Current Practices of Antiseptic Use in Canadian Neonatal Intensive Care Units.

Abstract:

OBJECTIVE:This article assesses the degree of variability in the current practice of skin antiseptics used in Canadian neonatal intensive care units (NICUs) and different experiences related to each antiseptic used. METHODS:An anonymous survey was distributed to a clinical representative of each of the 124 Canadian level II and level III NICUs. RESULTS:One hundred and two respondents (82.2%), representing all Canadian provinces, completed the survey. Chlorhexidine gluconate with/without alcohol was the antiseptic most used (96%) and the antiseptic with the highest reported adverse effects (68% reported skin burns/breakdown). Other antiseptics used include povidone-iodine (35%) and isopropyl alcohol (22%). Specific guidelines for antiseptic use were available in only 50% of the units with many NICUs lacking gestational and/or chronological age restrictions. Only 23% of responders believed that there was awareness among health care providers of the adverse effects of antiseptics used. Less than half (43%) were completely satisfied with the antiseptics used in their units. CONCLUSION:Chlorhexidine gluconate is the most commonly used antiseptic in Canadian NICUs. The high number of associated adverse effects and the lack of guidelines regulating antiseptic use are of concern. Large clinical trials are urgently needed to guide practice and improve the safety of antiseptics.

journal_name

Am J Perinatol

authors

McCord H,Fieldhouse E,El-Naggar W

doi

10.1055/s-0038-1661406

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

141-147

issue

2

eissn

0735-1631

issn

1098-8785

journal_volume

36

pub_type

杂志文章
  • Extended interval dosing of gentamicin in preterm infants.

    abstract::Conventional interval dosing (CID) and extended interval dosing (EID) of gentamicin were compared in preterm infants. Gentamicin peak and trough levels, serum creatinine, urine output, and hearing screens were obtained in 40 preterm infants. Results suggest that EID is safe, provides gentamicin levels in desirable ran...

    journal_title:American journal of perinatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2004-820515

    authors: Mercado MC,Brodsky NL,McGuire MK,Hurt H

    更新日期:2004-02-01 00:00:00

  • Surgical Site Infection following Cesarean Delivery: Patient, Provider, and Procedure-Specific Risk Factors.

    abstract:OBJECTIVE:This study aims to identify risk factors for cesarean delivery (CD) surgical site infection (SSI). study design: Retrospective analysis of 2,739 CDs performed at the University of Pittsburgh in 2011. CD SSIs were defined using National Healthcare Safety Network (NHSN) criteria. Chi-square test and t-test were...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0035-1563548

    authors: Shree R,Park SY,Beigi RH,Dunn SL,Krans EE

    更新日期:2016-01-01 00:00:00

  • A rapid and safe method to detect fetal parvovirus B19 infection in amniotic fluid by polymerase chain reaction: report of a case.

    abstract::Molecular amplification of parvovirus B19 DNA in an amniotic fluid sample was used to confirm the etiologic agent of a case with fetal hydrops. The polymerase chain reaction (PCR) method used is easy and fast to perform. We have a 2-year experience on its use in clinical parvovirus B19 diagnosis. The results are avail...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994518

    authors: Nikkari S,Ekblad U

    更新日期:1995-11-01 00:00:00

  • Does Ventilatory Time Retain Its Validity in Predicting Neurodevelopmental Outcome at Two Years of Age in High-Risk Congenital Diaphragmatic Hernia Survivors?

    abstract::Objective To evaluate if in high-risk non-extracorporeal membrane oxygenation (ECMO)-treated congenital diaphragmatic hernia (CDH) survivors, ventilatory time (VT) is correlated to and can be used as clinical marker of neurodevelopmental delay at 2 years of age. Study Design Cohort study was conducted between 2008 and...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0036-1586120

    authors: Bevilacqua F,Morini F,Zaccara A,Valfrè L,Aufiero LR,Gentile S,Bagolan P,Aite L

    更新日期:2017-02-01 00:00:00

  • Neonatal outcome in growth-restricted versus appropriately grown preterm infants.

    abstract::The objective of this paper is to examine whether growth-restricted preterm infants have a different neonatal outcome than appropriately grown preterm infants. All consecutive, singleton preterm deliveries between 27-35 weeks' gestation were included over a 4-year period. Infants with congenital anomalies and infants ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2000-9423

    authors: Simchen MJ,Beiner ME,Strauss-Liviathan N,Dulitzky M,Kuint J,Mashiach S,Schiff E

    更新日期:2000-01-01 00:00:00

  • Variables associated with successful vaginal birth after one cesarean section: a proposed vaginal birth after cesarean section score.

    abstract::The objective of this study was to define the variables associated with vaginal birth after cesarean section (VBAC) and to develop a scoring system for the prediction of successful VBAC. We searched our computerized database for parturients with a history of one low-transverse cesarean section (CS) who were delivered ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2004-835961

    authors: Gonen R,Tamir A,Degani S,Ohel G

    更新日期:2004-11-01 00:00:00

  • Gentamicin levels in pregnant women with pyelonephritis.

    abstract::This study was performed at University Medical Center, Lubbock, Texas, from July 1989 to June 1990. We obtained serum gentamicin peak and trough levels in 23 pregnant women with pyelonephritis. The patients were given a loading dose of 2 mg/kg gentamicin, followed by 1.5 mg/kg gentamicin adjusted for obesity every 8 h...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994533

    authors: Graham JM,Blanco JD,Oshiro BT,Magee KP

    更新日期:1994-01-01 00:00:00

  • Sudden unexpected death in a neonate.

    abstract::A sudden and unexpected death, at 26 hours of age, of a term infant with no identifiable risk factors either in the prenatal or in the immediate neonatal period is described. The most remarkable postmortem findings were confined to the lungs, which had many areas of aspirated amniotic fluid, as well as extensive areas...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999592

    authors: Imaizumi SO,Balsara GR

    更新日期:1989-07-01 00:00:00

  • What about the Misgav-Ladach surgical technique in patients with previous cesarean sections?

    abstract:OBJECTIVE:The Misgav-Ladach technique is recommended worldwide to perform cesarean sections but there is no consensus about the appropriate technique to use in patients with previous cesarean sections. This study evaluated the feasibility of the Misgav-Ladach technique in patients with previous cesarean sections. STUD...

    journal_title:American journal of perinatology

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-0032-1323580

    authors: Bolze PA,Massoud M,Gaucherand P,Doret M

    更新日期:2013-03-01 00:00:00

  • Acyclovir treatment of primary herpes in pregnancy complicated by second trimester preterm premature rupture of membranes with term delivery: case report.

    abstract::Primary genital herpes simplex virus (HSV) infection in pregnancy is associated with an increased risk of vertical transmission to the fetus, especially with rupture of membranes. Two cases of primary herpes and two cases of recurrent herpes in pregnancy with preterm premature rupture of membranes and expectant manage...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2002-33090

    authors: Dietrich YM,Napolitano PG

    更新日期:2002-07-01 00:00:00

  • Challenges Faced in Translating the Benefits of Surfactant Replacement Therapy to a Resource-Limited Setting.

    abstract::Aim To determine the challenges, if any, in translating the benefits of surfactant replacement therapy (SRT) to a resource-limited setting. Method This was a retrospective descriptive study comparing the outcome of 75 cases who received surfactant and 69 controls who did not at the University Hospital of the West Indi...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0036-1598023

    authors: Hamilton N,Trotman H

    更新日期:2017-07-01 00:00:00

  • The History and Contributions of the Diabetes in Pregnancy Study Group of North America (1997-2015).

    abstract::The Diabetes in Pregnancy Study Group of North America (DPSG-NA) was founded in 1997 in San Antonio, Texas, out of the recognition that the field of maternal-fetal medicine should support and conduct research to address the specialized needs of pregnant women with type 1, type 2, or gestational diabetes mellitus. Sinc...

    journal_title:American journal of perinatology

    pub_type: 历史文章,杂志文章

    doi:10.1055/s-0036-1585082

    authors: Rosen JA,Langer O,Reece EA,Miodovnik M

    更新日期:2016-11-01 00:00:00

  • Multicenter Experience with Neurally Adjusted Ventilatory Assist in Infants with Severe Bronchopulmonary Dysplasia.

    abstract:OBJECTIVE: The aim of this study is to determine patterns of neurally adjusted ventilatory assist (NAVA) use in ventilator-dependent preterm infants with evolving or established severe bronchopulmonary dysplasia (sBPD) among centers of the BPD Collaborative, including indications for its initiation, discontinuation, an...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0040-1708559

    authors: McKinney RL,Keszler M,Truog WE,Norberg M,Sindelar R,Wallström L,Schulman B,Gien J,Abman SH,Bronchopulmonary Dysplasia Collaborative.

    更新日期:2020-03-24 00:00:00

  • Oral Ibuprofen and ductus arteriosus in premature infants: a randomized pilot study.

    abstract::The purpose of this study was to evaluate the feasibility of the use oral ibuprofen suspension (OIS) in the treatment of patent ductus arteriosus (PDA) in premature infants. Premature infants (

    journal_title:American journal of perinatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1055/s-2007-976550

    authors: Aly H,Lotfy W,Badrawi N,Ghawas M,Abdel-Meguid IE,Hammad TA

    更新日期:2007-05-01 00:00:00

  • Using the Probability of Cesarean from a Validated Cesarean Prediction Calculator to Predict Labor Length and Morbidity.

    abstract:OBJECTIVE:To determine if increasing predicted risk of cesarean was associated with longer labor length and increased morbidity among women undergoing induction with an unfavorable cervix. STUDY DESIGN:Using a publically available database, we evaluated whether a previously validated prediction model for cesarean deli...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0038-1675625

    authors: Hamm RF,Downes KL,Srinivas SK,Levine LD

    更新日期:2019-05-01 00:00:00

  • Nasogastric versus Orogastric Bolus Tube Feeding in Preterm Infants: Pilot Randomized Clinical Trial.

    abstract:OBJECTIVE: According to the most recent metanalysis, the best way to establish safe enteral feeding in preterm babies using nasogastric or orogastric tubes is still not well understood. This study aimed to determine the effects of bolus nasal tubes versus bolus orogastric tubes on the time required to reach full entera...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0040-1713865

    authors: Badran AT,Hashish M,Ali A,Shokeir M,Shabaan A

    更新日期:2020-07-03 00:00:00

  • Successful Treatment of Preterm Labor in Association with Acute COVID-19 Infection.

    abstract::Novel coronavirus disease 2019 (COVID-19) infection occurring during pregnancy is associated with an increased risk of preterm delivery. This case report describes successful treatment of preterm labor during acute COVID-19 infection. Standard treatment for preterm labor may allow patients with acute COVID-19 infectio...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0040-1709993

    authors: Browne PC,Linfert JB,Perez-Jorge E

    更新日期:2020-06-01 00:00:00

  • Application of transcutaneous carbon dioxide tension monitoring with low electrode temperatures in premature infants in the early postnatal period.

    abstract:OBJECTIVE:The aim of this article is to evaluate the accuracy, precision, and safety of transcutaneous carbon dioxide tension (TcPCO2) monitoring at different electrode temperatures in preterm infants in the early postnatal period. STUDY DESIGN:A total of 26 neonates with a median birth weight of 974 g (432-1,694 g) a...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0033-1352485

    authors: Hirata K,Nishihara M,Oshima Y,Hirano S,Kitajima H

    更新日期:2014-05-01 00:00:00

  • Midtrimester genetic amniocentesis of a twin gestation complicated by immediate severe fetal bradycardia with subsequent associated fetal anomalies.

    abstract::We present an unusual complication of midtrimester genetic amniocentesis of a monochorionic twin gestation in which prolonged fetal bradycardia of 60 to 80 beats per minute sustained over two hours was associated with multiple subsequent fetal anomalies. These included: microcephaly, bilateral closed-lip schizencephal...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994354

    authors: Sherer DM,Salafia CM

    更新日期:1996-08-01 00:00:00

  • Meconium plugs and intussusception in a premature infant.

    abstract::Neonatal intussusception in premature infants is uncommon and may mimic other abdominal disorders. We present a case of intussusception in a very low birthweight neonate. Presenting signs initially suggested necrotizing enterocolitis and meconium disease, and the diagnosis was confirmed at laparotomy. ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999916

    authors: Glick B,Alpan G,Vinograd I,Udassin R,Mogle P,Eyal F

    更新日期:1985-04-01 00:00:00

  • Association of paroxysmal supraventricular tachycardia and periventricular leukomalacia.

    abstract::Periventricular leukomalacia, a condition characterized by hpoxic-ischemic infarction of deep cerebral white matter, can now be recognized by cranial sonography. The case presented here demonstrates the association of periventricular leukomalacia present at birth with intrauterine paroxysmal supraventricular tachycard...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999826

    authors: Donn SM,Bowerman RA

    更新日期:1986-01-01 00:00:00

  • Double phototherapy with high irradiance compared with single phototherapy in neonates with hyperbilirubinemia.

    abstract::The purpose of this study is to compare the effectiveness of double phototherapy versus single conventional phototherapy in decreasing serum bilirubin levels in jaundiced neonates. Forty-two preterm infants who were less than 37 weeks' gestational age and less than 2000 g birthweight with nonhemolytic jaundice were al...

    journal_title:American journal of perinatology

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2007-994446

    authors: Kang JH,Shankaran S

    更新日期:1995-05-01 00:00:00

  • Society for Maternal-Fetal Medicine's Fellow Research Series 2018: Manuscripts of the Year.

    abstract:: ...

    journal_title:American journal of perinatology

    pub_type: 社论

    doi:10.1055/s-0038-1676585

    authors: Metz TD,Gill L,Silver RM,Society for Maternal-Fetal Medicine Fellowship Affairs Committee.

    更新日期:2019-01-01 00:00:00

  • Use of noninvasive high-frequency ventilation in the neonatal intensive care unit: a retrospective review.

    abstract:OBJECTIVE:The aim of the article is to review the effectiveness of neonatal noninvasive high-frequency ventilation (NIHFV) in preventing endotracheal mechanical ventilation. STUDY DESIGN:Retrospective case series including all 79 instances of NIHFV use at four participating centers between July 2010 and September 2012...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0034-1381317

    authors: Mukerji A,Singh B,Helou SE,Fusch C,Dunn M,Belik J,Shah V

    更新日期:2015-02-01 00:00:00

  • Reducing Alarm Fatigue in Two Neonatal Intensive Care Units through a Quality Improvement Collaboration.

    abstract:OBJECTIVE:To reduce nonactionable oximeter alarms by 80% without increasing time infants were hypoxemic (oxygen saturation [SpO2] ≤ 80%) or hyperoxemic (SpO2 > 95% while on supplemental oxygen). STUDY DESIGN:In 2015, a multidisciplinary team at Connecticut Children's Medical Center initiated a quality improvement proj...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0038-1653945

    authors: Johnson KR,Hagadorn JI,Sink DW

    更新日期:2018-11-01 00:00:00

  • Relationship of Early Pregnancy Waist-to-Hip Ratio versus Body Mass Index with Gestational Diabetes Mellitus and Insulin Resistance.

    abstract:OBJECTIVE:To determine the risk of gestational diabetes mellitus (GDM) and insulin resistance (IR) in obesity defined by body mass index (BMI), waist-to-hip ratio (WHR), or both combined. METHODS:Secondary analysis of a randomized multicenter trial of antioxidant supplementation versus placebo in nulliparous low-risk ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1055/s-0035-1562928

    authors: Basraon SK,Mele L,Myatt L,Roberts JM,Hauth JC,Leveno KJ,Varner MW,Wapner RJ,Thorp JM Jr,Peaceman AM,Ramin SM,Sciscione A,Tolosa JE,Sorokin Y,Eunice Kennedy Shriver National Institute of Child Health and Human Development Mate

    更新日期:2016-01-01 00:00:00

  • Providing Support for Neonatal Intensive Care Unit Health Care Professionals: A Bereavement Debriefing Program.

    abstract:OBJECTIVE: The aim of this study is to evaluate formal bereavement debriefing sessions after infant death on neonatal intensive care unit (NICU) staff. STUDY DESIGN: Prospective mixed methods study. Pre- and postbereavement debriefing intervention surveys were sent to clinical staff. Evaluation surveys were distribute...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0040-1716481

    authors: Hawes K,Goldstein J,Vessella S,Tucker R,Lechner BE

    更新日期:2020-09-07 00:00:00

  • Variation in the management of persistent pulmonary hypertension of the newborn: a survey of physicians in Canada, Australia, and New Zealand.

    abstract:BACKGROUND:Despite advances in management of persistent pulmonary hypertension of the newborn (PPHN), the risk of mortality and adverse neurological sequelae remains high. Characterizing variation in practices is a crucial step toward improved patient outcome. OBJECTIVE:Evaluate intensive care practices in Canada and ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0032-1310523

    authors: Shivananda S,Ahliwahlia L,Kluckow M,Luc J,Jankov R,McNamara P

    更新日期:2012-08-01 00:00:00

  • Prenatal sonographic findings associated with malignant astrocytoma following normal early third-trimester ultrasonography.

    abstract::We present an unusual case in which sonographic assessment at 33 weeks' gestation, 5 weeks following a normal fetal anatomical survey and biometry, demonstrated a large, irregular-shaped, echogenic, suprasellar midline intracranial mass occupying the anterior and middle fossas. Associated severe obstructive hydrocepha...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994064

    authors: Sylvestre G,Sherer DM

    更新日期:1998-01-01 00:00:00

  • Outpatient oral misoprostol for prolonged pregnancies: a pilot investigation.

    abstract:UNLABELLED:We evaluated the effectiveness of oral misoprostol for outpatient cervical ripening and labor induction in prolonged pregnancies. We performed a randomized, double-blind, placebo-controlled study of women at 40 to 42 weeks' gestation with well-dated pregnancies, singleton gestations, Bishop scores less than ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1055/s-0029-1220790

    authors: Gaffaney CA,Saul LL,Rumney PJ,Morrison EH,Thomas S,Nageotte MP,Wing DA

    更新日期:2009-10-01 00:00:00