Abstract:
:Genetic epidemiology represents a hybrid of epidemiologic designs and statistical models that explicitly consider both genetic and environmental risk factors for disease. It is a relatively new field in public health; the term was first coined only 35 years ago. In this short time, the field has been through a major evolution, changing from a field driven by theory, without the technology for genetic measurement or computational capacity to apply much of the designs and methods developed, to a field driven by rapidly expanding technology in genomic measurement and computational analyses while epidemiologic theory struggles to keep up. In this commentary, we describe 4 different eras of genetic epidemiology, spanning this evolution from theory to technology, what we have learned, what we have added to the broader field of public health, and what remains to be done.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Fallin MD,Duggal P,Beaty THdoi
10.1093/aje/kww001subject
Has Abstractpub_date
2016-03-01 00:00:00pages
387-93issue
5eissn
0002-9262issn
1476-6256pii
kww001journal_volume
183pub_type
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