Abstract:
:Magnesium sulfate is used for seizure prophylaxis in patients with preeclampsia. It also has significant effects on calcium metabolism and could, therefore, alter the pressor response to calcium-dependent vasoconstrictors. The present in vivo rat study examined the effect of magnesium sulfate to alter the pressor response to norepinephrine (NE) and angiotensin II (A II). Magnesium doses were chosen to approximate those used in treating preeclampsia. NE resulted in a significant rise in mean arterial pressure (delta MAP, 46 +/- 3.7 mmHg; p < 0.001). A II also resulted in a significant rise in MAP (delta MAP, 23 +/- 3.6 mmHg, p < 0.02). Magnesium sulfate alone had no significant effect on MAP but attenuated the pressor response to both NE (delta MAP, 16 +/- 1.5 mmHg) and A II (delta MAP, 12 +/- 2.5 mmHg). After discontinuation of the magnesium sulfate infusion, the control pressor responses to NE and A II were again seen (delta MAP, 39 +/- 3.5 mmHg and delta MAP, 28 +/- 4.2 mmHg, respectively). Although magnesium sulfate is not a primary antihypertensive agent, it may have effects on blood pressure by attenuating the actions of circulating vasoconstrictors.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Aisenbrey GA,Corwin E,Catanzarite Vdoi
10.1055/s-2007-999292subject
Has Abstractpub_date
1992-09-01 00:00:00pages
477-80issue
5-6eissn
0735-1631issn
1098-8785journal_volume
9pub_type
杂志文章abstract::Four cases of transient polyhydramnios are reviewed. It is proposed that by taking note of changes in amniotic fluid volume, one can more accurately assess a fetal-maternal unit that is affected by a number of specific disease processes. ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999656
更新日期:1988-01-01 00:00:00
abstract::We present a rare occurrence of an early-onset extensive cystic hygroma colli with intralesional hemorrhage and a favorable outcome. A 23-year-old primigravida woman was referred for management of a left isolated extensive cystic hygroma colli at 22 weeks' gestation. Amniocentesis revealed a 46, XY karyotype. Ultrasou...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994077
更新日期:1998-01-01 00:00:00
abstract::Although various authors recommend screening for hypoglycemia in large for gestational age (LGA) and small for gestational age (SGA) newborns, the frequency of hypoglycemia in these infants, using a recent definition of hypoglycemia, and the proper duration of screening are not documented. We determined chromogen test...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994649
更新日期:1993-03-01 00:00:00
abstract::For maternal metabolism, pregnancy ends not with delivery, but with weaning. In several recent epidemiological studies, authors have reported an association between duration of breast-feeding and reduced maternal risk of metabolic disease. These findings parallel data from animal models showing favorable changes in me...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0028-1103034
更新日期:2009-01-01 00:00:00
abstract::A recent report has noted an association between Helicobacter pylori and hyperemesis gravidarum. We present two cases in which first-trimester patients with severe hyperemesis gravidarum requiring intravenous fluid replacement were placed on oral erythromycin therapy for other nonrelated conditions. Surprisingly, mark...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994055
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE: This study aimed to determine whether outcomes differed between infants enrolled in the PREMOD2 trial and those otherwise eligible but not enrolled, and whether the use of waiver effected these differences. STUDY DESIGN: The multicenter PREMOD2 (PREmature infants receiving Milking Or Delayed cord clamping) ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1719184
更新日期:2020-11-03 00:00:00
abstract::Elevated serum transaminase levels can have many different etiologies, especially in the pregnant patient. Hypoxic hepatitis is a distinct syndrome caused by decreased hepatic blood flow that presents with a marked, but transient, increase in liver enzymes. A 28-year-old woman, gravida 3, para 2 with history of gastri...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0028-1085065
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:The management of breech presentation may improve perinatal outcomes. The aim of this study was to synthesize and compare published evidence of four national guidelines on breech presentation. STUDY DESIGN:A descriptive review of four recently published national guidelines on breech presentation and external...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1692391
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:The aim of the study is to determine if umbilical cord serum concentrations of interleukin-6 (IL-6), C-reactive protein (CRP), and myeloperoxidase (MPO), in pregnancies at risk for preterm birth (PTB), are associated with neonatal morbidities and/or altered neurodevelopmental outcomes in the children. STUDY ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0033-1359723
更新日期:2014-09-01 00:00:00
abstract::We present an unusual case in which sonographic assessment at 33 weeks' gestation, 5 weeks following a normal fetal anatomical survey and biometry, demonstrated a large, irregular-shaped, echogenic, suprasellar midline intracranial mass occupying the anterior and middle fossas. Associated severe obstructive hydrocepha...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994064
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:To describe the trend and factors associated with the autopsy over the past decade at a level III neonatal intensive care unit (NICU) where all patients are presented with an option. STUDY DESIGN:Retrospective study of the autopsy in a cohort of infants who died in the NICU from January 1, 2001, to December...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0032-1332798
更新日期:2013-10-01 00:00:00
abstract::In 18 women with gestational diabetes the variables of an oral glucose tolerance test (fasting and 2-hour blood glucose values and area under the blood glucose curve) performed in the last trimester of pregnancy correlated significantly with the urinary C-peptide excretion during the first 12 hours of the life (r = 0....
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999674
更新日期:1988-04-01 00:00:00
abstract:OBJECTIVE:The objective of this article is to evaluate the implementation and acceptability of a universal cervical length (CL) screening program for prediction and prevention of preterm birth (PTB). STUDY DESIGN:We performed a prospective observational study to evaluate the implementation and acceptability of a unive...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1371710
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of pretreatment with obestatin (OB), an endogenous hormone also found in mother's milk, in experimental necrotizing enterocolitis (NEC). STUDY DESIGN:Pups were randomized into four groups: control, OB-control, NEC, and OB-NEC. NEC was induced by asphyxia and hypothermia in the NEC a...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1676491
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:The aim of this article is to evaluate the accuracy, precision, and safety of transcutaneous carbon dioxide tension (TcPCO2) monitoring at different electrode temperatures in preterm infants in the early postnatal period. STUDY DESIGN:A total of 26 neonates with a median birth weight of 974 g (432-1,694 g) a...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0033-1352485
更新日期:2014-05-01 00:00:00
abstract::Classically, genetically decreased bilirubin conjugation and/or hemolysis account for the mechanisms contributing to neonatal hyperbilirubinemia associated with glucose-6-phosphate dehydrogenase (G6PD) deficiency. However, these mechanisms are not involved in most cases of this hyperbilirubinemia. Additional plausible...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1585465
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:This study aims to determine risk factors for rehospitalization in extremely premature infants. STUDY DESIGN:A retrospective cohort study of 157 infants born < 29 weeks' gestational age assessing risk factors for rehospitalization through 2 years of life. RESULTS:Multivariable logistic regression showed tha...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1555123
更新日期:2016-01-01 00:00:00
abstract::We report the case of a term male infant with severe persistent pulmonary hypertension of the newborn, who developed massive neutrophilia of unknown etiology. An extensive evaluation failed to disclose an obvious cause for his neutrophilia. A bone marrow aspirate was performed and was consistent with a leukemoid react...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2003-45288
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:We investigated the association between gestational weight gain (GWG) and postpartum depression (PPD) in women with class III obesity. STUDY DESIGN:This is a retrospective cohort of women with body mass index (BMI) ≥ 40 kg/m2 at entry to care, first prenatal visit ≤14 weeks gestation, with singleton, nonanom...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1693989
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To identify single nucleotide polymorphisms (SNPs) associated with clinical chorioamnionitis among preterm infants. STUDY DESIGN:We reanalyzed a genome-wide association study (GWAS) from preterm newborns at less than 30 weeks' gestation. Cases and control definitions were determined using administrative reco...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1677503
更新日期:2019-12-01 00:00:00
abstract::A previously healthy multigravida woman presenting with pyrexia was found to be pancytopenic at 32 weeks' gestation. The leukopenia and the thrombocytopenia responded to supportive therapy. The anemia, which was Coombs' negative, continued and was associated with a drop in fibrinogen, but both eventually returned to n...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994758
更新日期:1993-09-01 00:00:00
abstract::One hundred twenty-one patients underwent an ultrasound examination within 48 hours of delivery to assess prospectively the reliability of the diagnosis of intrauterine growth retardation. Sonographic parameters examined included the abdominal circumference, sonographic estimate of fetal weight, the head to abdominal ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999622
更新日期:1989-10-01 00:00:00
abstract::Acute physiologic changes induced by the infusion of resuscitative fluids may be harmful, resulting in the clinical sequelae of pulmonary and intraventricular hemorrhage. Using a chronically catheterized lamb model, changes in plasma sodium concentration, osmolality, hematocrit, glucose, colloid osmotic pressure, and ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-1000056
更新日期:1983-10-01 00:00:00
abstract:OBJECTIVE:Our study identified risk factors for the development of clinically identifiable catheter-associated thrombosis (CT). STUDY DESIGN:We performed a retrospective cohort study of neonates in whom a central catheter was present. A total of 1,475 catheters were identified in 766 patients during a 36-month study p...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1667377
更新日期:2019-02-01 00:00:00
abstract::The objective of this article is to prospectively investigate the efficacy of amnioinfusion as a means to reduce febrile morbidity in pregnancies complicated by chorioamnionitis. All laboring patients with a temperature > or =100.1 degrees F were approached for study participation. Exclusion criteria included amnionit...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2007-994085
更新日期:1998-01-01 00:00:00
abstract::This investigation was undertaken to determine whether histologic examination of the placenta contributed to a better understanding of the cause of intrauterine fetal growth retardation. Placentas were examined of 151 liveborn infants whose birthweights were in the lower 10th percentile for gestational age. One or mor...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999546
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:Normal initial blood glucose values in healthy newborns are not well defined and are subject to controversy. Despite substantive research, there is no single initial value of glucose that can be used with certainty of safety in newborns, and thus various protocols and cutoffs have been proposed. STUDY DESIGN...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1667293
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:This article assesses the degree of variability in the current practice of skin antiseptics used in Canadian neonatal intensive care units (NICUs) and different experiences related to each antiseptic used. METHODS:An anonymous survey was distributed to a clinical representative of each of the 124 Canadian le...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1661406
更新日期:2019-01-01 00:00:00
abstract::Novel coronavirus disease 2019 (COVID-19) infection occurring during pregnancy is associated with an increased risk of preterm delivery. This case report describes successful treatment of preterm labor during acute COVID-19 infection. Standard treatment for preterm labor may allow patients with acute COVID-19 infectio...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1709993
更新日期:2020-06-01 00:00:00
abstract::In Finland a nationwide free prenatal care system was mandated by law in 1944. At present, 99.9% of Finland's pregnant women use it. The primary aim is to provide advice and care to all women in local centers and to identify pregnant women exhibiting risk factors and refer them to specialized prenatal units located in...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999581
更新日期:1989-04-01 00:00:00