Abstract：
:Fifty-eight children with Reye's syndrome (RS) confirmed by liver biopsy were treated at the University of Cincinnati between 1963 and 1974. Cases were clustered in the winter and spring with the peak in February and March. These coincided with the occurrence of influenza and, numerically, were associated more closely with influenza B than with influenza A. Six of the 58 cases were associated with chickenpox. Twenty-six children with RS were seen from 1963 to 1971, before the beginning of a systematic epidemiologic and virologic study. Viral infection was documented in either the patient or a contact in only 19% of those studied. Between 1971 and 1973, after the study was initiated, 16 cases of RS were diagnosed and viral infection was confirmed in 56% of these. In 1974, an epidemic of RS occurred during an influenza B epidemic and viral infection was found in either the patient or a contact in 81% of 16 cases. This study demonstrates that an association with viral infection can be proven in the majority of cases of RS when an intensive investigation is undertaken. During this study no significant environmental toxic exposures could be idenified. Most children had taken aspirin and other medications, and seven children had a history of excessive aspirin ingestion.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Linnemann CC Jr,Shea L,Partin JC,Schubert WK,Schiff GMdoi
10.1093/oxfordjournals.aje.a112123subject
Has Abstractpub_date
1975-06-01 00:00:00pages
517-26issue
6eissn
0002-9262issn
1476-6256journal_volume
101pub_type
杂志文章abstract：:A retrospective cohort study of workers exposed to phenoxy herbicides, chlorophenols, and contaminants (2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other polychlorinated dioxins and furans) has been conducted in a chemical factory in the Netherlands. Male workers exposed to phenoxy herbicides or chlorophenols showe...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009543
更新日期：1998-05-01 00:00:00
abstract：:The association between four and two-thirds years incidence of coronary heart disease (CHD) and serum cholesterol, blood pressure (BP), height, body weight, cigarette smoking and physical activity at work and at leisure, was studied in 14,816 Oslo men, aged 40-49 years at entry to the study and free of cardiovascular ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112965
更新日期：1980-07-01 00:00:00
abstract：:Women with higher parity have a lower risk of ovarian cancer possibly because of pregnancy hormones, but the specific effect of different pregnancy hormones on ovarian cancer risk is not clear. Some clarification might be gained by considering situations where hormone levels vary between pregnancies. Study participant...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwp185
更新日期：2009-09-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章,多中心研究
doi：10.1093/aje/kwi295
更新日期：2005-11-01 00:00:00
abstract：:Stroke mortality is reported to be greater in blacks than in whites, but stroke incidence data for blacks and Hispanics are sparse. The aim of this study was to determine and compare stroke incidence rates among whites, blacks, and Hispanics living in the same urban community. A population-based incidence study was co...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009445
更新日期：1998-02-01 00:00:00
abstract：:Risk factors for neonatal seizures were evaluated in 116,048 infants born between 1992 and 1994 to residents of Harris County, Texas; 207 of these infants were diagnosed with clinical neonatal seizures. Information was obtained from the infant's birth certificate to assess the relation between seizures and birth weigh...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/154.1.14
更新日期：2001-07-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwy023
更新日期：2018-06-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwu011
更新日期：2014-05-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章,多中心研究
doi：10.1093/oxfordjournals.aje.a009975
更新日期：1999-07-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章,meta分析
doi：10.1093/aje/kwu111
更新日期：2014-08-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113021
更新日期：1980-10-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章,meta分析
doi：10.1093/aje/kwt170
更新日期：2013-09-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwi337
更新日期：2005-12-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112298
更新日期：1976-09-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/153.6.610
更新日期：2001-03-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/155.2.159
更新日期：2002-01-15 00:00:00
abstract：:The relation between cigarette smoking and the risk of breast cancer in women was investigated in a population-based case-control study conducted in Adelaide, Australia during 1982-1984. Cases were identified through the South Australian Central Cancer Registry, and, for each case, one age-matched control was selected...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115122
更新日期：1989-01-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwx344
更新日期：2018-05-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a010129
更新日期：2000-05-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwi308
更新日期：2005-11-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117632
更新日期：1995-08-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009048
更新日期：1997-05-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114058
更新日期：1985-06-01 00:00:00
abstract：:Contemporary searches for new risk factors frequently involve genome-wide explorations of very large numbers of candidate risk variants. Given that diseases can often be classified into subtypes that possess evidence of etiologic heterogeneity, the question arises as to whether or not a search for new risk factors wou...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kws128
更新日期：2012-09-15 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwn042
更新日期：2008-05-15 00:00:00
abstract：:This paper introduces the projection methods for describing and testing the differences between pairs of continuous distributions. These methods include the projection plot, the projection spline, and the iter-1 test. The projection plot displays the difference between corresponding quantiles against the average of th...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009234
更新日期：1997-12-15 00:00:00
abstract：:Preliminary evidence suggests that daytime sleepiness may predate clinical diagnosis of Parkinson disease. The authors examined daytime napping and nighttime sleeping durations, reported in 1996-1997 by 220,934 US NIH-AARP Diet and Health Study participants, in relation to Parkinson disease diagnoses at 3 clinical sta...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwq478
更新日期：2011-05-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/154.9.787
更新日期：2001-11-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：2005-10-15 00:00:00
abstract：:Logistic regression was used to estimate the "relative" risk of basal and squamous skin cancer for such factors as cumulative lifetime solar exposure, age, complexion, and tannability. In previous reports, a subject's exposure was estimated indirectly, by latitude, or by the number of sun days in a subject's habitat. ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112638
更新日期：1978-11-01 00:00:00
