Membranoproliferative glomerulonephritis type II associated with central serous retinopathy.

Abstract:

:Membranoproliferative glomerulonephritis type II is specifically associated with the presence of dense deposits in the basement membrane of Bruch's membrane, which result in lesions similar to basal laminar drusen, exudative drusen, and retinal pigment epithelial detachments. In advanced stages of this dense-deposit retinopathy, choroidal neovascularization may occur. We observed a 36-year-old patient with membranoproliferative glomerulonephritis type II who developed central serous retinopathy in the presence of specific dense-deposit-associated fundus lesions. The diffuse drusenlike dense deposits (at the level of Bruch's membrane) and associated retinal pigment epithelial detachments appear to contribute to the pathogenesis of central serous retinopathy. Thus changes in Bruch's membrane may be involved in the development of central serous retinopathy.

journal_name

Am J Ophthalmol

authors

Ulbig MR,Riordan-Eva P,Holz FG,Rees HC,Hamilton PA

doi

10.1016/s0002-9394(14)71397-2

subject

Has Abstract

pub_date

1993-10-15 00:00:00

pages

410-3

issue

4

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(14)71397-2

journal_volume

116

pub_type

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