Abstract：
OBJECTIVE: The aim of this study is to determine patterns of neurally adjusted ventilatory assist (NAVA) use in ventilator-dependent preterm infants with evolving or established severe bronchopulmonary dysplasia (sBPD) among centers of the BPD Collaborative, including indications for its initiation, discontinuation, and outcomes. STUDY DESIGN: Retrospective review of infants with developing or established sBPD who were placed on NAVA after ≥4 weeks of mechanical ventilation and were ≥ 30 weeks of postmenstrual age (PMA). RESULTS: Among the 13 sites of the BPD collaborative, only four centers (31%) used NAVA in the management of infants with evolving or established BPD. A total of 112 patients met inclusion criteria from these four centers. PMA, weight at the start of NAVA and median number of days on NAVA, were different among the four centers. The impact of NAVA therapy was assessed as being successful in 67% of infants, as defined by the ability to achieve respiratory stability at a lower level of ventilator support, including extubation to noninvasive positive pressure ventilation or support with a home ventilator. In total 87% (range: 78-100%) of patients survived until discharge. CONCLUSION: We conclude that NAVA can be used safely and effectively in selective infants with sBPD. Indications and current strategies for the application of NAVA in infants with evolving or established BPD, however, are highly variable between centers. Although this pilot study suggests that NAVA may be successfully used for the management of infants with BPD, sufficient experience and well-designed clinical studies are needed to establish standards of care for defining the role of NAVA in the care of infants with sBPD.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
McKinney RL,Keszler M,Truog WE,Norberg M,Sindelar R,Wallström L,Schulman B,Gien J,Abman SH,Bronchopulmonary Dysplasia Collaborative.doi
10.1055/s-0040-1708559subject
Has Abstractpub_date
2020-03-24 00:00:00eissn
0735-1631issn
1098-8785pub_type
杂志文章abstract：:Our objective was to compare the incidence of recurrent spontaneous preterm delivery (SPTD) in patients with cervical cerclage treated with weekly 17 alpha-hydroxyprogesterone caproate (17P) injections versus daily outpatient nursing surveillance (ONS) without 17P. Included in this retrospective cohort study were sing...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2008-1064935
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVE:The aim of this article is to evaluate the accuracy, precision, and safety of transcutaneous carbon dioxide tension (TcPCO2) monitoring at different electrode temperatures in preterm infants in the early postnatal period. STUDY DESIGN:A total of 26 neonates with a median birth weight of 974 g (432-1,694 g) a...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0033-1352485
更新日期：2014-05-01 00:00:00
abstract：:One hundred twenty-one patients underwent an ultrasound examination within 48 hours of delivery to assess prospectively the reliability of the diagnosis of intrauterine growth retardation. Sonographic parameters examined included the abdominal circumference, sonographic estimate of fetal weight, the head to abdominal ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999622
更新日期：1989-10-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to evaluate the clinical characteristics of neonates with hydrops fetalis to improve recognition of the disease. PATIENTS AND METHODS:The clinical data of 10 neonates with hydrops fetalis were retrospectively studied. Prenatal characteristics, causes, clinical features, and pr...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1552934
更新日期：2015-11-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2000-10004
更新日期：2000-01-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2004-829870
更新日期：2004-07-01 00:00:00
abstract：:The presence of the maternal warm antibody in pregnancy should not be ignored. As there is risk of both maternal and fetal anemia, both patients need to be followed for the development of such. Serial complete blood counts in the mother and treatment if significant fetal anemia develops should be considered. Serial am...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994196
更新日期：1996-01-01 00:00:00
abstract：:A hospital-based case-controlled study was undertaken to determine maternal and neonatal characteristics associated with fractured clavicle. A total of 11,604 consecutive vaginal deliveries of liveborn infants in vertex presentation at the Mount Sinai Hospital from 1988 to 1990 were reviewed. Maternal and neonatal cha...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994546
更新日期：1994-09-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2008-1040766
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journal_title：American journal of perinatology
pub_type： 杂志文章,评审
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journal_title：American journal of perinatology
pub_type： 杂志文章
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更新日期：1995-05-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-986679
更新日期：2007-09-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993962
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVE:To review developmental outcomes of neonates with mild hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH). STUDY DESIGN:Neonates ≥35 weeks' gestation with mild HIE/TH (TH group, n = 30) were matched with healthy term-born infants (control group, n = 30) and reviewed for the prese...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1676973
更新日期：2019-11-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999987
更新日期：1984-01-01 00:00:00
abstract：:The primary objective of this study was to determine whether having the sickle cell trait is independently associated with preeclampsia. We performed a retrospective cohort study of 1998 pregnant patients who either did or did not have the sickle cell trait. All patients were screened for the sickle trait using the "S...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2003-37953
更新日期：2003-01-01 00:00:00
abstract：:Premature birth before 37 weeks of gestation is a significant public health problem. Each year, 4.5 million premature infants are born worldwide. Despite extensive research and a variety of interventions, the rate of preterm birth has steadily increased over the past 20 years and reached a high of 12.8% in 2006. The e...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2008-1061497
更新日期：2008-03-01 00:00:00
abstract：BACKGROUND:Retinopathy of prematurity (ROP) is a significant cause of childhood blindness. AIM:The aim of this study is to determine the feasibility of remifentanil analgesia during laser treatment of ROP performed in the neonatal intensive care unit (NICU). PATIENTS AND METHODS:Remifentanil was infused continuously ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0034-1370348
更新日期：2014-11-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
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更新日期：2019-10-11 00:00:00
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journal_title：American journal of perinatology
pub_type： 临床试验,杂志文章
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2000-13456
更新日期：2000-01-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-970080
更新日期：2007-03-01 00:00:00
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journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2002-25309
更新日期：2002-04-01 00:00:00
abstract：:Caffeine is commonly used in the treatment of apnea of prematurity. The skin of preterm infants varies considerably in its level of maturity. To understand skin absorption in low birthweight infants (less than 1500 gm) with gestational age between 26 and 34 weeks, a group of 56 preterm babies was studied after percuta...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999282
更新日期：1992-09-01 00:00:00
abstract：OBJECTIVE: Previous analyses of neonatal intensive care units (NICU) antimicrobial stewardship programs have identified key contributors to overall antibiotic use, including prolonged empiric therapy >48 hours for early-onset sepsis (EOS). However, most were performed in mixed NICU settings with onsite birthing units, ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1722600
更新日期：2021-01-17 00:00:00
abstract：:Antihistamines are commonly used to treat nausea and vomiting of pregnancy (NVP). We re-analyzed the 24 primary studies cited in a 1997 meta-analysis that concluded antihistamine use for NVP was safe as they had been studied in more than 200,000 participating women and the pooled odds ratio for congenital malformation...
journal_title：American journal of perinatology
pub_type： 杂志文章,meta分析
doi：10.1055/s-0033-1358772
更新日期：2014-09-01 00:00:00
abstract：:Cardiovascular disease (CVD) is the leading cause of death and disability among women, with more than half occurring in individuals with hypertension. New blood pressure criteria for the diagnosis of hypertension from the American College of Cardiology/American Heart Association recognize that there is no specific blo...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0038-1669441
更新日期：2019-03-01 00:00:00
abstract：:In the present study we examined whether the vitamin D3 metabolites, 25-hydroxyvitamin D and 1-25-dihydroxycholecalciferol affected the production of the prostaglandins PGE2 and PGF2 alpha in human fetal membranes and placenta in vitro. Human amnion, chorion, decidual, and placental cells were maintained in primary mo...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999564
更新日期：1989-04-01 00:00:00
abstract：:A sudden and unexpected death, at 26 hours of age, of a term infant with no identifiable risk factors either in the prenatal or in the immediate neonatal period is described. The most remarkable postmortem findings were confined to the lungs, which had many areas of aspirated amniotic fluid, as well as extensive areas...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999592
更新日期：1989-07-01 00:00:00
abstract：:Ehlers-Danlos syndrome type IV (EDS IV) is a rare but serious disorder of connective tissue that is characterized by the abnormal production or secretion of type III collagen. Experience with pregnant patients exhibiting this syndrome is limited. This report describes the successful management of a pregnancy in a woma...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999756
更新日期：1987-04-01 00:00:00
