Abstract:
:The objective of this study was to evaluate the effect of prophylactic antibiotic treatment on prenatal and neonatal outcome after preterm premature rupture of the membranes (P-PROM). The study population consisted of 172 pregnant women admitted to the Rabin Medical Center in Israel with P-PROM at 23-34 gestational weeks. The patients were divided into two groups by mode of expectant management-prophylactic ampicillin and erythromycin (study group, n = 121) or observation only (control group, n = 51) and compared for neonatal outcome. There were no significant differences between the groups in age, gravidity, parity, or gestational age at admission. Significantly more women in the study group had an interval of more than 24 hours from onset of P-PROM to delivery (98 women, 81%) than the control group (32 women, 63%) (p = 0.001). The neonatal mortality rate was significantly lower in the study group (6.6%) than the control group (1 7.6%) (p = 0.03). The lower neonatal mortality rate associated with prophylactic antibiotic treatment in P-PROM has important clinical implications for the effectiveness of this type of management.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Bar J,Maayan-Metsger A,Hod M,Ben Rafael Z,Orvieto R,Shalev Y,Sirota Ldoi
10.1055/s-2000-10004subject
Has Abstractpub_date
2000-01-01 00:00:00pages
237-41issue
5eissn
0735-1631issn
1098-8785journal_volume
17pub_type
杂志文章abstract::To minimize the selection bias inherent in reporting results gathered only in neonatal intensive care units, this study presents survival and respiratory course data on all 299 infants of birthweight 501 to 1500 gm liveborn to residents of the North Central Illinois Perinatal Region in 1985-1986. The survival rate was...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999632
更新日期:1989-10-01 00:00:00
abstract::The objective of this paper is to determine whether acyclovir suppression provides a greater cost savings over no medical therapy in the management of recurrent genital herpes (HSV) in pregnancy. Estimates of the risk of HSV recurrence and cesarean delivery rates in acyclovir-treated and -untreated patients and freque...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993900
更新日期:1998-01-01 00:00:00
abstract::Major akinesia with arthrogryposis and craniosynostosis at birth mimics irreversible disorders of the nervous system of pejorative outcome. In this context, the early detection of anti-acetylcholine fetal receptor antibodies in the mother may allow rapid diagnosis of transient neonatal myasthenia of favorable prognosi...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2002-34468
更新日期:2002-08-01 00:00:00
abstract::An abdominal gunshot wound in pregnancy warrants prompt surgical exploration but does not mandate uterine evacuation. Despite an entry and exit bullet wound to the uterus an apparent desire for pregnancy termination, a conservative approach was adopted with primary repair of the uterus, in conjunction with surgical re...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999691
更新日期:1988-07-01 00:00:00
abstract::A patient with congenital antithrombin III deficiency and a history of thromboembolic events prior to pregnancy was successfully treated with subcutaneous heparin alone throughout two pregnancies. Although adjuvant antithrombin III infusions may have a role in the treatment of this disorder, especially in the peripart...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994748
更新日期:1993-07-01 00:00:00
abstract::A sudden and unexpected death, at 26 hours of age, of a term infant with no identifiable risk factors either in the prenatal or in the immediate neonatal period is described. The most remarkable postmortem findings were confined to the lungs, which had many areas of aspirated amniotic fluid, as well as extensive areas...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999592
更新日期:1989-07-01 00:00:00
abstract::Serial ultrasound measurements of the fetus under investigation is an important indicator of fetal growth, and thus fetal health. To assess how reliable those measurements are, a videotape was made, and, utilizing an ultrasound machine that allowed the placement of callipers on the videotape, the dispersion of the mea...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999271
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVE:To review developmental outcomes of neonates with mild hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH). STUDY DESIGN:Neonates ≥35 weeks' gestation with mild HIE/TH (TH group, n = 30) were matched with healthy term-born infants (control group, n = 30) and reviewed for the prese...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1676973
更新日期:2019-11-01 00:00:00
abstract::This study considers whether admission to the hospital of a patient diagnosed with a short cervix delayed delivery, prevented preterm delivery, and/or decreased the rate of change in the cervical length (CL) on follow-up measurements. The design was a retrospective cohort study of women carrying singleton pregnancies ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2006-958164
更新日期:2007-01-01 00:00:00
abstract::The objective of this article is to prospectively investigate the efficacy of amnioinfusion as a means to reduce febrile morbidity in pregnancies complicated by chorioamnionitis. All laboring patients with a temperature > or =100.1 degrees F were approached for study participation. Exclusion criteria included amnionit...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2007-994085
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE: The purpose of this study was to compare the nulliparous-term-singleton-vertex (NTSV) and the Society of Maternal-Fetal Medicine (SMFM) cesarean birth metrics as tools for quality improvement efforts based on hospital size. MATERIALS AND METHODS: Cesarean birth rates from 275 hospitals from six states were ...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
doi:10.1055/s-0037-1607985
更新日期:2018-03-01 00:00:00
abstract:AIMS:Detection and careful stratification of fetal heart rate (FHR) is extremely important in all pregnancies. The most lethal cardiac rhythm disturbances occur during apparently normal pregnancies where FHR and rhythm are regular and within normal or low-normal ranges. These hidden depolarization and repolarization ab...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1372430
更新日期:2014-08-01 00:00:00
abstract::Numerous diagnostic pitfalls were noted among 6 infants with infradiaphragmatic total anomalous pulmonary venous drainage, including prolonged moderate respiratory distress in 2 infants, normal cardiac examination in 2, normal electrocardiograms in 2, arterial PO2 in excess of 100 torr in 3 cases, right radial/umbilic...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-1000010
更新日期:1984-04-01 00:00:00
abstract:OBJECTIVE:To estimate the natural history of cervical effacement in labor. STUDY DESIGN:This is a retrospective cohort study of term, vertex, singletons who reached 10 cm of cervical dilation from 2010 to 2014. Interval-censored regression was used to estimate the median number of hours between changes in effacement (...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1645858
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to assess if women with arrested preterm labor (PTL) have an increased risk of preterm delivery (PTD) compared with healthy pregnant women, and if digital examination, fetal fibronectin (fFn) and cervical length (CL) are prognostic markers for PTD after arrested PTL. STUDY DESIGN:Pro...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1374818
更新日期:2015-01-01 00:00:00
abstract::We present a case of congenital parvovirus B19 infection in a term neonate manifested with isolated massive hydrothorax and mild anemia. Parvovirus B19 DNA was detected in maternal and neonatal blood as well as in pleural fluid despite lack of suggestive serology. ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0028-1085621
更新日期:2008-10-01 00:00:00
abstract::We sought to determine the detection (clinical or sonographic) rate of macrosomic newborns (at least 4000 g) and the peripartum factors among those who were or were not identified accurately. We retrospectively reviewed all deliveries over 1 year and all maternal and neonatal charts of macrosomic newborns delivered du...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0028-1095187
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:Surfactant and noninvasive ventilation are two major strategies for the treatment of neonates with respiratory distress syndrome (RDS). However, the optimal time for surfactant administering is yet controversial. This study compared the early and rescue Calsurf administration in preterm infants with RDS. STU...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1055/s-0039-1678530
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the interobserver reliability of fetal heart rate (FHR) pattern definition and interpretation assessed by physicians at various levels of training using standard Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) definitions and standard principles of interpret...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0032-1326991
更新日期:2013-06-01 00:00:00
abstract::We sought to determine the incidence of cord entanglement around any part of fetal body during early gestation using three-dimensional (3D) sonography. A prospective consecutive study was designed and 3D ultrasound was performed. Two hundred thirty-seven singleton pregnancies between 13 and 16 weeks were included. Cor...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0028-1110090
更新日期:2009-05-01 00:00:00
abstract::Five full term infants with necrotizing enterocolitis, confirmed histologically, presented in the first five days of life. All passed grossly bloody stools and three mucosal casts. Severe perinatal asphyxia with accompanying secondary hyperammonemia was present in all, and abnormal liver function studies were present ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-1000050
更新日期:1983-10-01 00:00:00
abstract:OBJECTIVE:This study aims to develop a scoring system for the prediction of bronchopulmonary dysplasia (BPD). METHODS:Medical records of 652 infants whose gestational age and birth weight were below 32 weeks and 1,500 g, respectively, and who survived beyond 28th postnatal day were reviewed retrospectively. Logistic r...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1393935
更新日期:2015-06-01 00:00:00
abstract::Ehlers-Danlos syndrome type IV (EDS IV) is a rare but serious disorder of connective tissue that is characterized by the abnormal production or secretion of type III collagen. Experience with pregnant patients exhibiting this syndrome is limited. This report describes the successful management of a pregnancy in a woma...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999756
更新日期:1987-04-01 00:00:00
abstract:OBJECTIVE:Placenta previa and prior cesarean delivery are known risk factors for placenta accreta. However, other risk factors have not been identified. Our objective was to examine risk factors for accreta using data collected prospectively in a large multicenter cohort. STUDY DESIGN:Secondary analysis of women with ...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
doi:10.1055/s-0033-1361833
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the pregnancy outcome of two different management strategies: outpatient versus inpatient in women with prenatal diagnosis of vasa previa. MATERIALS AND METHODS:This is a retrospective cohort study conducted at a single tertiary center. Women with a prenatally diagnosed v...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1669396
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate the clinical characteristics of neonates with hydrops fetalis to improve recognition of the disease. PATIENTS AND METHODS:The clinical data of 10 neonates with hydrops fetalis were retrospectively studied. Prenatal characteristics, causes, clinical features, and pr...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1552934
更新日期:2015-11-01 00:00:00
abstract::The purpose of this study was to evaluate the feasibility of the use oral ibuprofen suspension (OIS) in the treatment of patent ductus arteriosus (PDA) in premature infants. Premature infants (= 35 weeks) age 2 to 7 days who suffered from respiratory distress and had been diagnosed with PDA were included in this stu...
journal_title:American journal of perinatology
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-2007-976550
更新日期:2007-05-01 00:00:00
abstract::The significance and management of prepartum bradycardia is not well established in prepartum fetal assessment. The incidence of prolonged bradycardia was 3.5% (45 per 1284), defined as a decrease of greater than or equal to 40 beats per minute of the fetal heart rate (FHR) below the baseline for at least 2 minutes. T...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999972
更新日期:1985-10-01 00:00:00
abstract::The use of transabdominal vibroacoustic stimulation has been shown to improve the efficiency of antepartum fetal surveillance. The ability of the fetus to habituate to such a stimulus has also been suggested as a means of assessing the function of the central nervous system. The purpose of this blinded prospective inv...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999420
更新日期:1991-11-01 00:00:00
abstract:OBJECTIVE:This study was aimed to evaluate the prevalence of sonographic markers for placenta accreta spectrum (PAS) in pregnancies at low-risk for PAS. STUDY DESIGN:Pregnant women at low-risk for PAS presenting for routine second trimester ultrasound who enrolled in the study were evaluated prospectively for sonograp...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1676488
更新日期:2019-07-01 00:00:00