The reset hypothesis: lactation and maternal metabolism.

Abstract:

:For maternal metabolism, pregnancy ends not with delivery, but with weaning. In several recent epidemiological studies, authors have reported an association between duration of breast-feeding and reduced maternal risk of metabolic disease. These findings parallel data from animal models showing favorable changes in metabolism associated with lactation. During gestation, visceral fat accumulates, and insulin resistance and lipid and triglyceride levels increase. These changes appear to reverse more quickly, and more completely, with lactation. In this article, we review animal and human studies regarding the effects of lactation on adiposity, lipid, and glucose homeostasis. We hypothesize that lactation plays an important role in "resetting" maternal metabolism after pregnancy.

journal_name

Am J Perinatol

authors

Stuebe AM,Rich-Edwards JW

doi

10.1055/s-0028-1103034

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

81-8

issue

1

eissn

0735-1631

issn

1098-8785

journal_volume

26

pub_type

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