Microarray profiling of antibody responses against simian-human immunodeficiency virus: postchallenge convergence of reactivities independent of host histocompatibility type and vaccine regimen.

abstract：:Most of the viral DNA extracted from simian virus 40 (SV40)-infected African green monkey kidney cells consists of circular molecules about 5.3 kilobases in contour length. However, about 1% of the viral DNA was found to occur as closed circular dimers that appeared to be formed, preferentially, late in infection. The...

journal_title：Journal of virology

authors： Goff SP,Berg P

更新日期：1977-10-01 00:00:00

abstract：:A member of the family Circoviridae, porcine circovirus type 2 (PCV2), is associated with postweaning multisystemic wasting syndrome (PMWS), a recent emerging disease worldwide. PCV2 is also found in clinically asymptomatic animals. This paradoxical finding makes the syndrome etiology challenging. We developed new ass...

journal_title：Journal of virology

authors： Khaiseb S,Sydler T,Zimmermann D,Pospischil A,Sidler X,Brugnera E

更新日期：2011-11-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection remains a major worldwide health problem despite development of highly effective direct-acting antivirals. HCV rapidly evolves upon acute infection and generates multiple viral variants (quasispecies), leading to immune evasion and persistent viral infection. Identification of epitope...

journal_title：Journal of virology

authors： Tong Y,Li Q,Li R,Xu Y,Pan Y,Niu J,Zhong J

更新日期：2020-08-17 00:00:00

abstract：:We have previously shown that styrylquinolines (SQLs) are integrase inhibitors in vitro. They compete with the long terminal repeat substrate for integrase. Here, we describe the cellular mode of action of these molecules. We show that SQLs do not interfere with virus entry. In fact, concentrations of up to 20 times t...

journal_title：Journal of virology

authors： Bonnenfant S,Thomas CM,Vita C,Subra F,Deprez E,Zouhiri F,Desmaële D,D'Angelo J,Mouscadet JF,Leh H

更新日期：2004-06-01 00:00:00

abstract：:Replication and infectivity of hepatitis C virus (HCV) with a defective genome is ambiguous. We molecularly cloned 38 HCV isolates with defective genomes from 18 patient sera. The structural regions were widely deleted, with the 5' untranslated, core, and NS3-NS5B regions preserved. All of the deletions were in frame,...

journal_title：Journal of virology

authors： Sugiyama K,Suzuki K,Nakazawa T,Funami K,Hishiki T,Ogawa K,Saito S,Shimotohno KW,Suzuki T,Shimizu Y,Tobita R,Hijikata M,Takaku H,Shimotohno K

更新日期：2009-07-01 00:00:00

abstract：:The adenovirus E1A 243R oncoprotein is capable of transactivating the expression of the human proliferating cell nuclear antigen (PCNA) promoter. Mutational analysis of the E1A 243R protein suggested that both its p300/CBP- and p107-binding regions are required for optimal induction of the PCNA promoter (C. Kannabiran...

journal_title：Journal of virology

authors： Lee BH,Liu M,Mathews MB

更新日期：1998-02-01 00:00:00

abstract：:Genotype 1 hepatitis E viruses (HEVs) are restricted to primate hosts, whereas genotype 3 HEVs predominantly infect swine, in addition to primates. In order to identify possible determinants of the host range, infectious recombinant viruses and chimeras of a genotype 1 isolate and a genotype 3 isolate were compared fo...

journal_title：Journal of virology

authors： Nguyen HT,Shukla P,Torian U,Faulk K,Emerson SU

更新日期：2014-01-01 00:00:00

abstract：:A polymorphism in the gene encoding CCR2 is associated with a delay in progression to AIDS in human immunodeficiency virus (HIV)-infected individuals. The polymorphism, CCR2-64I, changes valine 64 of CCR2 to isoleucine. However, it is not clear whether the effect on AIDS progression results from the amino acid change ...

journal_title：Journal of virology

authors： Mariani R,Wong S,Mulder LC,Wilkinson DA,Reinhart AL,LaRosa G,Nibbs R,O'Brien TR,Michael NL,Connor RI,Macdonald M,Busch M,Koup RA,Landau NR

更新日期：1999-03-01 00:00:00

abstract：:The alphaherpesvirus proteins UL31 and UL34 and their homologues in other herpesvirus subfamilies cooperate at the nuclear membrane in the export of nascent herpesvirus capsids. We studied the respective betaherpesvirus proteins M53 and M50 in mouse cytomegalovirus (MCMV). Recently, we established a random approach to...

journal_title：Journal of virology

authors： Popa M,Ruzsics Z,Lötzerich M,Dölken L,Buser C,Walther P,Koszinowski UH

更新日期：2010-09-01 00:00:00

abstract：:The antiviral activity of the double-stranded complex poly(rI) . poly(rC) in cell culture was restored or even surpassed if the constituent homopolymers were administered separately. Poly(rI) primed the cells for the antiviral activity of poly(rC) and poly(rC) primed for poly(rI), but neither poly(rI) nor poly(rC) pri...

journal_title：Journal of virology

authors： De Clercq E,De Somer P

更新日期：1972-05-01 00:00:00

abstract：:The time course and extent of mengovirus production were the same in metaphase-arrested and interphase L-cells, yet the expression of cytopathology was delayed several hours in metaphase cells. ...

journal_title：Journal of virology

authors： Lake RS,Winkler DC,Ludwig EH

更新日期：1970-02-01 00:00:00

abstract：:Previous studies have shown that serum interferon (IFN) production in mice is quantitatively influenced by If loci, whose alleles determine high or low production. Although different loci influence IFN production in response to different inducers, such as Newcastle disease virus, Sendai virus, herpes simplex virus typ...

journal_title：Journal of virology

authors： De Maeyer-Guignard J,Dandoy F,Bailey DW,De Maeyer E

更新日期：1986-06-01 00:00:00

abstract：:Although monkey B virus (herpesvirus simiae; BV) is common in all macaque species, fatal human infections appear to be associated with exposure to rhesus macaques (Macaca mulatta), suggesting that BV isolates from rhesus monkeys may be more lethal to nonmacaques than are BV strains indigenous to other macaque species....

journal_title：Journal of virology

authors： Smith AL,Black DH,Eberle R

更新日期：1998-11-01 00:00:00

abstract：:Coxsackievirus B3 (CVB3) is known to infect stem cells in the neonatal central nervous system. Here, we evaluated the effects of CVB3 infection on the major source and repository of stem cells, the bone marrow (BM). Viral genome was detectable in BM within 24 h of infection, and productive infection of BM cells was ev...

journal_title：Journal of virology

authors： Althof N,Whitton JL

更新日期：2013-03-01 00:00:00

abstract：:Expression of the hepatitis B virus core antigen (HBcAg) in mouse NIH 3T3 fibroblasts has been shown previously (A. McLachlan et al., J. Virol. 61:683-692, 1987) to result in the nuclear localization of this polypeptide. Since the carboxyl terminus of HBcAg contains four clusters of arginine residues which resemble nu...

journal_title：Journal of virology

authors： Eckhardt SG,Milich DR,McLachlan A

更新日期：1991-02-01 00:00:00

abstract：:Antiviral effects were characterized for two oligodeoxyribonucleoside methylphosphonates synthesized in an antisense (3'-TCTTAACC-5') or a sense (5'-AGAATTGG-3') orientation, based on the RNA sequence of the first splice acceptor site of the tat-3 gene of human immunodeficiency virus (HIV) (5'...AGAAUUGG...3'). The de...

journal_title：Journal of virology

authors： Zaia JA,Rossi JJ,Murakawa GJ,Spallone PA,Stephens DA,Kaplan BE,Eritja R,Wallace RB,Cantin EM

更新日期：1988-10-01 00:00:00

abstract：:Herpesvirus saimiri (HVS) is divided into three subgroups, A, B, and C, based on sequence divergence at the left end of genomic DNA in which the saimiri transforming protein (STP) resides. Subgroup A and C strains transform primary common marmoset lymphocytes to interleukin-2-independent growth, whereas subgroup B str...

journal_title：Journal of virology

authors： Choi JK,Ishido S,Jung JU

更新日期：2000-09-01 00:00:00

abstract：:Betanodaviruses, the causal agents of viral nervous necrosis in marine fish, have bipartite positive-sense RNAs as genomes. The larger genomic segment, RNA1 (3.1 kb), encodes an RNA-dependent RNA polymerase, and the smaller genomic segment, RNA2 (1.4 kb), codes for the coat protein. Betanodaviruses have marked host sp...

journal_title：Journal of virology

authors： Iwamoto T,Okinaka Y,Mise K,Mori K,Arimoto M,Okuno T,Nakai T

更新日期：2004-02-01 00:00:00

abstract：:The physical map locations of 62 temperature-sensitive mutations of vaccinia virus WR have been determined by marker rescue experiments, using cloned HindIII fragments of wild-type DNA. Since vaccinia virus DNA is not infectious, marker rescue was performed by infecting monolayers of cells at the nonpermissive tempera...

journal_title：Journal of virology

authors： Ensinger MJ,Rovinsky M

更新日期：1983-11-01 00:00:00

abstract：:Sonchus yellow net virus is a plant nucleorhabdovirus whose nucleocapsid (N), phosphoprotein (P), and polymerase (L) proteins form large viroplasms in the nuclei of infected plants (C. R. F. Martins, J. A. Johnson, D. M. Lawrence, T. J. Choi, A. Pisi, S. L. Tobin, D. Lapidus, J. D. O. Wagner, S. Ruzin, K. McDonald, an...

journal_title：Journal of virology

authors： Deng M,Bragg JN,Ruzin S,Schichnes D,King D,Goodin MM,Jackson AO

更新日期：2007-05-01 00:00:00

abstract：:Mason-Pfizer monkey virus 60-70S RNA has a molecular weight of 8 times 10-6 when analyzed on polyacrylamide gels. Dissociation of 60-70S RNA of Mason-Pfizer monkey virus and murine leukemia virus by heat or formamide (40%) resulted in conversion to identical subunit structures of 2.8 times 10-6 daltons; treatment with...

journal_title：Journal of virology

authors： Schochetman G,Schlom J

更新日期：1975-02-01 00:00:00

abstract：:The envelope protein E of flaviviruses mediates both receptor-binding and membrane fusion. At the virion surface, 180 copies of E are tightly packed and organized in a herringbone-like icosahedral structure, whereas in noninfectious subviral particles, 60 copies are arranged in a T=1 icosahedral symmetry. In both case...

journal_title：Journal of virology

authors： Kiermayr S,Stiasny K,Heinz FX

更新日期：2009-09-01 00:00:00

abstract：:Monoclonal antibodies produced against the prototype cell-adapted Wyoming strain of equine infectious anemia virus (EIAV), a lentivirus, were studied for reactivity with the homologous prototype and 16 heterologous isolates. Eighteen hybridomas producing monoclonal antibodies (MAbs) were isolated. Western blot (immuno...

journal_title：Journal of virology

authors： Hussain KA,Issel CJ,Schnorr KL,Rwambo PM,Montelaro RC

更新日期：1987-10-01 00:00:00

abstract：:Rotavirus plus-strand RNAs not only direct protein synthesis but also serve as templates for the synthesis of the segmented double-stranded RNA (dsRNA) genome. In this study, we identified short-interfering RNAs (siRNAs) for viral genes 5, 8, and 9 that suppressed the expression of NSP1, a nonessential protein; NSP2, ...

journal_title：Journal of virology

authors： Silvestri LS,Taraporewala ZF,Patton JT

更新日期：2004-07-01 00:00:00

abstract：:The helicase-like 1a and polymerase-like 2a proteins of brome mosaic virus (BMV) are required for viral RNA replication in vivo, are present in membrane-bound viral RNA polymerase extracts, and share conservation with the many other members of the alphavirus-like superfamily. To better understand BMV RNA replication a...

journal_title：Journal of virology

authors： Restrepo-Hartwig MA,Ahlquist P

更新日期：1996-12-01 00:00:00

abstract：:To determine whether the tripartite leader is required for efficient translation in adenovirus-infected cells at late times of infection, we constructed recombinant adenoviruses containing the influenza virus nucleocapsid protein (NP) gene expressed under the control of the adenovirus major late promoter (MLP). We cho...

journal_title：Journal of virology

authors： Alonso-Caplen FV,Katze MG,Krug RM

更新日期：1988-05-01 00:00:00

abstract：:In a study of the evolution and distribution of avian retroviruses, we found avian sarcoma and leukosis virus (ASLV) gag genes in 26 species of galliform birds from North America, Central America, eastern Europe, Asia, and Africa. Nineteen of the 26 host species from whom ASLVs were sequenced were not previously known...

journal_title：Journal of virology

authors： Dimcheff DE,Drovetski SV,Krishnan M,Mindell DP

更新日期：2000-05-01 00:00:00

abstract：:The membrane-proximal region of the human immunodeficiency virus type 1 (HIV-1) transmembrane protein (TM) is critical for envelope (Env)-mediated membrane fusion and contains the target for broadly reactive neutralizing antibody 2F5. It has been proposed that 2F5 neutralization might involve interaction of its long, ...

journal_title：Journal of virology

authors： Ou W,Lu N,Yu SS,Silver J

更新日期：2006-03-01 00:00:00

abstract：:Nonpermissive 3T3 cells were infected with purified superhelical simian virus 40 (SV40) deoxyribonucleic acid I (DNA I). One hour after infection, approximately 60% of the intracellular SV40 DNA was converted to relaxed forms. One day after infection, all intracellular SV40 DNA was present as slow-sedimenting material...

journal_title：Journal of virology

authors： Collins CJ,Sauer G

更新日期：1972-09-01 00:00:00

abstract：:Productive replication of human immunodeficiency virus type 1 (HIV-1) occurs efficiently only in humans. The posttranscriptional stages of the HIV-1 life cycle proceed poorly in mouse cells, with a resulting defect in viral assembly and release. Previous work has shown that the presence of human chromosome 2 increases...

journal_title：Journal of virology

authors： Elinav H,Wu Y,Coskun A,Hryckiewicz K,Kemler I,Hu Y,Rogers H,Hao B,Ben Mamoun C,Poeschla E,Sutton R

更新日期：2012-11-01 00:00:00