Abstract:
:Infants of diabetic mothers (IDMs) are at known risk for developing a hypertrophic type of cardiomyopathy. The severity of IDM cardiomyopathy can vary from an incidental finding on echocardiography to an infant with severe symptoms of congestive heart failure. The purpose of this article is to review the pathophysiologic mechanisms involved in the development of cardiomyopathy in IDMs and to discuss the diagnostic tests utilized in making the diagnosis (especially echocardiography) and the potential mechanisms that may result in congestive heart failure. This report will conclude with a review of a 2 1/2 year prospective study of diabetic women who had carefully maintained diabetic control during pregnancy. Although the IDMs in this study continued to have mild evidence of generalized hypertrophy when compared with control newborn infants, none developed symptoms of congestive heart failure. These data support the contention that careful diabetic management in pregnancy reduces the severity of hypertrophic cardiomyopathy in IDMs.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Reller MD,Kaplan Sdoi
10.1055/s-2007-999722subject
Has Abstractpub_date
1988-10-01 00:00:00pages
353-8issue
4eissn
0735-1631issn
1098-8785journal_volume
5pub_type
杂志文章,评审abstract::Objective There is limited data regarding the use of oral hypoglycemic agents (OHAs) in pregnant women with type 2 diabetes mellitus (T2DM). Study Design This was a retrospective cohort study of women with T2DM who were treated with OHA or insulin from the first trimester onward. Bivariate and multivariate logistic re...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1597625
更新日期:2017-06-01 00:00:00
abstract::Fetal exposure to infection and inflammation can result in accelerated lung maturation and simultaneously altered lung development. This alteration is characterized by reduced alveolar and vascular formation that is one of the hallmarks of the changes observed in animal models and in infants with bronchopulmonary dysp...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1714347
更新日期:2020-09-01 00:00:00
abstract::This study was performed at University Medical Center, Lubbock, Texas, from July 1989 to June 1990. We obtained serum gentamicin peak and trough levels in 23 pregnant women with pyelonephritis. The patients were given a loading dose of 2 mg/kg gentamicin, followed by 1.5 mg/kg gentamicin adjusted for obesity every 8 h...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994533
更新日期:1994-01-01 00:00:00
abstract::We evaluated the methodological quality of economic evaluation studies in the field of obstetrics and gynecology published in the last decade. A MEDLINE search was performed to find economic evaluation studies in obstetrics and gynecology from the years 1997 through 2009. We included full economic evaluation studies c...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0032-1323591
更新日期:2013-04-01 00:00:00
abstract::Previous work has shown that fetal hydrographic magnetic resonance imaging (MRI) provided additional information complementary to T2-weighted single-shot fast spin echo (ssFSE) images. The objective of this study was to determine if hydrographic MRI provides better conspicuity of fetal eye structures compared with ssF...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0031-1295636
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:Preterm infants are at risk of encountering oral feeding difficulties which impede on the transition to independent oral feeds. The objective of this study was to identify a pivotal period where regressions are most likely to occur during their oral feeding progression. STUDY DESIGN:This is a retrospective s...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1669947
更新日期:2019-04-01 00:00:00
abstract::A retrospective review of placental materials (membranes, chorionic plate, umbilical cord) derived from preterm birth is reported. All those studied had intact membranes on admission and did not have spontaneous rupture. Those with preterm labor unresponsive to tocolysis, including those with brief and more prolonged ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999710
更新日期:1988-07-01 00:00:00
abstract::Molecular amplification of parvovirus B19 DNA in an amniotic fluid sample was used to confirm the etiologic agent of a case with fetal hydrops. The polymerase chain reaction (PCR) method used is easy and fast to perform. We have a 2-year experience on its use in clinical parvovirus B19 diagnosis. The results are avail...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994518
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVE: American College of Cardiology and American Heart Association (ACC/AHA) published new guidelines which lower the cut-off for hypertension. We sought to evaluate the impact of these guidelines to cost and benefit of various low-dose aspirin prophylaxis approaches. STUDY DESIGN: Decision tree analysis was cre...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1697588
更新日期:2019-10-11 00:00:00
abstract::We compared short-term neonatal outcomes between premature infants with spontaneous preterm birth (s-PTB) and those delivered due to preeclampsia (PEC). Data were collected from women with singleton pregnancies admitted with spontaneous preterm labor (PTL) (2002 to 2005) and PEC (2005 to 2007). Patients delivering 24 ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0029-1234036
更新日期:2010-02-01 00:00:00
abstract::Cardiovascular disease (CVD) is the leading cause of death and disability among women, with more than half occurring in individuals with hypertension. New blood pressure criteria for the diagnosis of hypertension from the American College of Cardiology/American Heart Association recognize that there is no specific blo...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1669441
更新日期:2019-03-01 00:00:00
abstract::Introduction First-trimester ultrasound (US) for anatomy assessment may improve anomaly detection, but it may also increase overall US utilization. We sought to assess the utility of first-trimester US for evaluation of fetal anatomy. Materials and Methods A decision analytic model was created to compare first- plus s...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1579652
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To compare the obstetric recommendations in American Congress of Obstetricians and Gynecologists (ACOG) practice bulletins (PB) with similar topics in UpToDate (UTD). STUDY DESIGN:We accessed all obstetric PB and cross-searched UTD (May 1999-May 2013). We analyzed only the PB which had corresponding UTD chap...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1396684
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE: This work aimed to study perinatal, maternal, and neonatal characteristics of birth tourism (BT) mother-baby dyads and the rate of neonatal intensive care unit (NICU) admissions of BT infants. STUDY DESIGN: Retrospective study at a regional perinatal center comparing BT mother-baby dyads to all dyads. BT in...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0040-1719117
更新日期:2020-11-09 00:00:00
abstract::The objective of this paper is to determine if phenobarbital exposure during pregnancy affects developmental outcome at age 2 years. Between 1991 and 1994, 401 pregnant patients at risk for delivery prior to 34 weeks' gestation were invited to participate; 48 mothers declined entry. Before delivery, pharmacy randomize...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2007-993836
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:Securing an arterial line to monitor continuous blood pressure (BP) is difficult in infants. We aimed to reveal the extent of discrepancies between oscillometric and direct BP. STUDY DESIGN:Infants who required continuous BP monitoring were prospectively enrolled. Direct and indirect BP were simultaneously r...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1383851
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:This study aims to identify risk factors for cesarean delivery (CD) surgical site infection (SSI). study design: Retrospective analysis of 2,739 CDs performed at the University of Pittsburgh in 2011. CD SSIs were defined using National Healthcare Safety Network (NHSN) criteria. Chi-square test and t-test were...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1563548
更新日期:2016-01-01 00:00:00
abstract::Persistent fetal bradycardia is rarely encountered during pregnancy. When it is associated with a complete atrio-ventricular (A-V) block, it may prove dangerous to the fetus or newborn. The prenatal diagnosis is vital because it necessitates close follow-up during pregnancy to detect fetal compromise and proper prepar...
journal_title:American journal of perinatology
pub_type: 杂志文章,评审
doi:10.1055/s-2007-994152
更新日期:1997-07-01 00:00:00
abstract::The objective of this article is to evaluate the plasma levels of coagulation and fibrinolysis parameters in the third trimester of gestation and 72 hr postdelivery. Antithrombin III (ATIII), thrombin-antithrombin III complexes (TAT), heparin cofactor II (HCII), protein C (PC), protein S (PS), tissue plasminogen activ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993903
更新日期:1998-02-01 00:00:00
abstract::The aim of this study is to identify clinical, etiologic, and laboratory factors that potentiate adverse outcome of hyperbilirubinemia among term and late preterm neonates in logistic regression analysis. A retrospective cohort of infants with total serum bilirubin (TSB) ≥ 20 mg/dL from 1995 to 2007 was surveyed. Eigh...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0031-1274506
更新日期:2011-05-01 00:00:00
abstract::Anti-Cw is an uncommon cause of clinically significant hemolytic disease of the newborn (HDN). We report an unusually severe case of HDN due to anti-Cw that required phototherapy and exchange transfusion. We also describe a novel PCR-RFLP method for Cw typing of fetal genomic DNA that was used for prenatal diagnosis i...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993872
更新日期:1999-01-01 00:00:00
abstract::Type 1 cystic sacrococcygeal teratomas, usually associated with good outcome following neonatal resection, must be differentiated at the time of prenatal diagnosis from sonographically similar meningomyeloceles, which carry a grave prognosis. We present an unusual case in which color Doppler imaging assisted correct m...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994089
更新日期:1997-01-01 00:00:00
abstract::We present a case of congenital parvovirus B19 infection in a term neonate manifested with isolated massive hydrothorax and mild anemia. Parvovirus B19 DNA was detected in maternal and neonatal blood as well as in pleural fluid despite lack of suggestive serology. ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0028-1085621
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate temporal trends in opioid use disorder (OUD) during antepartum and postpartum hospitalizations. STUDY DESIGN:This repeated cross-sectional analysis analyzed data from the National (Nationwide) Inpatient Sample. Women aged 15 to 54 years admitted antepartum or postpartum were iden...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1694725
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of pretreatment with obestatin (OB), an endogenous hormone also found in mother's milk, in experimental necrotizing enterocolitis (NEC). STUDY DESIGN:Pups were randomized into four groups: control, OB-control, NEC, and OB-NEC. NEC was induced by asphyxia and hypothermia in the NEC a...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1676491
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE: To determine the association between total gestational weight gain and perinatal outcomes. STUDY DESIGN: Data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-To-Be (NuMoM2b) study were used. Total gestational weight gain was categorized as inadequate, adequate, or excessive based on the 20...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1696640
更新日期:2021-01-01 00:00:00
abstract::There is increasing concern about Chlamydia trachomatis infection during pregnancy, because of reports of increased maternal, fetal, and neonatal risks. Amniotic fluid is known to possess antibacterial activity and has recently been shown to inhibit formation of chlamydial inclusions in McCoy cell culture. To further ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999341
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To evaluate to what extent indicators of placenta insufficiency are associated with low concentrations of insulin-like growth factor 1 (IGF-1) and IGF-1-binding protein-1 (IGFBP-1) in neonatal blood, and to what extent the concentrations of these growth factors are associated with concentrations of proteins w...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1677472
更新日期:2019-12-01 00:00:00
abstract::The most common mechanism of fetal tachycardia is orthodromic reciprocating tachycardia utilizing an accessory atrioventricular connection, however, data regarding accessory connection location in patients with fetal tachycardia is limited. To investigate the location of accessory connections in fetal tachycardia, pos...
journal_title:American journal of perinatology
pub_type: 临床试验,杂志文章
doi:10.1055/s-2003-40014
更新日期:2003-04-01 00:00:00
abstract::A 27-year-old primigravida women was referred for ultrasound studies at 32 weeks' gestation because of the suspicion of fetal ventriculomegaly. Sonographic examination of the fetal brain found a marked shift of the midline, with enlarged left hemisphere and ipsilateral occipital horn, and abnormal convolutions. A 3500...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999330
更新日期:1991-01-01 00:00:00