartile was 1.46 for both all-cause mortality (95% confidence interval: 1.17, 1.81) and non-CVD mortality (95% confidence interval: 1.13, 1.88) (P for trend < 0.01 for both) but was not significant for CVD morbidity and mortality. Further analyses showed that in comparison with participants with low RDW and no anemia, persons with high RDW but no anemia had elevated risks of all-cause mortality and non-CVD mortality. The authors conclude that elevated RDW values are associated with increased risk of mortality but not the development of CVD in the general population. RDW may precede anemia in predicting the risk of non-CVD death.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Chen PC,Sung FC,Chien KL,Hsu HC,Su TC,Lee YTdoi
10.1093/aje/kwp360subject
Has Abstractpub_date
2010-01-15 00:00:00pages
214-20issue
2eissn
0002-9262issn
1476-6256pii
kwp360journal_volume
171pub_type
杂志文章abstract::In this study, we assessed the association of chronic medical conditions and multimorbidity with perceived stress among community-dwelling adults in 44 low- and middle-income countries. Data from the World Health Survey (2002-2004), including 229,293 adults, were analyzed. A perceived stress score (range, 0 (lowest st...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwx159
更新日期:2017-10-15 00:00:00
abstract::There is accumulating evidence suggesting that children may drive the spread of influenza epidemics. The objective of this study was to quantify the lead time by age using laboratory-confirmed cases of influenza A for the 1995/1996-2005/2006 seasons from Canadian communities and laboratory-confirmed hospital admission...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwr037
更新日期:2011-07-01 00:00:00
abstract::The authors describe an approach to the analysis of case-control studies in which the exposure variables are continuous, i.e., quantitative variables, and one wishes neither to categorize levels of the exposure variable nor to assume a log-linear relation between level of exposure and disease risk. A dose-response ass...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a008970
更新日期:1996-09-15 00:00:00
abstract::The preterm delivery rate in North Carolina is consistently higher than the national average. However, recent reports suggest that singleton preterm delivery rates for non-Hispanic Whites are increasing while those for non-Hispanic African Americans are decreasing. To study this pattern further, the authors examined d...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwh011
更新日期:2004-01-01 00:00:00
abstract::The World Health Organization (Geneva, Switzerland) and the National Heart, Lung, and Blood Institute (Bethesda, Maryland) have developed standard categories of body mass index (BMI) (calculated as weight (kg)/height (m)(2)) of less than 18.5 (underweight), 18.5-24.9 (normal weight), 25.0-29.9 (overweight), and 30.0 o...
journal_title:American journal of epidemiology
pub_type: 杂志文章,meta分析
doi:10.1093/aje/kwu111
更新日期:2014-08-01 00:00:00
abstract::The relation of blood pressure, serum cholesterol, plasma fibrinogen, and coagulation factor VIIc with skinfold thickness at four sites (forearm, triceps, suprailiac, and subscapular) was examined in 2,948 white participants in the Northwick Park Heart Study. When considered separately, all four skinfolds were signifi...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114665
更新日期:1987-07-01 00:00:00
abstract::The etiology of acute diarrhea (less than or equal to 3 days duration) and persistent diarrhea (greater than or equal to 14 days duration) was determined in Cambodian children under age 5 years in a refugee camp on the Thai-Cambodian border between May and October 1989; potential risk factors associated with persisten...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a116321
更新日期:1992-03-01 00:00:00
abstract::Sequences of treatments that adapt to a patient's changing condition over time are often needed for the management of chronic diseases. An adaptive treatment strategy (ATS) consists of personalized treatment rules to be applied through the course of a disease that input the patient's characteristics at the time of dec...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwz272
更新日期:2020-05-05 00:00:00
abstract::The performance of three approximate confidence limit methods for the odds ratio, R, is studied at the 95% level in the unconditional sample space. There are: the method proposed by Cornfield (Proceedings of the 3rd Berkeley Symposium 1956;4:135-48), the logit method with 1/2 corrections first considered by Woolf (Ann...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113323
更新日期:1982-03-01 00:00:00
abstract::Earlier epidemiologic studies have suggested an inverse association between non-Hodgkin's lymphoma and exposure to histamine(2) (H(2)) blockers, nonsteroidal anti-inflammatory drugs, cholesterol-lowering drugs, and antibiotics. Data from the PHARMO database were used to conduct a nested, population-based case-control ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwg004
更新日期:2003-03-15 00:00:00
abstract::Observational longitudinal research is particularly useful for assessing etiology and prognosis and for providing evidence for clinical decision making. However, there are no structured reporting requirements for studies of this design to assist authors, editors, and readers. The authors developed and tested a checkli...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwi042
更新日期:2005-02-01 00:00:00
abstract::In Australia, as in many industrialized countries, the past 50 years have been marked by increasing female labor-force participation. It is popularly speculated that this might impose a mental-health burden on women and their children. This analysis aimed to examine the associations between household labor-force parti...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwaa138
更新日期:2020-12-01 00:00:00
abstract::The effects of occupational 60 Hz magnetic field and ambient light exposures on the pineal hormone, melatonin, were studied in 142 male electric utility workers in Colorado, 1995-1996. Melatonin was assessed by radioimmunoassay of its metabolite, 6-hydroxymelatonin sulfate (6-OHMS), in post-work shift urine samples. P...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009914
更新日期:1999-07-01 00:00:00
abstract::This study involved direct observation of the differences in utilization of medical care by smokers, nonsmokers, and former smokers. A household interview survey conducted in 1970-1971 obtained detailed information about the smoking patterns of 2,582 adult members of the Northwest Kaiser Permanente health maintenance ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114187
更新日期:1985-12-01 00:00:00
abstract::Genetic epidemiology represents a hybrid of epidemiologic designs and statistical models that explicitly consider both genetic and environmental risk factors for disease. It is a relatively new field in public health; the term was first coined only 35 years ago. In this short time, the field has been through a major e...
journal_title:American journal of epidemiology
pub_type: 历史文章,杂志文章
doi:10.1093/aje/kww001
更新日期:2016-03-01 00:00:00
abstract::Medical devices play a vital role in diagnosing, treating, and preventing diseases and are an integral part of the health-care system. Many devices, including implantable medical devices, enter the market through a regulatory pathway that was not designed to assure safety and effectiveness. Several recent studies and ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwu206
更新日期:2014-11-01 00:00:00
abstract::How can the "strengths" of risk factors, in the sense of how well they discriminate cases from controls, be compared when they are measured on different scales such as continuous, binary, and integer? Given that risk estimates take into account other fitted and design-related factors-and that is how risk gradients are...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwv193
更新日期:2015-11-15 00:00:00
abstract::Populations of Mexican descent have high occurrences of neural tube defects (NTDs). A recent study suggested that folic acid supplements may not protect these populations from NTDs. In a case-control study, the authors investigated the role of folic acid and dietary folate intake in NTD risk among Mexican Americans li...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/152.11.1017
更新日期:2000-12-01 00:00:00
abstract::Since June 1982, the Wisconsin Chronic Renal Disease Program has provided reimbursement for hepatitis B virus vaccine and pre- and postvaccine serologic testing for patients and staff in all Wisconsin renal dialysis centers. Between July 1, 1982 and June 30, 1984, 444 dialysis patients in 22 renal dialysis centers and...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114858
更新日期:1988-04-01 00:00:00
abstract::The authors present analyses of data from three independent clinical series and controls indicating an association between working in occupations with probable medium to high exposure to extremely low frequency (< 300 Hz) electromagnetic fields and sporadic Alzheimer's disease. Case-control analyses were carried out u...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a117669
更新日期:1995-09-01 00:00:00
abstract::The relation between anesthetic gas exposure and spontaneous abortion remains unresolved. We examined the effect of nitrous oxide on spontaneous abortion among female dental assistants. Questionnaires were sent to 7,000 dental assistants aged 18-39 years who were registered in California in 1987; 4,856 (69%) responded...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a117468
更新日期:1995-03-15 00:00:00
abstract::To investigate the validity of outdoor particulate matter with a 50% cutoff diameter of 10-microm (PM10) concentrations as a measure of exposure in time series studies, the association between personal and outdoor concentrations, within subjects, over time was investigated. Repeated measurements of personal, indoor, a...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009485
更新日期:1998-03-15 00:00:00
abstract::The authors investigated the association between age at menarche and risk of type 2 diabetes mellitus (T2DM) among 101,415 women from the Nurses' Health Study (NHS) aged 34-59 years (1980-2006) and 100,547 women from Nurses' Health Study II (NHS II) aged 26-46 years (1991-2005). During 2,430,274 and 1,373,875 person-y...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwp372
更新日期:2010-02-01 00:00:00
abstract::This population-based case-referent study investigated the lung cancer risk associated with occupational exposure to asbestos, focusing on dose-response relations and the interaction with tobacco smoking. Incident cases of lung cancer among males aged 40-75 years in Stockholm County, Sweden, were identified from 1985 ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/155.11.1016
更新日期:2002-06-01 00:00:00
abstract::A new viral agent, isolated from the serum of an infectious hepatitis patient and designated as Agent II-B, was extensively studied in in vitro and in vivo systems. Agent II-B multiplied well in primary and serial animal cell cultures and in embryonated hen's eggs. Quantal and quantitative infectivity assays were perf...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a112715
更新日期:1979-05-01 00:00:00
abstract::Childhood blood pressure (BP) is a strong predictor of later risk of cardiovascular disease. However, few studies have assessed dynamic BP trajectories throughout the early-life period. We investigated the relationship between early-life factors and systolic BP (SBP) from infancy to adolescence using linear spline mix...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwz181
更新日期:2019-11-01 00:00:00
abstract::The authors have conducted an analysis to validate a computer model that uses age-specific human immunodeficiency virus (HIV) prevalence data to estimate age-specific HIV incidence rates. Data for the analysis are from a cohort study of volunteer male workers in Bujumbura, the capital city of Burundi. Testing for HIV ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a008916
更新日期:1996-08-01 00:00:00
abstract::Although missing outcome data are an important problem in randomized trials and observational studies, methods to address this issue can be difficult to apply. Using simulated data, the authors compared 3 methods to handle missing outcome data: 1) complete case analysis; 2) single imputation; and 3) multiple imputatio...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwr302
更新日期:2012-02-01 00:00:00
abstract::Evidence on dietary risk factors for ovarian cancer is inconsistent, but some studies have suggested positive associations with dietary fat, lactose, and cholesterol and negative associations with green and yellow vegetable intake. By using information from the Iowa Women's Health Study, the authors investigated the a...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009723
更新日期:1999-01-01 00:00:00
abstract::Experiences of discrimination are associated with increased risk of adverse health outcomes; however, it is unknown whether discrimination is related to incident type 2 diabetes mellitus (diabetes). We investigated the associations of major experiences of discrimination (unfair treatment in 6 situations) and everyday ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwx047
更新日期:2017-08-15 00:00:00