Comparison of the Western immunoblot assay and a glycoprotein G enzyme immunoassay for detection of serum antibodies to herpes simplex virus type 2 in patients with AIDS.

Abstract:

:Herpes simplex virus type 2 (HSV-2) seroprevalence in 68 patients with AIDS was 77% by Western blot (immunoblot) and 44% by glycoprotein G-2 immunoassay. Each of 16 patients with culture-proven HSV-2 infection was positive by Western blot versus 8 by glycoprotein G-2 immunoassay. No differences in age, race, duration of AIDS, acyclovir usage, or HSV-1 seroprevalence were found to explain differences in sensitivity.

journal_name

J Clin Microbiol

authors

Safrin S,Arvin A,Mills J,Ashley R

doi

10.1128/JCM.30.5.1312-1314.1992

subject

Has Abstract

pub_date

1992-05-01 00:00:00

pages

1312-4

issue

5

eissn

0095-1137

issn

1098-660X

journal_volume

30

pub_type

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