The neonatal autopsy: can it be revived?

Abstract:

OBJECTIVES:To describe the trend and factors associated with the autopsy over the past decade at a level III neonatal intensive care unit (NICU) where all patients are presented with an option. STUDY DESIGN:Retrospective study of the autopsy in a cohort of infants who died in the NICU from January 1, 2001, to December 31, 2010. RESULTS:Of 446 deaths, 33.9% received the autopsy and rates decreased from the 2 years prior to the study. The autopsy was associated with gestational age at birth and chronologic age at death. On multivariable logistic regression analyses, the odds of an autopsy increased with gestational age (p = 0.001), death in the postneonatal period (odds ratio [OR] = 2.01, 95% confidence interval [CI] = 1.28, 3.16), and absence of a major congenital anomaly (OR = 1.96, 95% CI = 1.22, 3.23). CONCLUSION:Autopsy rates continue to decline despite ensuring that all parents are presented with the option. Infants born at term and those who die after 1 month without known congenital anomalies are most likely to receive the autopsy. The persistently low rates may highlight the importance of helping families understand that the autopsy has utility even when the cause of death may appear to be obvious.

journal_name

Am J Perinatol

authors

Swinton CH,Weiner J,Okah FA

doi

10.1055/s-0032-1332798

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

739-44

issue

9

eissn

0735-1631

issn

1098-8785

journal_volume

30

pub_type

杂志文章
  • Intravenous immunoglobulins for neonatal alloimmune neutropenia refractory to recombinant human granulocyte colony-stimulating factor.

    abstract::Neonatal alloimmune neutropenia (NAN) results from neutrophil destruction by transplacental maternal neutrophil-specific immunoglobulin G (IgG) antibodies directed against the antigen inherited from the father. Treatment is usually based on recombinant human granulocyte colony-stimulating factor (G-CSF) and prevention...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0030-1270113

    authors: Desenfants A,Jeziorski E,Plan O,Rodière M,Rimbert M,Muller JY,Taïb J,Cambonie G

    更新日期:2011-06-01 00:00:00

  • Do postnatal glucocorticoids and retinopathy of prematurity relate?

    abstract::To study a possible relation between the use of postnatal glucocorticoids and the incidence and severity of retinopathy of prematurity (ROP), we conducted a retrospective study over a 4-year period that compared data of 161 preterm infants treated with hydrocortisone for bronchopulmonary dysplasia (BPD) with the data ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2000-13437

    authors: Termote J,Schalij-Delfos NE,Donders AR,Cats BP

    更新日期:2000-01-01 00:00:00

  • Provider Awareness, Understanding and Use of NICHD Neonatal Research Network Outcomes Estimator.

    abstract::Introduction Our aim was to survey clinicians to assess awareness and utilization of the NICHD Neonatal Research Network outcomes estimator, which allows clinicians to use multiple factors to better estimate the likelihood that intensive care will benefit the delivered neonate. Study Design The survey tool included a ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0036-1582396

    authors: Peterson S,Gonik B

    更新日期:2016-08-01 00:00:00

  • Predicting placental abruption and previa in women with a previous cesarean delivery.

    abstract::The purpose of this study was to determine if placental abruption or previa in women with a history of a prior cesarean delivery (CD) can be predicted. A retrospective cohort study of pregnant women with previous CD was conducted in 17 centers between 1996 and 2000. Women developing placenta previa or abruption in the...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-2007-981430

    authors: Odibo AO,Cahill AG,Stamilio DM,Stevens EJ,Peipert JF,Macones GA

    更新日期:2007-05-01 00:00:00

  • Accurate ultrasonic estimation of fetal weight.

    abstract::The accuracy of eight ultrasonic fetal weight formulas were analyzed in 1099 fetuses who underwent real-time ultrasound examination within 72 hours prior to delivery. Shepard's formula was most consistently found to give the lowest systematic and random errors throughout all weight categories, though Deter's formula h...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999944

    authors: Ott WJ,Doyle S,Flamm S

    更新日期:1985-07-01 00:00:00

  • Do neonatal outcomes differ depending on the cause of preterm birth? A comparison between spontaneous birth and iatrogenic delivery for preeclampsia.

    abstract::We compared short-term neonatal outcomes between premature infants with spontaneous preterm birth (s-PTB) and those delivered due to preeclampsia (PEC). Data were collected from women with singleton pregnancies admitted with spontaneous preterm labor (PTL) (2002 to 2005) and PEC (2005 to 2007). Patients delivering 24 ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0029-1234036

    authors: Bastek JA,Srinivas SK,Sammel MD,Elovitz MA

    更新日期:2010-02-01 00:00:00

  • Remifentanil analgesia during laser treatment for retinopathy of prematurity: a practical approach in neonatal intensive care unit.

    abstract:BACKGROUND:Retinopathy of prematurity (ROP) is a significant cause of childhood blindness. AIM:The aim of this study is to determine the feasibility of remifentanil analgesia during laser treatment of ROP performed in the neonatal intensive care unit (NICU). PATIENTS AND METHODS:Remifentanil was infused continuously ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0034-1370348

    authors: Demirel N,Bas AY,Kavurt S,Celik IH,Yucel H,Turkbay D,Hekimoğlu E,Koc O

    更新日期:2014-11-01 00:00:00

  • Distribution of Late-Onset Neonatal Sepsis Pathogens Differs in Inpatient and Outpatient Settings.

    abstract:OBJECTIVE:We sought to examine pathogen distribution and clinical presentation of late-onset sepsis (LOS) at an urban tertiary care center. STUDY DESIGN:We performed a retrospective review of all culture-confirmed cases of LOS presenting to our institution from 2013 to 2017. Medical records were evaluated for demograp...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0038-1675643

    authors: Black CG,Tavares L,Stachel A,Ratner AJ,Randis TM

    更新日期:2019-09-01 00:00:00

  • Liposomal amphotericin B in neonates with invasive candidiasis.

    abstract::Liposomal amphotericin B L-Amp B, a novel formulation of Amp B, is effective for the treatment of invasive fungal infections in children and adults and is associated with less toxicity than the conventional preparation. Data on the use of L-Amp B in neonates is scarce. We describe the clinical course of two premature ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994337

    authors: al Arishi H,Frayha HH,Kalloghlian A,al Alaiyan S

    更新日期:1997-10-01 00:00:00

  • Sonographic measurement of the fetal iliac bone: growth and relation to femur length in assessment of gestational age.

    abstract::Diagnostic ultrasonography has given us the opportunity to diagnose several congenital malformations in utero. Skeletal dysplasias is a heterogeneous group of disorders of the skeleton. Although disorders of bone growth are often diagnosed in utero, it is usually a general diagnosis because the exact syndrome cannot b...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994638

    authors: Jaffe R,Santolaya J,Warsof SL

    更新日期:1993-03-01 00:00:00

  • Severe Maternal Morbidity and Hospital Cost among Hospitalized Deliveries in the United States.

    abstract:OBJECTIVE:The objective of this study was to estimate the contemporary national rate of severe maternal morbidity (SMM) and its associated hospital cost during delivery hospitalization. STUDY DESIGN:We conducted a retrospective study identifying all delivery hospitalizations in the United States between 2011 and 2012....

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0038-1649481

    authors: Chen HY,Chauhan SP,Blackwell SC

    更新日期:2018-11-01 00:00:00

  • The detection of macrosomia at a teaching hospital.

    abstract::We sought to determine the detection (clinical or sonographic) rate of macrosomic newborns (at least 4000 g) and the peripartum factors among those who were or were not identified accurately. We retrospectively reviewed all deliveries over 1 year and all maternal and neonatal charts of macrosomic newborns delivered du...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0028-1095187

    authors: Heywood RE,Magann EF,Rich DL,Chauhan SP

    更新日期:2009-02-01 00:00:00

  • Discordancy in triplets.

    abstract::Discordancy in twins is generally described as a weight difference between the fetuses of 15 to 25% and its prevalence in normal twin gestations is estimated at 15 to 29%. The present study was performed in order to determine the frequency of discordant newborns in uncomplicated triplet gestations. One hundred and fou...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994724

    authors: Mordel N,Benshushan A,Zajicek G,Laufer N,Schenker JG,Sadovsky E

    更新日期:1993-05-01 00:00:00

  • Neurodevelopmental Outcomes in Neonates with Mild Hypoxic Ischemic Encephalopathy Treated with Therapeutic Hypothermia.

    abstract:OBJECTIVE:To review developmental outcomes of neonates with mild hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH). STUDY DESIGN:Neonates ≥35 weeks' gestation with mild HIE/TH (TH group, n = 30) were matched with healthy term-born infants (control group, n = 30) and reviewed for the prese...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0038-1676973

    authors: Rao R,Trivedi S,Distler A,Liao S,Vesoulis Z,Smyser C,Mathur AM

    更新日期:2019-11-01 00:00:00

  • Apgar Score at 5 Minutes Is Associated with Mortality in Extremely Preterm Infants Even after Transfer to an All Referral NICU.

    abstract:OBJECTIVE:The Apgar score has been shown to have utility in predicting mortality in the extremely preterm infant in delivery hospital populations, where most mortality occurs within 12 hours of birth. We tested the hypothesis that the 5 minute Apgar score would remain associated with mortality in extremely preterm infa...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0035-1554803

    authors: Bartman T,Bapat R,Martin EM,Shepherd EG,Nelin LD,Reber KM

    更新日期:2015-11-01 00:00:00

  • Hypertrophic cardiomyopathy in infants of diabetic mothers: an update.

    abstract::Infants of diabetic mothers (IDMs) are at known risk for developing a hypertrophic type of cardiomyopathy. The severity of IDM cardiomyopathy can vary from an incidental finding on echocardiography to an infant with severe symptoms of congestive heart failure. The purpose of this article is to review the pathophysiolo...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,评审

    doi:10.1055/s-2007-999722

    authors: Reller MD,Kaplan S

    更新日期:1988-10-01 00:00:00

  • Neonatal hepatoblastoma: two cases posing a diagnostic dilemma, with a review of the literature.

    abstract::Hepatoblastoma accounts for less than 1% of all pediatric malignancies. However, it remains the most common malignant tumor of the liver in newborns. Less than 10% of hepatoblastoma cases are diagnosed in the neonatal period. The diagnosis can be very difficult due to the wide spectrum of presentation and differences ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,评审

    doi:10.1055/s-2005-872592

    authors: Sallam A,Paes B,Bourgeois J

    更新日期:2005-11-01 00:00:00

  • Pregnancy management and successful outcome of Ehlers-Danlos syndrome type IV.

    abstract::Ehlers-Danlos syndrome type IV (EDS IV) is a rare but serious disorder of connective tissue that is characterized by the abnormal production or secretion of type III collagen. Experience with pregnant patients exhibiting this syndrome is limited. This report describes the successful management of a pregnancy in a woma...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999756

    authors: Weinbaum PJ,Cassidy SB,Campbell WA,Rickles FR,Vintzileos AM,Nochimson DJ,Tsipouras P

    更新日期:1987-04-01 00:00:00

  • Equation for predicting weight gain in very low-birth-weight infants.

    abstract::I developed a single equation that simulated previously published growth charts for very low-birth-weight infants, using birth weight as the only variable. The intent of this study was to validate the equation using infants admitted to our neonatal intensive care unit (NICU) and to determine if this equation could be ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-993914

    authors: Meetze WH

    更新日期:1998-02-01 00:00:00

  • Prenatal sonographic findings associated with malignant astrocytoma following normal early third-trimester ultrasonography.

    abstract::We present an unusual case in which sonographic assessment at 33 weeks' gestation, 5 weeks following a normal fetal anatomical survey and biometry, demonstrated a large, irregular-shaped, echogenic, suprasellar midline intracranial mass occupying the anterior and middle fossas. Associated severe obstructive hydrocepha...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994064

    authors: Sylvestre G,Sherer DM

    更新日期:1998-01-01 00:00:00

  • References Values of Fetal Heart Myocardial Volume by Three-Dimensional Ultrasound using Spatiotemporal Image Correlation and Virtual Organ Computer-Aided Analysis Methods and Their Applicability in Pregestational Diabetic Women.

    abstract:OBJECTIVE: To determine reference values for myocardial volume of the fetal heart using three-dimensional ultrasound with spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL) and to assess their applicability in women with pregestational diabetes. STUDY DESIGN: This retrospective c...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0039-3400983

    authors: Melo Júnior JF,Bravo-Valenzuela NJ,Nardozza LMM,Peixoto AB,Mattar R,Martins WP,Pares DBDS,Araujo Júnior E

    更新日期:2019-12-13 00:00:00

  • Serum unconjugated estriols in insulin-dependent diabetic pregnancies: normative data and clinical relevance.

    abstract::The purpose of this study was to establish normative reference values for serum unconjugated estriol (E3) concentrations in insulin-dependent diabetic pregnancy. There were 1973 samples analyzed in 63 diabetic pregnancies not complicated by fetal distress and/or neonatal asphyxia. These samples were compared with 867 ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-999718

    authors: Miodovnik M,Mimouni F,Hertzberg VS,Siddiqi TA,Tsang RC

    更新日期:1988-10-01 00:00:00

  • Conflicts between physicians and patients in non-elective cesarean delivery: incidence and the adequacy of informed consent.

    abstract::A study was undertaken in 372 consecutive patients undergoing non-elective cesarean delivery to explore the incidence and nature of conflicts between physician and patient surrounding the decision to undergo non-elective cesarean delivery; to examine the adequacy of informed consent at the time of non-elective cesarea...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994319

    authors: Lescale KB,Inglis SR,Eddleman KA,Peeper EQ,Chervenak FA,McCullough LB

    更新日期:1996-04-01 00:00:00

  • Obstetric Recommendations in American Congress of Obstetricians and Gynecologists Practice Bulletins versus UpToDate: a comparison.

    abstract:OBJECTIVE:To compare the obstetric recommendations in American Congress of Obstetricians and Gynecologists (ACOG) practice bulletins (PB) with similar topics in UpToDate (UTD). STUDY DESIGN:We accessed all obstetric PB and cross-searched UTD (May 1999-May 2013). We analyzed only the PB which had corresponding UTD chap...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,评审

    doi:10.1055/s-0034-1396684

    authors: Myer EN,Too GT,Hammad IA,Babbar S,Martin CE,Hill JB,Blackwell SB,Chauhan SP

    更新日期:2015-04-01 00:00:00

  • Community-Acquired Pneumonia in Children: Myths and Facts.

    abstract::Community-acquired pneumonia (CAP) is the leading cause of death in children < 5 years of age worldwide. It is also one of the most frequent infectious diseases in children, leading to large antibiotic use and hospitalization even in the industrialized countries. However, the optimal management of CAP in children is s...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,评审

    doi:10.1055/s-0039-1691801

    authors: Yun KW,Wallihan R,Juergensen A,Mejias A,Ramilo O

    更新日期:2019-07-01 00:00:00

  • Middle cerebral artery median peak systolic velocity validation: effect of measurement technique.

    abstract::We sought to validate center-specific published medians and estimate the effects of sonologist and Doppler measurement techniques on middle cerebral artery (MCA) peak systolic velocity (PSV) values. We studied 154 gravidas with normal singletons who underwent MCA PSV measurement at 18 to 35 weeks' gestation by one of ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0030-1249365

    authors: Patterson TM,Alexander A,Szychowski JM,Owen J

    更新日期:2010-09-01 00:00:00

  • Fetal liver biopsy for prenatal diagnosis of carbamoyl phosphate synthetase deficiency.

    abstract::Carbamoyl phosphate synthetase deficiency is a type of an inborn error of metabolism with a poor prognosis. Carbamoyl phosphate synthetase is a liver-specific enzyme, and its deficiency can only be diagnosed by enzyme assay using liver biopsy specimens. A pregnant woman at risk for carbamoyl phosphate synthetase defic...

    journal_title:American journal of perinatology

    pub_type: 杂志文章,评审

    doi:10.1055/s-2007-994579

    authors: Murotsuki J,Uehara S,Okamura K,Yajima A,Oura T,Miyabayashi S

    更新日期:1994-03-01 00:00:00

  • Evolution of the Bacillus Calmette-Guerin Scar and Its Association with Birth and Pregnancy Characteristics in a Prospective Cohort of Infants in Iquitos, Peru.

    abstract:BACKGROUND:Bacillus Calmette-Guerin (BCG) scar formation is considered a visual marker of vaccination and cell-mediated immune response. This study characterized the association between pregnancy and birth characteristics with BCG scar formation. STUDY DESIGN:Pregnant women were enrolled prospectively. Infants were fo...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0038-1676614

    authors: Schiaffino F,Lee GO,Paredes-Olortegui M,Cabrera L,Penataro-Yori P,Gilman RH,Kosek MN

    更新日期:2019-10-01 00:00:00

  • First trimester disulfiram exposure: report of two cases.

    abstract::Disulfiram has been used effectively to deter alcohol consumption in patients with a history of alcohol abuse. Its use in reproductive age women has become increasingly common in recent years, intensifying the risk of fetal exposure. Nonspecific but significant abnormalities have been described in the infants of women...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-2007-994688

    authors: Helmbrecht GD,Hoskins IA

    更新日期:1993-01-01 00:00:00

  • Birth Tourism and Neonatal Intensive Care: A Children's Hospital Experience.

    abstract::Objective The aim of this article is to examine characteristics of birth tourism (BT) neonates admitted to a neonatal intensive care unit (NICU). Methods This was a retrospective review over 3 years; BT cases were identified, and relevant perinatal, medical, social, and financial data were collected and compared with ...

    journal_title:American journal of perinatology

    pub_type: 杂志文章

    doi:10.1055/s-0036-1584139

    authors: Mikhael M,Cleary JP,Dhar V,Chen Y,Nguyen DV,Chang AC

    更新日期:2016-12-01 00:00:00