Abstract:
:The relation between cigarette smoking and the risk of breast cancer in women was investigated in a population-based case-control study conducted in Adelaide, Australia during 1982-1984. Cases were identified through the South Australian Central Cancer Registry, and, for each case, one age-matched control was selected from the electoral register; in all, 451 case-control pairs were enrolled. Overall, no clear association was found between ever or current smoking and breast cancer risk. In a subgroup analysis, premenopausal ex-smokers were observed to have an increased risk (estimated odds ratio = 2.3). The absence of a protective effect of cigarette smoking on breast cancer risk may reflect the relatively weak estrogen dependence of breast cancer, or the nature of its hormone dependence.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Rohan TE,Baron JAdoi
10.1093/oxfordjournals.aje.a115122subject
Has Abstractpub_date
1989-01-01 00:00:00pages
36-42issue
1eissn
0002-9262issn
1476-6256journal_volume
129pub_type
杂志文章abstract::The Icelandic study of melanoma trends by Héry et al. in this issue of the Journal (Am J Epidemiol. 2010;172(7):762-767) is a fascinating analysis of an ecologic association. The authors noted a sharp increase in melanoma incidence that appeared to lag a few years behind the increased prevalence of sunbeds in Iceland....
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abstract::Exposure to cadmium confers increased cardiovascular risk. Tobacco smoke contains cadmium, which, hypothetically, may mediate parts of the tobacco-associated risk of developing atherosclerotic plaques. Baseline data from the Swedish Malmö Diet and Cancer cohort (1991-1996) were used to test this hypothesis. Mediation ...
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abstract::The structured life course modeling approach (SLCMA) is a theory-driven analytic method that empirically compares multiple prespecified life course hypotheses characterizing time-dependent exposure-outcome relationships to determine which theory best fits the observed data. In this study, we performed simulations and ...
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